Identity
HGNC
LOCATION
8q21.3
LOCUSID
ALIAS
CARD3,CARDIAK,CCK,GIG30,RICK,RIP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8767
MIM: 603455
HGNC: 10020
Ensembl: ENSG00000104312
Variants:
dbSNP: 8767
ClinVar: 8767
TCGA: ENSG00000104312
COSMIC: RIPK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104312 | ENST00000220751 | O43353 |
| ENSG00000104312 | ENST00000220751 | A0A0S2Z4Z8 |
| ENSG00000104312 | ENST00000517696 | E5RGK6 |
| ENSG00000104312 | ENST00000522965 | E7ERW9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38227684 | 2024 | Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2. | 0 |
| 38227684 | 2024 | Simultaneous substrate and ubiquitin modification recognition by bispecific antibodies enables detection of ubiquitinated RIP1 and RIP2. | 0 |
| 37016317 | 2023 | Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation. | 0 |
| 37488967 | 2023 | NOD1 cooperates with HAX-1 to promote cell migration in a RIPK2- and NF-ĸB-independent manner. | 1 |
| 37914353 | 2023 | Mechanism of Human Cytomegalovirus-Induced Epithelial-Mesenchymal Transition in Glioma Cells via the Upregulation of RIP2 Expression. | 0 |
| 37016317 | 2023 | Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation. | 0 |
| 37488967 | 2023 | NOD1 cooperates with HAX-1 to promote cell migration in a RIPK2- and NF-ĸB-independent manner. | 1 |
| 37914353 | 2023 | Mechanism of Human Cytomegalovirus-Induced Epithelial-Mesenchymal Transition in Glioma Cells via the Upregulation of RIP2 Expression. | 0 |
| 34825931 | 2022 | Activation of RIPK2-mediated NOD1 signaling promotes proliferation and invasion of ovarian cancer cells via NF-κB pathway. | 6 |
| 35033591 | 2022 | Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression via the NOD1/RIPK2/NF-κB pathway. | 32 |
| 35099539 | 2022 | RIP2 Knockdown Attenuates Vascular Smooth Muscle Cells Activation via Negative Regulating Myocardin Expression. | 0 |
| 35115556 | 2022 | Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis. | 12 |
| 35409172 | 2022 | Transcriptional Regulation of RIP2 Gene by NFIB Is Associated with Cellular Immune and Inflammatory Response to APEC Infection. | 7 |
| 35473583 | 2022 | A pancancer analysis of the carcinogenic role of receptor-interacting serine/threonine protein kinase-2 (RIPK2) in human tumours. | 4 |
| 35477477 | 2022 | High expression of RIPK2 is associated with Taxol resistance in serous ovarian cancer. | 2 |
Citation
Dessen P
RIPK2 (receptor interacting serine/threonine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42120/ripk2
