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RIN3 (Ras and Rab interactor 3)

Identity

Alias (NCBI)-
HGNC (Hugo) RIN3
HGNC Alias symbFLJ22439
LocusID (NCBI) 79890
Atlas_Id 50206
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 92513781 and ends at 92688994 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACIN1 (14q11.2)::RIN3 (14q32.12)CDK7 (5q13.2)::RIN3 (14q32.12)GOLGA5 (14q32.12)::RIN3 (14q32.12)
RIN3 (14q32.12)::RIN3 (14q32.12)TNRC6C (17q25.3)::RIN3 (14q32.12)ZNF394 (7q22.1)::RIN3 (14q32.12)
CDK7 5q13.2::RIN3 14q32.12GOLGA5 14q32.12::RIN3 14q32.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RIN3   18751
Cards
Entrez_Gene (NCBI)RIN3    Ras and Rab interactor 3
Aliases
GeneCards (Weizmann)RIN3
Ensembl hg19 (Hinxton)ENSG00000100599 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100599 [Gene_View]  ENSG00000100599 [Sequence]  chr14:92513781-92688994 [Contig_View]  RIN3 [Vega]
ICGC DataPortalENSG00000100599
TCGA cBioPortalRIN3
AceView (NCBI)RIN3
Genatlas (Paris)RIN3
SOURCE (Princeton)RIN3
Genetics Home Reference (NIH)RIN3
Genomic and cartography
GoldenPath hg38 (UCSC)RIN3  -     chr14:92513781-92688994 +  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RIN3  -     14q32.12   [Description]    (hg19-Feb_2009)
GoldenPathRIN3 - 14q32.12 [CytoView hg19]  RIN3 - 14q32.12 [CytoView hg38]
ImmunoBaseENSG00000100599
Genome Data Viewer NCBIRIN3 [Mapview hg19]  
OMIM610223   
Gene and transcription
Genbank (Entrez)AB060338 AB081753 AK021762 AK026092 AK074176
RefSeq transcript (Entrez)NM_001319987 NM_024832
Consensus coding sequences : CCDS (NCBI)RIN3
Gene ExpressionRIN3 [ NCBI-GEO ]   RIN3 [ EBI - ARRAY_EXPRESS ]   RIN3 [ SEEK ]   RIN3 [ MEM ]
Gene Expression Viewer (FireBrowse)RIN3 [ Firebrowse - Broad ]
GenevisibleExpression of RIN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79890
GTEX Portal (Tissue expression)RIN3
Human Protein AtlasENSG00000100599-RIN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TB24   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TB24  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TB24
PhosPhoSitePlusQ8TB24
Domaine pattern : Prosite (Expaxy)RA (PS50200)    SH2 (PS50001)    VPS9 (PS51205)   
Domains : Interpro (EBI)RA_dom    RIN3_SH2    SH2    SH2_dom_sf    VPS9    VPS9_dom_sf   
Domain families : Pfam (Sanger)VPS9 (PF02204)   
Domain families : Pfam (NCBI)pfam02204   
Domain families : Smart (EMBL)SH2 (SM00252)  VPS9 (SM00167)  
Conserved Domain (NCBI)RIN3
PDB (RSDB)3U23    4WCI   
PDB Europe3U23    4WCI   
PDB (PDBSum)3U23    4WCI   
PDB (IMB)3U23    4WCI   
Structural Biology KnowledgeBase3U23    4WCI   
SCOP (Structural Classification of Proteins)3U23    4WCI   
CATH (Classification of proteins structures)3U23    4WCI   
SuperfamilyQ8TB24
AlphaFold pdb e-kbQ8TB24   
Human Protein Atlas [tissue]ENSG00000100599-RIN3 [tissue]
HPRD11494
Protein Interaction databases
DIP (DOE-UCLA)Q8TB24
IntAct (EBI)Q8TB24
BioGRIDRIN3
STRING (EMBL)RIN3
ZODIACRIN3
Ontologies - Pathways
QuickGOQ8TB24
Ontology : AmiGOnegative regulation of receptor internalization  guanyl-nucleotide exchange factor activity  protein binding  cytoplasm  early endosome  cytosol  endocytosis  signal transduction  endocytic vesicle  axon  dendrite  small GTPase binding  small GTPase binding  cytoplasmic vesicle  vesicle  neuronal cell body  regulation of catalytic activity  negative regulation of mast cell chemotaxis  regulation of vesicle size  
Ontology : EGO-EBInegative regulation of receptor internalization  guanyl-nucleotide exchange factor activity  protein binding  cytoplasm  early endosome  cytosol  endocytosis  signal transduction  endocytic vesicle  axon  dendrite  small GTPase binding  small GTPase binding  cytoplasmic vesicle  vesicle  neuronal cell body  regulation of catalytic activity  negative regulation of mast cell chemotaxis  regulation of vesicle size  
NDEx NetworkRIN3
Atlas of Cancer Signalling NetworkRIN3
Wikipedia pathwaysRIN3
Orthology - Evolution
OrthoDB79890
GeneTree (enSembl)ENSG00000100599
Phylogenetic Trees/Animal Genes : TreeFamRIN3
Homologs : HomoloGeneRIN3
Homology/Alignments : Family Browser (UCSC)RIN3
Gene fusions - Rearrangements
Fusion : MitelmanCDK7::RIN3 [5q13.2/14q32.12]  
Fusion : MitelmanGOLGA5::RIN3 [14q32.12/14q32.12]  
Fusion : QuiverRIN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIN3
dbVarRIN3
ClinVarRIN3
MonarchRIN3
1000_GenomesRIN3 
Exome Variant ServerRIN3
GNOMAD BrowserENSG00000100599
Varsome BrowserRIN3
ACMGRIN3 variants
VarityQ8TB24
Genomic Variants (DGV)RIN3 [DGVbeta]
DECIPHERRIN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRIN3 
Mutations
ICGC Data PortalRIN3 
TCGA Data PortalRIN3 
Broad Tumor PortalRIN3
OASIS PortalRIN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRIN3
Mutations and Diseases : HGMDRIN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRIN3
DgiDB (Drug Gene Interaction Database)RIN3
DoCM (Curated mutations)RIN3
CIViC (Clinical Interpretations of Variants in Cancer)RIN3
Cancer3DRIN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610223   
Orphanet
DisGeNETRIN3
MedgenRIN3
Genetic Testing Registry RIN3
NextProtQ8TB24 [Medical]
GENETestsRIN3
Target ValidationRIN3
Huge Navigator RIN3 [HugePedia]
ClinGenRIN3
Clinical trials, drugs, therapy
MyCancerGenomeRIN3
Protein Interactions : CTDRIN3
Pharm GKB GenePA38673
PharosQ8TB24
Clinical trialRIN3
Miscellaneous
canSAR (ICR)RIN3
HarmonizomeRIN3
ARCHS4RIN3
DataMed IndexRIN3
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRIN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 18:31:16 CET 2022

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