Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RNF10 (ring finger protein 10)

Identity

Alias (NCBI)RIE2
HGNC (Hugo) RNF10
HGNC Alias symbKIAA0262
RIE2
LocusID (NCBI) 9921
Atlas_Id 47144
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 120534356 and ends at 120577588 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HOTAIRM1 (7p15.2) / RNF10 (12q24.31)RNF10 (12q24.31) / FBXO21 (12q24.22)RNF10 (12q24.31) / RNF10 (12q24.31)
RNF10 (12q24.31) / SLC28A1 (15q25.3)RNF10 (12q24.31) / SYPL1 (7q22.3)RSU1 (10p13) / RNF10 (12q24.31)
RNF10 12q24.31 / FBXO21 12q24.22RNF10 12q24.31 / SYPL1 7q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RNF10   10055
Cards
Entrez_Gene (NCBI)RNF10    ring finger protein 10
AliasesRIE2
GeneCards (Weizmann)RNF10
Ensembl hg19 (Hinxton)ENSG00000022840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000022840 [Gene_View]  ENSG00000022840 [Sequence]  chr12:120534356-120577588 [Contig_View]  RNF10 [Vega]
ICGC DataPortalENSG00000022840
TCGA cBioPortalRNF10
AceView (NCBI)RNF10
Genatlas (Paris)RNF10
SOURCE (Princeton)RNF10
Genetics Home Reference (NIH)RNF10
Genomic and cartography
GoldenPath hg38 (UCSC)RNF10  -     chr12:120534356-120577588 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF10  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathRNF10 - 12q24.31 [CytoView hg19]  RNF10 - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000022840
genome Data Viewer NCBIRNF10 [Mapview hg19]  
OMIM615998   
Gene and transcription
Genbank (Entrez)AB027196 AK094011 AK097807 AK126274 AK301608
RefSeq transcript (Entrez)NM_001330474 NM_014868
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF10
Alternative Splicing GalleryENSG00000022840
Gene ExpressionRNF10 [ NCBI-GEO ]   RNF10 [ EBI - ARRAY_EXPRESS ]   RNF10 [ SEEK ]   RNF10 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF10 [ Firebrowse - Broad ]
GenevisibleExpression of RNF10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9921
GTEX Portal (Tissue expression)RNF10
Human Protein AtlasENSG00000022840-RNF10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5U6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5U6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5U6
Splice isoforms : SwissVarQ8N5U6
PhosPhoSitePlusQ8N5U6
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Mag2/Rnf10    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF10
Blocks (Seattle)RNF10
SuperfamilyQ8N5U6
Human Protein Atlas [tissue]ENSG00000022840-RNF10 [tissue]
Peptide AtlasQ8N5U6
HPRD11496
IPIIPI00550496   IPI00790489   IPI01012206   IPI01011678   IPI01011215   IPI01010671   IPI01010262   IPI01009295   IPI01010646   IPI01015392   IPI01009726   IPI01014457   IPI01015755   IPI01013574   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5U6
IntAct (EBI)Q8N5U6
BioGRIDRNF10
STRING (EMBL)RNF10
ZODIACRNF10
Ontologies - Pathways
QuickGOQ8N5U6
Ontology : AmiGOtranscription regulatory region sequence-specific DNA binding  transcription regulatory region sequence-specific DNA binding  protein binding  nucleus  cytoplasm  negative regulation of Schwann cell proliferation  positive regulation of myelination  positive regulation of myelination  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
Ontology : EGO-EBItranscription regulatory region sequence-specific DNA binding  transcription regulatory region sequence-specific DNA binding  protein binding  nucleus  cytoplasm  negative regulation of Schwann cell proliferation  positive regulation of myelination  positive regulation of myelination  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
NDEx NetworkRNF10
Atlas of Cancer Signalling NetworkRNF10
Wikipedia pathwaysRNF10
Orthology - Evolution
OrthoDB9921
GeneTree (enSembl)ENSG00000022840
Phylogenetic Trees/Animal Genes : TreeFamRNF10
HOGENOMQ8N5U6
Homologs : HomoloGeneRNF10
Homology/Alignments : Family Browser (UCSC)RNF10
Gene fusions - Rearrangements
Fusion : MitelmanRNF10/FBXO21 [12q24.31/12q24.22]  
Fusion : MitelmanRNF10/SYPL1 [12q24.31/7q22.3]  
Fusion PortalRNF10 12q24.31 FBXO21 12q24.22 LUAD
Fusion PortalRNF10 12q24.31 SYPL1 7q22.3 BRCA
Fusion : QuiverRNF10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF10 [hg38]
dbVarRNF10
ClinVarRNF10
MonarchRNF10
1000_GenomesRNF10 
Exome Variant ServerRNF10
GNOMAD BrowserENSG00000022840
Varsome BrowserRNF10
Genomic Variants (DGV)RNF10 [DGVbeta]
DECIPHERRNF10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF10 
Mutations
ICGC Data PortalRNF10 
TCGA Data PortalRNF10 
Broad Tumor PortalRNF10
OASIS PortalRNF10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF10
Mutations and Diseases : HGMDRNF10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF10
DgiDB (Drug Gene Interaction Database)RNF10
DoCM (Curated mutations)RNF10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF10 (select a term)
intoGenRNF10
Cancer3DRNF10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615998   
Orphanet
DisGeNETRNF10
MedgenRNF10
Genetic Testing Registry RNF10
NextProtQ8N5U6 [Medical]
GENETestsRNF10
Target ValidationRNF10
Huge Navigator RNF10 [HugePedia]
ClinGenRNF10
Clinical trials, drugs, therapy
MyCancerGenomeRNF10
Protein Interactions : CTD
Pharm GKB GenePA34419
PharosQ8N5U6
Clinical trialRNF10
Miscellaneous
canSAR (ICR)RNF10 (select the gene name)
HarmonizomeRNF10
DataMed IndexRNF10
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRNF10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:43:28 CET 2021
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