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RNASE12 (ribonuclease A family member 12 (inactive))

Identity

Alias_namesribonuclease, RNase A family, 12 (non-active)
Alias_symbol (synonym)RAI1
Other aliasHEL-S-85p
HGNC (Hugo) RNASE12
LocusID (NCBI) 493901
Atlas_Id 72665
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 20590081 and ends at 20590823 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNASE12   24211
Cards
Entrez_Gene (NCBI)RNASE12  493901  ribonuclease A family member 12 (inactive)
AliasesHEL-S-85p; RAI1
GeneCards (Weizmann)RNASE12
Ensembl hg19 (Hinxton)ENSG00000258436 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000258436 [Gene_View]  chr14:20590081-20590823 [Contig_View]  RNASE12 [Vega]
ICGC DataPortalENSG00000258436
TCGA cBioPortalRNASE12
AceView (NCBI)RNASE12
Genatlas (Paris)RNASE12
WikiGenes493901
SOURCE (Princeton)RNASE12
Genetics Home Reference (NIH)RNASE12
Genomic and cartography
GoldenPath hg38 (UCSC)RNASE12  -     chr14:20590081-20590823 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNASE12  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblRNASE12 - 14q11.2 [CytoView hg19]  RNASE12 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIRNASE12 [Mapview hg19]  RNASE12 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AW274139 AY665807 BC130347 BC130349 FJ237362
RefSeq transcript (Entrez)NM_001024822
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNASE12
Cluster EST : UnigeneHs.729466 [ NCBI ]
CGAP (NCI)Hs.729466
Alternative Splicing GalleryENSG00000258436
Gene ExpressionRNASE12 [ NCBI-GEO ]   RNASE12 [ EBI - ARRAY_EXPRESS ]   RNASE12 [ SEEK ]   RNASE12 [ MEM ]
Gene Expression Viewer (FireBrowse)RNASE12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)493901
GTEX Portal (Tissue expression)RNASE12
Human Protein AtlasENSG00000258436-RNASE12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5GAN4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5GAN4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5GAN4
Splice isoforms : SwissVarQ5GAN4
PhosPhoSitePlusQ5GAN4
Domains : Interpro (EBI)RNASE12    RNaseA    RNaseA_domain   
Domain families : Pfam (Sanger)RnaseA (PF00074)   
Domain families : Pfam (NCBI)pfam00074   
Domain families : Smart (EMBL)RNAse_Pc (SM00092)  
Domain structure : Prodom (Prabi Lyon)RNaseA (PD000535)   
Conserved Domain (NCBI)RNASE12
DMDM Disease mutations493901
Blocks (Seattle)RNASE12
SuperfamilyQ5GAN4
Human Protein Atlas [tissue]ENSG00000258436-RNASE12 [tissue]
Peptide AtlasQ5GAN4
HPRD18667
IPIIPI00552100   
Protein Interaction databases
DIP (DOE-UCLA)Q5GAN4
IntAct (EBI)Q5GAN4
FunCoupENSG00000258436
BioGRIDRNASE12
STRING (EMBL)RNASE12
ZODIACRNASE12
Ontologies - Pathways
QuickGOQ5GAN4
Ontology : AmiGOnucleic acid binding  endonuclease activity  ribonuclease activity  extracellular region  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBInucleic acid binding  endonuclease activity  ribonuclease activity  extracellular region  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkRNASE12
Atlas of Cancer Signalling NetworkRNASE12
Wikipedia pathwaysRNASE12
Orthology - Evolution
OrthoDB493901
GeneTree (enSembl)ENSG00000258436
Phylogenetic Trees/Animal Genes : TreeFamRNASE12
HOVERGENQ5GAN4
HOGENOMQ5GAN4
Homologs : HomoloGeneRNASE12
Homology/Alignments : Family Browser (UCSC)RNASE12
Gene fusions - Rearrangements
Tumor Fusion PortalRNASE12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNASE12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNASE12
dbVarRNASE12
ClinVarRNASE12
1000_GenomesRNASE12 
Exome Variant ServerRNASE12
ExAC (Exome Aggregation Consortium)ENSG00000258436
GNOMAD BrowserENSG00000258436
Genetic variants : HAPMAP493901
Genomic Variants (DGV)RNASE12 [DGVbeta]
DECIPHERRNASE12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNASE12 
Mutations
ICGC Data PortalRNASE12 
TCGA Data PortalRNASE12 
Broad Tumor PortalRNASE12
OASIS PortalRNASE12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNASE12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNASE12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNASE12
DgiDB (Drug Gene Interaction Database)RNASE12
DoCM (Curated mutations)RNASE12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNASE12 (select a term)
intoGenRNASE12
Cancer3DRNASE12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRNASE12
MedgenRNASE12
Genetic Testing Registry RNASE12
NextProtQ5GAN4 [Medical]
TSGene493901
GENETestsRNASE12
Target ValidationRNASE12
Huge Navigator RNASE12 [HugePedia]
snp3D : Map Gene to Disease493901
BioCentury BCIQRNASE12
ClinGenRNASE12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD493901
Chemical/Pharm GKB GenePA134948996
Clinical trialRNASE12
Miscellaneous
canSAR (ICR)RNASE12 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNASE12
EVEXRNASE12
GoPubMedRNASE12
iHOPRNASE12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:30:22 CET 2017

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