RLN1 (relaxin 1)

2007-02-01 Affiliation

Identity

HGNC

RLN1

LOCATION

9p24.1

LOCUSID

6013

ALIAS

H1,H1RLX,RLXH1,bA12D24.3.1,bA12D24.3.2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6013
MIM: 179730
HGNC: 10026
Ensembl: ENSG00000107018

Variants:

dbSNP: 6013
ClinVar: 6013
TCGA: ENSG00000107018
COSMIC: RLN1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000107018	ENST00000223862	P04808

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
23704950	2013	Relaxin prevents cardiac fibroblast-myofibroblast transition via notch-1-mediated inhibition of TGF-β/Smad3 signaling.	45
17363522	2007	Relaxin promotes prostate cancer progression.	33
23748429	2013	Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts.	31
16172427	2005	Relaxin increases cardiac output and reduces systemic arterial load in hypertensive rats.	28
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
17804602	2007	Candidate genes controlling pulmonary function in mice: transcript profiling and predicted protein structure.	26
15695505	2005	The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7.	23
24643989	2014	Relaxin augments BMP-2-induced osteoblast differentiation and bone formation.	14
19329780	2009	Toward a stem cell gene therapy for breast cancer.	11
12865351	2003	Adenovirus-mediated expression of human prorelaxin promotes the invasive potential of canine mammary cancer cells.	10

Citation

Dessen P

RLN1 (relaxin 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43920/rln1