RIPOR2 (RHO family interacting cell polarization regulator 2)

2017-04-01  

Identity

HGNC
RIPOR2
LOCATION
6p22.3
LOCUSID
9750
ALIAS
C6orf32,DFNB104,DIFF40,DIFF48,FAM65B,MYONAP,PL48
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9750
MIM: 611410
HGNC: 13872
Ensembl: ENSG00000111913

Variants:

dbSNP: 9750
ClinVar: 9750
TCGA: ENSG00000111913
COSMIC: RIPOR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111913ENST00000259698Q9Y4F9
ENSG00000111913ENST00000259698A0A024QZY9
ENSG00000111913ENST00000378023Q9Y4F9
ENSG00000111913ENST00000378023A0A024R028
ENSG00000111913ENST00000510784B7Z6U4
ENSG00000111913ENST00000538035F5GX51
ENSG00000111913ENST00000540914F5H029
ENSG00000111913ENST00000613507Q9Y4F9
ENSG00000111913ENST00000613507A0A024QZY9
ENSG00000111913ENST00000643623Q9Y4F9
ENSG00000111913ENST00000643623A0A024R028
ENSG00000111913ENST00000643898A0A2R8YEE0
ENSG00000111913ENST00000644411A0A2R8YF77
ENSG00000111913ENST00000644621Q9Y4F9
ENSG00000111913ENST00000644621A0A024R028
ENSG00000111913ENST00000645100A0A2R8Y7B3
ENSG00000111913ENST00000645703A0A2R8Y4N2
ENSG00000111913ENST00000647136F5H029
ENSG00000111913ENST00000647309A0A2R8Y4B9

References

Pubmed IDYearTitleCitations
249588752014FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.26
171502072007C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia.20
211905622010PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis.18
272690512016Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.14
246879932014Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.12
255888442015Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.12
259530572016Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.9
275565042016FAM65B controls the proliferation of transformed and primary T cells.4
302546312018Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration.2
307206672019Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population.0

Citation

Dessen P

RIPOR2 (RHO family interacting cell polarization regulator 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56806/ripor2