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RIN3 (Ras and Rab interactor 3)

Identity

Alias_symbol (synonym)FLJ22439
Other alias-
HGNC (Hugo) RIN3
LocusID (NCBI) 79890
Atlas_Id 50206
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 93042579 and ends at 93155339 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACIN1 (14q11.2) / RIN3 (14q32.12)CDK7 (5q13.2) / RIN3 (14q32.12)GOLGA5 (14q32.12) / RIN3 (14q32.12)
RIN3 (14q32.12) / RIN3 (14q32.12)TNRC6C (17q25.3) / RIN3 (14q32.12)ZNF394 (7q22.1) / RIN3 (14q32.12)
CDK7 5q13.2 / RIN3 14q32.12GOLGA5 14q32.12 / RIN3 14q32.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RIN3   18751
Cards
Entrez_Gene (NCBI)RIN3  79890  Ras and Rab interactor 3
Aliases
GeneCards (Weizmann)RIN3
Ensembl hg19 (Hinxton)ENSG00000100599 [Gene_View]  chr14:93042579-93155339 [Contig_View]  RIN3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100599 [Gene_View]  chr14:93042579-93155339 [Contig_View]  RIN3 [Vega]
ICGC DataPortalENSG00000100599
TCGA cBioPortalRIN3
AceView (NCBI)RIN3
Genatlas (Paris)RIN3
WikiGenes79890
SOURCE (Princeton)RIN3
Genetics Home Reference (NIH)RIN3
Genomic and cartography
GoldenPath hg19 (UCSC)RIN3  -     chr14:93042579-93155339 +  14q32.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RIN3  -     14q32.12   [Description]    (hg38-Dec_2013)
EnsemblRIN3 - 14q32.12 [CytoView hg19]  RIN3 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBIRIN3 [Mapview hg19]  RIN3 [Mapview hg38]
OMIM610223   
Gene and transcription
Genbank (Entrez)AB060338 AB081753 AK021762 AK026092 AK074176
RefSeq transcript (Entrez)NM_001319987 NM_024832
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)RIN3
Cluster EST : UnigeneHs.326822 [ NCBI ]
CGAP (NCI)Hs.326822
Alternative Splicing GalleryENSG00000100599
Gene ExpressionRIN3 [ NCBI-GEO ]   RIN3 [ EBI - ARRAY_EXPRESS ]   RIN3 [ SEEK ]   RIN3 [ MEM ]
Gene Expression Viewer (FireBrowse)RIN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79890
GTEX Portal (Tissue expression)RIN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TB24   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TB24  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TB24
Splice isoforms : SwissVarQ8TB24
PhosPhoSitePlusQ8TB24
Domaine pattern : Prosite (Expaxy)RA (PS50200)    SH2 (PS50001)    VPS9 (PS51205)   
Domains : Interpro (EBI)RA_dom    SH2    VPS9   
Domain families : Pfam (Sanger)VPS9 (PF02204)   
Domain families : Pfam (NCBI)pfam02204   
Domain families : Smart (EMBL)RA (SM00314)  SH2 (SM00252)  VPS9 (SM00167)  
Conserved Domain (NCBI)RIN3
DMDM Disease mutations79890
Blocks (Seattle)RIN3
PDB (SRS)3U23    4WCI   
PDB (PDBSum)3U23    4WCI   
PDB (IMB)3U23    4WCI   
PDB (RSDB)3U23    4WCI   
Structural Biology KnowledgeBase3U23    4WCI   
SCOP (Structural Classification of Proteins)3U23    4WCI   
CATH (Classification of proteins structures)3U23    4WCI   
SuperfamilyQ8TB24
Human Protein AtlasENSG00000100599
Peptide AtlasQ8TB24
HPRD11494
IPIIPI00745485   IPI00329749   IPI01025151   IPI01024794   IPI01024927   
Protein Interaction databases
DIP (DOE-UCLA)Q8TB24
IntAct (EBI)Q8TB24
FunCoupENSG00000100599
BioGRIDRIN3
STRING (EMBL)RIN3
ZODIACRIN3
Ontologies - Pathways
QuickGOQ8TB24
Ontology : AmiGOGTPase activator activity  protein binding  early endosome  endocytosis  signal transduction  cytoplasmic, membrane-bounded vesicle  Rab guanyl-nucleotide exchange factor activity  Rab GTPase binding  cytoplasmic vesicle  positive regulation of GTPase activity  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  protein binding  early endosome  endocytosis  signal transduction  cytoplasmic, membrane-bounded vesicle  Rab guanyl-nucleotide exchange factor activity  Rab GTPase binding  cytoplasmic vesicle  positive regulation of GTPase activity  positive regulation of GTPase activity  
NDEx NetworkRIN3
Atlas of Cancer Signalling NetworkRIN3
Wikipedia pathwaysRIN3
Orthology - Evolution
OrthoDB79890
GeneTree (enSembl)ENSG00000100599
Phylogenetic Trees/Animal Genes : TreeFamRIN3
HOVERGENQ8TB24
HOGENOMQ8TB24
Homologs : HomoloGeneRIN3
Homology/Alignments : Family Browser (UCSC)RIN3
Gene fusions - Rearrangements
Fusion : MitelmanCDK7/RIN3 [5q13.2/14q32.12]  [t(5;14)(q13;q32)]  
Fusion : MitelmanGOLGA5/RIN3 [14q32.12/14q32.12]  [t(14;14)(q32;q32)]  
Fusion: TCGACDK7 5q13.2 RIN3 14q32.12 PRAD
Fusion: TCGAGOLGA5 14q32.12 RIN3 14q32.12 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIN3
dbVarRIN3
ClinVarRIN3
1000_GenomesRIN3 
Exome Variant ServerRIN3
ExAC (Exome Aggregation Consortium)RIN3 (select the gene name)
Genetic variants : HAPMAP79890
Genomic Variants (DGV)RIN3 [DGVbeta]
DECIPHER (Syndromes)14:93042579-93155339  ENSG00000100599
CONAN: Copy Number AnalysisRIN3 
Mutations
ICGC Data PortalRIN3 
TCGA Data PortalRIN3 
Broad Tumor PortalRIN3
OASIS PortalRIN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRIN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RIN3
DgiDB (Drug Gene Interaction Database)RIN3
DoCM (Curated mutations)RIN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RIN3 (select a term)
intoGenRIN3
Cancer3DRIN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610223   
Orphanet
MedgenRIN3
Genetic Testing Registry RIN3
NextProtQ8TB24 [Medical]
TSGene79890
GENETestsRIN3
Huge Navigator RIN3 [HugePedia]
snp3D : Map Gene to Disease79890
BioCentury BCIQRIN3
ClinGenRIN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79890
Chemical/Pharm GKB GenePA38673
Clinical trialRIN3
Miscellaneous
canSAR (ICR)RIN3 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRIN3
EVEXRIN3
GoPubMedRIN3
iHOPRIN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:17:29 CEST 2017

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