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RIOK2 (RIO kinase 2)

Identity

Alias_namesRIO kinase 2 (yeast)
Alias_symbol (synonym)FLJ11159
Other aliasRIO2
HGNC (Hugo) RIOK2
LocusID (NCBI) 55781
Atlas_Id 43471
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 97166746 and ends at 97183301 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RIOK2   18999
Cards
Entrez_Gene (NCBI)RIOK2  55781  RIO kinase 2
AliasesRIO2
GeneCards (Weizmann)RIOK2
Ensembl hg19 (Hinxton)ENSG00000058729 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058729 [Gene_View]  chr5:97166746-97183301 [Contig_View]  RIOK2 [Vega]
ICGC DataPortalENSG00000058729
TCGA cBioPortalRIOK2
AceView (NCBI)RIOK2
Genatlas (Paris)RIOK2
WikiGenes55781
SOURCE (Princeton)RIOK2
Genetics Home Reference (NIH)RIOK2
Genomic and cartography
GoldenPath hg38 (UCSC)RIOK2  -     chr5:97166746-97183301 -  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RIOK2  -     5q15   [Description]    (hg19-Feb_2009)
EnsemblRIOK2 - 5q15 [CytoView hg19]  RIOK2 - 5q15 [CytoView hg38]
Mapping of homologs : NCBIRIOK2 [Mapview hg19]  RIOK2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001697 AK002021 AK225348 BC000953 CA415109
RefSeq transcript (Entrez)NM_001159749 NM_018343
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RIOK2
Cluster EST : UnigeneHs.27021 [ NCBI ]
CGAP (NCI)Hs.27021
Alternative Splicing GalleryENSG00000058729
Gene ExpressionRIOK2 [ NCBI-GEO ]   RIOK2 [ EBI - ARRAY_EXPRESS ]   RIOK2 [ SEEK ]   RIOK2 [ MEM ]
Gene Expression Viewer (FireBrowse)RIOK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55781
GTEX Portal (Tissue expression)RIOK2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVS4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVS4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVS4
Splice isoforms : SwissVarQ9BVS4
PhosPhoSitePlusQ9BVS4
Domaine pattern : Prosite (Expaxy)RIO1 (PS01245)   
Domains : Interpro (EBI)Kinase-like_dom    Rio2    RIO2_wHTH_N    RIO_kinase    RIO_kinase_CS    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Rio2_N (PF09202)   
Domain families : Pfam (NCBI)pfam09202   
Domain families : Smart (EMBL)RIO (SM00090)  
Conserved Domain (NCBI)RIOK2
DMDM Disease mutations55781
Blocks (Seattle)RIOK2
PDB (SRS)5DHF   
PDB (PDBSum)5DHF   
PDB (IMB)5DHF   
PDB (RSDB)5DHF   
Structural Biology KnowledgeBase5DHF   
SCOP (Structural Classification of Proteins)5DHF   
CATH (Classification of proteins structures)5DHF   
SuperfamilyQ9BVS4
Human Protein AtlasENSG00000058729
Peptide AtlasQ9BVS4
HPRD10193
IPIIPI00306406   IPI00964496   IPI00965329   IPI00965992   IPI00930723   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVS4
IntAct (EBI)Q9BVS4
FunCoupENSG00000058729
BioGRIDRIOK2
STRING (EMBL)RIOK2
ZODIACRIOK2
Ontologies - Pathways
QuickGOQ9BVS4
Ontology : AmiGOprotein serine/threonine kinase activity  ATP binding  nucleoplasm  cytoplasm  cytosol  rRNA processing  protein phosphorylation  maturation of SSU-rRNA  preribosome, small subunit precursor  ribosomal small subunit biogenesis  metal ion binding  positive regulation of ribosomal small subunit export from nucleus  positive regulation of rRNA processing  
Ontology : EGO-EBIprotein serine/threonine kinase activity  ATP binding  nucleoplasm  cytoplasm  cytosol  rRNA processing  protein phosphorylation  maturation of SSU-rRNA  preribosome, small subunit precursor  ribosomal small subunit biogenesis  metal ion binding  positive regulation of ribosomal small subunit export from nucleus  positive regulation of rRNA processing  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkRIOK2
Atlas of Cancer Signalling NetworkRIOK2
Wikipedia pathwaysRIOK2
Orthology - Evolution
OrthoDB55781
GeneTree (enSembl)ENSG00000058729
Phylogenetic Trees/Animal Genes : TreeFamRIOK2
HOVERGENQ9BVS4
HOGENOMQ9BVS4
Homologs : HomoloGeneRIOK2
Homology/Alignments : Family Browser (UCSC)RIOK2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIOK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIOK2
dbVarRIOK2
ClinVarRIOK2
1000_GenomesRIOK2 
Exome Variant ServerRIOK2
ExAC (Exome Aggregation Consortium)RIOK2 (select the gene name)
Genetic variants : HAPMAP55781
Genomic Variants (DGV)RIOK2 [DGVbeta]
DECIPHERRIOK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRIOK2 
Mutations
ICGC Data PortalRIOK2 
TCGA Data PortalRIOK2 
Broad Tumor PortalRIOK2
OASIS PortalRIOK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIOK2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRIOK2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RIOK2
DgiDB (Drug Gene Interaction Database)RIOK2
DoCM (Curated mutations)RIOK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RIOK2 (select a term)
intoGenRIOK2
Cancer3DRIOK2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRIOK2
Genetic Testing Registry RIOK2
NextProtQ9BVS4 [Medical]
TSGene55781
GENETestsRIOK2
Target ValidationRIOK2
Huge Navigator RIOK2 [HugePedia]
snp3D : Map Gene to Disease55781
BioCentury BCIQRIOK2
ClinGenRIOK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55781
Chemical/Pharm GKB GenePA134885533
Clinical trialRIOK2
Miscellaneous
canSAR (ICR)RIOK2 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRIOK2
EVEXRIOK2
GoPubMedRIOK2
iHOPRIOK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:28:53 CEST 2017

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