Identity
HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
AGS2,DLEU8
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79621
MIM: 610326
HGNC: 25671
Ensembl: ENSG00000136104
Variants:
dbSNP: 79621
ClinVar: 79621
TCGA: ENSG00000136104
COSMIC: RNASEH2B
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| DNA replication | KEGG | ko03030 |
| DNA replication | KEGG | hsa03030 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35179959 | 2022 | RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. | 9 |
| 35500843 | 2022 | Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia. | 3 |
| 35179959 | 2022 | RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. | 9 |
| 35500843 | 2022 | Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia. | 3 |
| 33353557 | 2020 | Germline variation of Ribonuclease H2 genes in ovarian cancer patients. | 0 |
| 33353557 | 2020 | Germline variation of Ribonuclease H2 genes in ovarian cancer patients. | 0 |
| 30889214 | 2019 | Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex. | 4 |
| 30889214 | 2019 | Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex. | 4 |
| 29030706 | 2017 | Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. | 11 |
| 29030706 | 2017 | Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis. | 11 |
| 27643693 | 2016 | Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi-Goutières Syndrome and Beyond. | 59 |
| 27643693 | 2016 | Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi-Goutières Syndrome and Beyond. | 59 |
| 25906927 | 2015 | Genetics and molecular biology of brain calcification. | 17 |
| 25906927 | 2015 | Genetics and molecular biology of brain calcification. | 17 |
| 24986920 | 2014 | Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutières syndrome. | 23 |
Citation
Dessen P
RNASEH2B (ribonuclease H2 subunit B)
Atlas Genet Cytogenet Oncol Haematol. 2005-11-01
Online version: http://atlasgeneticsoncology.org/gene/43055/rnaseh2b
