Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RIOK3 (RIO kinase 3)

Identity

Alias (NCBI)SUDD
HGNC (Hugo) RIOK3
HGNC Previous nameSUDD
HGNC Previous namesudD (suppressor of bimD6, Aspergillus nidulans) homolog
 RIO kinase 3 (yeast)
LocusID (NCBI) 8780
Atlas_Id 50669
Location 18q11.2  [Link to chromosome band 18q11]
Location_base_pair Starts at 23453287 and ends at 23483140 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OSBPL1A (18q11.2) / RIOK3 (18q11.2)RIOK3 (18q11.2) / RIOK3 (18q11.2)RIOK3 (18q11.2) / TAF4B (18q11.2)
OSBPL1A 18q11.2 / RIOK3 18q11.2RIOK3 18q11.2 / TAF4B 18q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RIOK3   11451
Cards
Entrez_Gene (NCBI)RIOK3    RIO kinase 3
AliasesSUDD
GeneCards (Weizmann)RIOK3
Ensembl hg19 (Hinxton)ENSG00000101782 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101782 [Gene_View]  ENSG00000101782 [Sequence]  chr18:23453287-23483140 [Contig_View]  RIOK3 [Vega]
ICGC DataPortalENSG00000101782
TCGA cBioPortalRIOK3
AceView (NCBI)RIOK3
Genatlas (Paris)RIOK3
SOURCE (Princeton)RIOK3
Genetics Home Reference (NIH)RIOK3
Genomic and cartography
GoldenPath hg38 (UCSC)RIOK3  -     chr18:23453287-23483140 +  18q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RIOK3  -     18q11.2   [Description]    (hg19-Feb_2009)
GoldenPathRIOK3 - 18q11.2 [CytoView hg19]  RIOK3 - 18q11.2 [CytoView hg38]
ImmunoBaseENSG00000101782
Genome Data Viewer NCBIRIOK3 [Mapview hg19]  
OMIM603579   
Gene and transcription
Genbank (Entrez)AF013591 AK024958 AK057292 AK303938 AK304571
RefSeq transcript (Entrez)NM_001348193 NM_003831 NM_145906
Consensus coding sequences : CCDS (NCBI)RIOK3
Gene ExpressionRIOK3 [ NCBI-GEO ]   RIOK3 [ EBI - ARRAY_EXPRESS ]   RIOK3 [ SEEK ]   RIOK3 [ MEM ]
Gene Expression Viewer (FireBrowse)RIOK3 [ Firebrowse - Broad ]
GenevisibleExpression of RIOK3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8780
GTEX Portal (Tissue expression)RIOK3
Human Protein AtlasENSG00000101782-RIOK3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14730   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14730  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14730
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO14730
Domaine pattern : Prosite (Expaxy)RIO1 (PS01245)   
Domains : Interpro (EBI)Kinase-like_dom_sf    RIO_kinase    RIO_kinase_CS    Ser/Thr_kinase_Rio3   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RIO (SM00090)  
Conserved Domain (NCBI)RIOK3
SuperfamilyO14730
AlphaFold pdb e-kbO14730   
Human Protein Atlas [tissue]ENSG00000101782-RIOK3 [tissue]
HPRD04659
Protein Interaction databases
DIP (DOE-UCLA)O14730
IntAct (EBI)O14730
BioGRIDRIOK3
STRING (EMBL)RIOK3
ZODIACRIOK3
Ontologies - Pathways
QuickGOO14730
Ontology : AmiGOprotein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  cytosol  cytosol  protein phosphorylation  chromosome segregation  maturation of SSU-rRNA  maturation of SSU-rRNA  preribosome, small subunit precursor  preribosome, small subunit precursor  negative regulation of protein-containing complex assembly  positive regulation of interferon-beta production  negative regulation of MDA-5 signaling pathway  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of innate immune response  metal ion binding  defense response to virus  cellular response to dsRNA  caspase binding  cellular response to virus  protein serine kinase activity  protein threonine kinase activity  cellular response to dsDNA  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  cytosol  cytosol  protein phosphorylation  chromosome segregation  maturation of SSU-rRNA  maturation of SSU-rRNA  preribosome, small subunit precursor  preribosome, small subunit precursor  negative regulation of protein-containing complex assembly  positive regulation of interferon-beta production  negative regulation of MDA-5 signaling pathway  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of innate immune response  metal ion binding  defense response to virus  cellular response to dsRNA  caspase binding  cellular response to virus  protein serine kinase activity  protein threonine kinase activity  cellular response to dsDNA  
NDEx NetworkRIOK3
Atlas of Cancer Signalling NetworkRIOK3
Wikipedia pathwaysRIOK3
Orthology - Evolution
OrthoDB8780
GeneTree (enSembl)ENSG00000101782
Phylogenetic Trees/Animal Genes : TreeFamRIOK3
Homologs : HomoloGeneRIOK3
Homology/Alignments : Family Browser (UCSC)RIOK3
Gene fusions - Rearrangements
Fusion : MitelmanOSBPL1A/RIOK3 [18q11.2/18q11.2]  
Fusion : MitelmanRIOK3/TAF4B [18q11.2/18q11.2]  
Fusion : QuiverRIOK3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRIOK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RIOK3
dbVarRIOK3
ClinVarRIOK3
MonarchRIOK3
1000_GenomesRIOK3 
Exome Variant ServerRIOK3
GNOMAD BrowserENSG00000101782
Varsome BrowserRIOK3
ACMGRIOK3 variants
VarityO14730
Genomic Variants (DGV)RIOK3 [DGVbeta]
DECIPHERRIOK3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRIOK3 
Mutations
ICGC Data PortalRIOK3 
TCGA Data PortalRIOK3 
Broad Tumor PortalRIOK3
OASIS PortalRIOK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRIOK3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRIOK3
Mutations and Diseases : HGMDRIOK3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRIOK3
DgiDB (Drug Gene Interaction Database)RIOK3
DoCM (Curated mutations)RIOK3
CIViC (Clinical Interpretations of Variants in Cancer)RIOK3
Cancer3DRIOK3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603579   
Orphanet
DisGeNETRIOK3
MedgenRIOK3
Genetic Testing Registry RIOK3
NextProtO14730 [Medical]
GENETestsRIOK3
Target ValidationRIOK3
Huge Navigator RIOK3 [HugePedia]
ClinGenRIOK3
Clinical trials, drugs, therapy
MyCancerGenomeRIOK3
Protein Interactions : CTDRIOK3
Pharm GKB GenePA36248
PharosO14730
Clinical trialRIOK3
Miscellaneous
canSAR (ICR)RIOK3
HarmonizomeRIOK3
DataMed IndexRIOK3
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRIOK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:01 CEST 2021

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