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RLF (rearranged L-myc fusion)

Identity

Other namesZN-15L
ZNF292L
HGNC (Hugo) RLF
LocusID (NCBI) 6018
Atlas_Id 42124
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 40627041 and ends at 40706593 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCL2L1 (20q11.21) / RLF (1p34.2)BMP8B (1p34.2) / RLF (1p34.2)MACF1 (1p34.3) / RLF (1p34.2)
RLF (1p34.2) / BCL2L1 (20q11.21)RLF (1p34.2) / CAP1 (1p34.2)RLF (1p34.2) / COL9A2 (1p34.2)
RLF (1p34.2) / FAM132A (1p36.33)RLF (1p34.2) / GPATCH8 (17q21.31)RLF (1p34.2) / HM13 (20q11.21)
RLF (1p34.2) / IREB2 (15q25.1)RLF (1p34.2) / KPNA6 (1p35.1)RLF (1p34.2) / MACF1 (1p34.3)
RLF (1p34.2) / MFSD2A (1p34.2)RLF (1p34.2) / MYCL (1p34.2)RLF (1p34.2) / NDUFS5 (1p34.3)
RLF (1p34.2) / PPIE (1p34.2)RLF (1p34.2) / PPT1 (1p34.2)RLF (1p34.2) / SMAP2 (1p34.2)
RLF (1p34.2) / TRIT1 (1p34.2)RLF (1p34.2) / UBE2J2 (1p36.33)RLF 1p34.2 / GPATCH8 17q21.31
RLF 1p34.2 / MFSD2A 1p34.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 0 ]
  Lung: Translocations in Small Cell Carcinoma

External links

Nomenclature
HGNC (Hugo)RLF   10025
Cards
Entrez_Gene (NCBI)RLF  6018  rearranged L-myc fusion
AliasesZN-15L; ZNF292L
GeneCards (Weizmann)RLF
Ensembl hg19 (Hinxton)ENSG00000117000 [Gene_View]  chr1:40627041-40706593 [Contig_View]  RLF [Vega]
Ensembl hg38 (Hinxton)ENSG00000117000 [Gene_View]  chr1:40627041-40706593 [Contig_View]  RLF [Vega]
ICGC DataPortalENSG00000117000
TCGA cBioPortalRLF
AceView (NCBI)RLF
Genatlas (Paris)RLF
WikiGenes6018
SOURCE (Princeton)RLF
Genomic and cartography
GoldenPath hg19 (UCSC)RLF  -     chr1:40627041-40706593 +  1p34.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RLF  -     1p34.2   [Description]    (hg38-Dec_2013)
EnsemblRLF - 1p34.2 [CytoView hg19]  RLF - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBIRLF [Mapview hg19]  RLF [Mapview hg38]
OMIM180610   
Gene and transcription
Genbank (Entrez)AB209099 AK307662 BC113666 BM542854 HQ258544
RefSeq transcript (Entrez)NM_012421
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)RLF
Cluster EST : UnigeneHs.205627 [ NCBI ]
CGAP (NCI)Hs.205627
Alternative Splicing GalleryENSG00000117000
Gene ExpressionRLF [ NCBI-GEO ]   RLF [ EBI - ARRAY_EXPRESS ]   RLF [ SEEK ]   RLF [ MEM ]
Gene Expression Viewer (FireBrowse)RLF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6018
GTEX Portal (Tissue expression)RLF
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13129 (Uniprot)
NextProtQ13129  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13129
Splice isoforms : SwissVarQ13129 (Swissvar)
PhosPhoSitePlusQ13129
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
DMDM Disease mutations6018
Blocks (Seattle)RLF
SuperfamilyQ13129
Human Protein AtlasENSG00000117000
Peptide AtlasQ13129
HPRD01614
IPIIPI00018294   IPI01010914   
Protein Interaction databases
DIP (DOE-UCLA)Q13129
IntAct (EBI)Q13129
FunCoupENSG00000117000
BioGRIDRLF
STRING (EMBL)RLF
ZODIACRLF
Ontologies - Pathways
QuickGOQ13129
Ontology : AmiGODNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  DNA integration  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  chromosome organization  chromosome organization  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  DNA integration  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  chromosome organization  chromosome organization  
NDEx Network
Atlas of Cancer Signalling NetworkRLF
Wikipedia pathwaysRLF
Orthology - Evolution
OrthoDB6018
GeneTree (enSembl)ENSG00000117000
Phylogenetic Trees/Animal Genes : TreeFamRLF
Homologs : HomoloGeneRLF
Homology/Alignments : Family Browser (UCSC)RLF
Gene fusions - Rearrangements
Fusion: TCGARLF 1p34.2 GPATCH8 17q21.31 PRAD
Fusion: TCGARLF 1p34.2 MFSD2A 1p34.2 OV
Polymorphisms : SNP, variants
NCBI Variation ViewerRLF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RLF
dbVarRLF
ClinVarRLF
1000_GenomesRLF 
Exome Variant ServerRLF
ExAC (Exome Aggregation Consortium)RLF (select the gene name)
Genetic variants : HAPMAP6018
Genomic Variants (DGV)RLF [DGVbeta]
Mutations
ICGC Data PortalRLF 
TCGA Data PortalRLF 
Broad Tumor PortalRLF
OASIS PortalRLF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRLF 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RLF
DgiDB (Drug Gene Interaction Database)RLF
DoCM (Curated mutations)RLF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RLF (select a term)
intoGenRLF
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:40627041-40706593  ENSG00000117000
CONAN: Copy Number AnalysisRLF 
Mutations and Diseases : HGMDRLF
OMIM180610   
MedgenRLF
Genetic Testing Registry RLF
NextProtQ13129 [Medical]
TSGene6018
GENETestsRLF
Huge Navigator RLF [HugePedia]
snp3D : Map Gene to Disease6018
BioCentury BCIQRLF
ClinGenRLF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6018
Chemical/Pharm GKB GenePA34398
Clinical trialRLF
Miscellaneous
canSAR (ICR)RLF (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRLF
EVEXRLF
GoPubMedRLF
iHOPRLF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:08:33 CEST 2016

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