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RNF10 (ring finger protein 10)

Identity

Alias_symbol (synonym)KIAA0262
RIE2
Other alias
HGNC (Hugo) RNF10
LocusID (NCBI) 9921
Atlas_Id 47144
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 120534330 and ends at 120577594 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HOTAIRM1 (7p15.2) / RNF10 (12q24.31)RNF10 (12q24.31) / FBXO21 (12q24.22)RNF10 (12q24.31) / RNF10 (12q24.31)
RNF10 (12q24.31) / SLC28A1 (15q25.3)RNF10 (12q24.31) / SYPL1 (7q22.3)RSU1 (10p13) / RNF10 (12q24.31)
RNF10 12q24.31 / FBXO21 12q24.22RNF10 12q24.31 / SYPL1 7q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF10   10055
Cards
Entrez_Gene (NCBI)RNF10  9921  ring finger protein 10
AliasesRIE2
GeneCards (Weizmann)RNF10
Ensembl hg19 (Hinxton)ENSG00000022840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000022840 [Gene_View]  chr12:120534330-120577594 [Contig_View]  RNF10 [Vega]
ICGC DataPortalENSG00000022840
TCGA cBioPortalRNF10
AceView (NCBI)RNF10
Genatlas (Paris)RNF10
WikiGenes9921
SOURCE (Princeton)RNF10
Genetics Home Reference (NIH)RNF10
Genomic and cartography
GoldenPath hg38 (UCSC)RNF10  -     chr12:120534330-120577594 +  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF10  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblRNF10 - 12q24.31 [CytoView hg19]  RNF10 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIRNF10 [Mapview hg19]  RNF10 [Mapview hg38]
OMIM615998   
Gene and transcription
Genbank (Entrez)AB027196 AK094011 AK097807 AK126274 AK301608
RefSeq transcript (Entrez)NM_001330474 NM_014868
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF10
Cluster EST : UnigeneHs.442798 [ NCBI ]
CGAP (NCI)Hs.442798
Alternative Splicing GalleryENSG00000022840
Gene ExpressionRNF10 [ NCBI-GEO ]   RNF10 [ EBI - ARRAY_EXPRESS ]   RNF10 [ SEEK ]   RNF10 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9921
GTEX Portal (Tissue expression)RNF10
Human Protein AtlasENSG00000022840-RNF10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5U6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5U6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5U6
Splice isoforms : SwissVarQ8N5U6
PhosPhoSitePlusQ8N5U6
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF10
DMDM Disease mutations9921
Blocks (Seattle)RNF10
SuperfamilyQ8N5U6
Human Protein Atlas [tissue]ENSG00000022840-RNF10 [tissue]
Peptide AtlasQ8N5U6
HPRD11496
IPIIPI00550496   IPI00790489   IPI01012206   IPI01011678   IPI01011215   IPI01010671   IPI01010262   IPI01009295   IPI01010646   IPI01015392   IPI01009726   IPI01014457   IPI01015755   IPI01013574   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5U6
IntAct (EBI)Q8N5U6
FunCoupENSG00000022840
BioGRIDRNF10
STRING (EMBL)RNF10
ZODIACRNF10
Ontologies - Pathways
QuickGOQ8N5U6
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  transcription, DNA-templated  zinc ion binding  negative regulation of Schwann cell proliferation  positive regulation of myelination  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  protein autoubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  transcription, DNA-templated  zinc ion binding  negative regulation of Schwann cell proliferation  positive regulation of myelination  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  protein autoubiquitination  
NDEx NetworkRNF10
Atlas of Cancer Signalling NetworkRNF10
Wikipedia pathwaysRNF10
Orthology - Evolution
OrthoDB9921
GeneTree (enSembl)ENSG00000022840
Phylogenetic Trees/Animal Genes : TreeFamRNF10
HOVERGENQ8N5U6
HOGENOMQ8N5U6
Homologs : HomoloGeneRNF10
Homology/Alignments : Family Browser (UCSC)RNF10
Gene fusions - Rearrangements
Fusion : MitelmanRNF10/FBXO21 [12q24.31/12q24.22]  
Fusion : MitelmanRNF10/SYPL1 [12q24.31/7q22.3]  [t(7;12)(q22;q24)]  
Fusion: TCGA_MDACCRNF10 12q24.31 FBXO21 12q24.22 LUAD
Fusion: TCGA_MDACCRNF10 12q24.31 SYPL1 7q22.3 BRCA
Tumor Fusion PortalRNF10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF10
dbVarRNF10
ClinVarRNF10
1000_GenomesRNF10 
Exome Variant ServerRNF10
ExAC (Exome Aggregation Consortium)ENSG00000022840
GNOMAD BrowserENSG00000022840
Genetic variants : HAPMAP9921
Genomic Variants (DGV)RNF10 [DGVbeta]
DECIPHERRNF10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF10 
Mutations
ICGC Data PortalRNF10 
TCGA Data PortalRNF10 
Broad Tumor PortalRNF10
OASIS PortalRNF10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF10
DgiDB (Drug Gene Interaction Database)RNF10
DoCM (Curated mutations)RNF10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF10 (select a term)
intoGenRNF10
Cancer3DRNF10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615998   
Orphanet
DisGeNETRNF10
MedgenRNF10
Genetic Testing Registry RNF10
NextProtQ8N5U6 [Medical]
TSGene9921
GENETestsRNF10
Target ValidationRNF10
Huge Navigator RNF10 [HugePedia]
snp3D : Map Gene to Disease9921
BioCentury BCIQRNF10
ClinGenRNF10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9921
Chemical/Pharm GKB GenePA34419
Clinical trialRNF10
Miscellaneous
canSAR (ICR)RNF10 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF10
EVEXRNF10
GoPubMedRNF10
iHOPRNF10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:32:34 CET 2017

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