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RNASEH1 (ribonuclease H1)

Identity

Other aliasH1RNA
PEOB2
RNH1
HGNC (Hugo) RNASEH1
LocusID (NCBI) 246243
Atlas_Id 72673
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 3544892 and ends at 3558371 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNASEH1   18466
LRG (Locus Reference Genomic)LRG_1090
Cards
Entrez_Gene (NCBI)RNASEH1  246243  ribonuclease H1
AliasesH1RNA; PEOB2; RNH1
GeneCards (Weizmann)RNASEH1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:3544892-3558371 [Contig_View]  RNASEH1 [Vega]
TCGA cBioPortalRNASEH1
AceView (NCBI)RNASEH1
Genatlas (Paris)RNASEH1
WikiGenes246243
SOURCE (Princeton)RNASEH1
Genetics Home Reference (NIH)RNASEH1
Genomic and cartography
GoldenPath hg38 (UCSC)RNASEH1  -     chr2:3544892-3558371 -  2p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNASEH1  -     2p25.3   [Description]    (hg19-Feb_2009)
EnsemblRNASEH1 - 2p25.3 [CytoView hg19]  RNASEH1 - 2p25.3 [CytoView hg38]
Mapping of homologs : NCBIRNASEH1 [Mapview hg19]  RNASEH1 [Mapview hg38]
OMIM604123   616479   
Gene and transcription
Genbank (Entrez)AF039652 AF048994 AF048995 AJ224117 AK027610
RefSeq transcript (Entrez)NM_001286834 NM_001286837 NM_002936
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNASEH1
Cluster EST : UnigeneHs.568006 [ NCBI ]
CGAP (NCI)Hs.568006
Gene ExpressionRNASEH1 [ NCBI-GEO ]   RNASEH1 [ EBI - ARRAY_EXPRESS ]   RNASEH1 [ SEEK ]   RNASEH1 [ MEM ]
Gene Expression Viewer (FireBrowse)RNASEH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246243
GTEX Portal (Tissue expression)RNASEH1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60930   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60930  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60930
Splice isoforms : SwissVarO60930
Catalytic activity : Enzyme3.1.26.4 [ Enzyme-Expasy ]   3.1.26.43.1.26.4 [ IntEnz-EBI ]   3.1.26.4 [ BRENDA ]   3.1.26.4 [ KEGG ]   
PhosPhoSitePlusO60930
Domaine pattern : Prosite (Expaxy)RNASE_H (PS50879)   
Domains : Interpro (EBI)Ribosomal_L9/RNase_H1_N    RNase_H1_euk    RNase_H1_N    RNaseH-like_dom    RNaseH_domain   
Domain families : Pfam (Sanger)Cauli_VI (PF01693)    RNase_H (PF00075)   
Domain families : Pfam (NCBI)pfam01693    pfam00075   
Conserved Domain (NCBI)RNASEH1
DMDM Disease mutations246243
Blocks (Seattle)RNASEH1
PDB (SRS)2QK9    2QKB    2QKK    3BSU   
PDB (PDBSum)2QK9    2QKB    2QKK    3BSU   
PDB (IMB)2QK9    2QKB    2QKK    3BSU   
PDB (RSDB)2QK9    2QKB    2QKK    3BSU   
Structural Biology KnowledgeBase2QK9    2QKB    2QKK    3BSU   
SCOP (Structural Classification of Proteins)2QK9    2QKB    2QKK    3BSU   
CATH (Classification of proteins structures)2QK9    2QKB    2QKK    3BSU   
SuperfamilyO60930
Peptide AtlasO60930
HPRD04989
IPIIPI00000077   IPI00894335   IPI00892929   
Protein Interaction databases
DIP (DOE-UCLA)O60930
IntAct (EBI)O60930
BioGRIDRNASEH1
STRING (EMBL)RNASEH1
ZODIACRNASEH1
Ontologies - Pathways
QuickGOO60930
Ontology : AmiGOmagnesium ion binding  nucleic acid binding  RNA binding  RNA-DNA hybrid ribonuclease activity  ribonuclease activity  cytoplasm  RNA catabolic process  DNA replication, removal of RNA primer  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBImagnesium ion binding  nucleic acid binding  RNA binding  RNA-DNA hybrid ribonuclease activity  ribonuclease activity  cytoplasm  RNA catabolic process  DNA replication, removal of RNA primer  RNA phosphodiester bond hydrolysis, endonucleolytic  
Pathways : KEGGDNA replication   
NDEx NetworkRNASEH1
Atlas of Cancer Signalling NetworkRNASEH1
Wikipedia pathwaysRNASEH1
Orthology - Evolution
OrthoDB246243
Phylogenetic Trees/Animal Genes : TreeFamRNASEH1
HOVERGENO60930
HOGENOMO60930
Homologs : HomoloGeneRNASEH1
Homology/Alignments : Family Browser (UCSC)RNASEH1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNASEH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNASEH1
dbVarRNASEH1
ClinVarRNASEH1
1000_GenomesRNASEH1 
Exome Variant ServerRNASEH1
ExAC (Exome Aggregation Consortium)RNASEH1 (select the gene name)
Genetic variants : HAPMAP246243
Genomic Variants (DGV)RNASEH1 [DGVbeta]
DECIPHERRNASEH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNASEH1 
Mutations
ICGC Data PortalRNASEH1 
TCGA Data PortalRNASEH1 
Broad Tumor PortalRNASEH1
OASIS PortalRNASEH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNASEH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNASEH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RNASEH1
DgiDB (Drug Gene Interaction Database)RNASEH1
DoCM (Curated mutations)RNASEH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNASEH1 (select a term)
intoGenRNASEH1
Cancer3DRNASEH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604123    616479   
Orphanet21930   
MedgenRNASEH1
Genetic Testing Registry RNASEH1
NextProtO60930 [Medical]
TSGene246243
GENETestsRNASEH1
Target ValidationRNASEH1
Huge Navigator RNASEH1 [HugePedia]
snp3D : Map Gene to Disease246243
BioCentury BCIQRNASEH1
ClinGenRNASEH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD246243
Chemical/Pharm GKB GenePA38543
Clinical trialRNASEH1
Miscellaneous
canSAR (ICR)RNASEH1 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNASEH1
EVEXRNASEH1
GoPubMedRNASEH1
iHOPRNASEH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:36:22 CEST 2017

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