RNASEH2C (ribonuclease H2 subunit C)

2021-06-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
AGS3,AYP1

Other Information

Locus ID:

NCBI: 84153
MIM: 610330
HGNC: 24116
Ensembl: ENSG00000172922

Variants:

dbSNP: 84153
ClinVar: 84153
TCGA: ENSG00000172922
COSMIC: RNASEH2C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172922ENST00000308418Q8TDP1
ENSG00000172922ENST00000308418A0A024R5B3
ENSG00000172922ENST00000527610E9PN81
ENSG00000172922ENST00000531596Q8TDP1
ENSG00000172922ENST00000531596A0A024R5B3
ENSG00000172922ENST00000534482Q8TDP1
ENSG00000172922ENST00000534482A0A024R5B3
ENSG00000172922ENST00000644142Q8TDP1
ENSG00000172922ENST00000644142A0A024R5B3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
DNA replicationKEGGko03030
DNA replicationKEGGhsa03030

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190151522009Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex.54
276436932016Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi-Goutières Syndrome and Beyond.15
249869202014Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutières syndrome.13
82443901993Evidence that the SRY protein is encoded by a single exon on the human Y chromosome.7
311253422019Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer.1

Citation

Dessen P

RNASEH2C (ribonuclease H2 subunit C)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58295/rnaseh2c