Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RNF111 (ring finger protein 111)

Identity

Alias_symbol (synonym)ARK
Arkadia
FLJ38008
DKFZP761D081
Other aliashRNF111
HGNC (Hugo) RNF111
LocusID (NCBI) 54778
Atlas_Id 42126
Location 15q22.1  [Link to chromosome band 15q22]
Location_base_pair Starts at 58987666 and ends at 59097419 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANTXR2 (4q21.21) / RNF111 (15q22.1)EPC2 (2q23.1) / RNF111 (15q22.1)RNF111 (15q22.1) / RNF111 (15q22.1)
RNF111 (15q22.1) / TCF12 (15q21.3)ZNF280D (15q21.3) / RNF111 (15q22.1)RNF111 15q22.1 / TCF12 15q21.3
ZNF280D 15q21.3 / RNF111 15q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF111   17384
Cards
Entrez_Gene (NCBI)RNF111  54778  ring finger protein 111
AliasesARK; hRNF111
GeneCards (Weizmann)RNF111
Ensembl hg19 (Hinxton)ENSG00000157450 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157450 [Gene_View]  chr15:58987666-59097419 [Contig_View]  RNF111 [Vega]
ICGC DataPortalENSG00000157450
TCGA cBioPortalRNF111
AceView (NCBI)RNF111
Genatlas (Paris)RNF111
WikiGenes54778
SOURCE (Princeton)RNF111
Genetics Home Reference (NIH)RNF111
Genomic and cartography
GoldenPath hg38 (UCSC)RNF111  -     chr15:58987666-59097419 +  15q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF111  -     15q22.1   [Description]    (hg19-Feb_2009)
EnsemblRNF111 - 15q22.1 [CytoView hg19]  RNF111 - 15q22.1 [CytoView hg38]
Mapping of homologs : NCBIRNF111 [Mapview hg19]  RNF111 [Mapview hg38]
OMIM605840   
Gene and transcription
Genbank (Entrez)AI189975 AK095327 AK131304 AK131488 AL157474
RefSeq transcript (Entrez)NM_001270528 NM_001270529 NM_001270530 NM_001330331 NM_017610
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF111
Cluster EST : UnigeneHs.741727 [ NCBI ]
CGAP (NCI)Hs.741727
Alternative Splicing GalleryENSG00000157450
Gene ExpressionRNF111 [ NCBI-GEO ]   RNF111 [ EBI - ARRAY_EXPRESS ]   RNF111 [ SEEK ]   RNF111 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF111 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54778
GTEX Portal (Tissue expression)RNF111
Human Protein AtlasENSG00000157450-RNF111 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNA4
Splice isoforms : SwissVarQ6ZNA4
PhosPhoSitePlusQ6ZNA4
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RNF111_N    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RNF111_N (PF15303)    zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam15303    pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF111
DMDM Disease mutations54778
Blocks (Seattle)RNF111
PDB (SRS)2KIZ   
PDB (PDBSum)2KIZ   
PDB (IMB)2KIZ   
PDB (RSDB)2KIZ   
Structural Biology KnowledgeBase2KIZ   
SCOP (Structural Classification of Proteins)2KIZ   
CATH (Classification of proteins structures)2KIZ   
SuperfamilyQ6ZNA4
Human Protein Atlas [tissue]ENSG00000157450-RNF111 [tissue]
Peptide AtlasQ6ZNA4
HPRD09318
IPIIPI00798384   IPI00829658   IPI00418593   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNA4
IntAct (EBI)Q6ZNA4
FunCoupENSG00000157450
BioGRIDRNF111
STRING (EMBL)RNF111
ZODIACRNF111
Ontologies - Pathways
QuickGOQ6ZNA4
Ontology : AmiGOprotein polyubiquitination  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  pattern specification process  zinc ion binding  protein ubiquitination  PML body  positive regulation of transforming growth factor beta receptor signaling pathway  ubiquitin-dependent SMAD protein catabolic process  positive regulation of protein ubiquitination  SUMO polymer binding  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  protein complex  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  SMAD binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  global genome nucleotide-excision repair  
Ontology : EGO-EBIprotein polyubiquitination  protein binding  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  pattern specification process  zinc ion binding  protein ubiquitination  PML body  positive regulation of transforming growth factor beta receptor signaling pathway  ubiquitin-dependent SMAD protein catabolic process  positive regulation of protein ubiquitination  SUMO polymer binding  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  protein complex  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  SMAD binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  global genome nucleotide-excision repair  
NDEx NetworkRNF111
Atlas of Cancer Signalling NetworkRNF111
Wikipedia pathwaysRNF111
Orthology - Evolution
OrthoDB54778
GeneTree (enSembl)ENSG00000157450
Phylogenetic Trees/Animal Genes : TreeFamRNF111
HOVERGENQ6ZNA4
HOGENOMQ6ZNA4
Homologs : HomoloGeneRNF111
Homology/Alignments : Family Browser (UCSC)RNF111
Gene fusions - Rearrangements
Fusion : MitelmanRNF111/TCF12 [15q22.1/15q21.3]  
Fusion : MitelmanZNF280D/RNF111 [15q21.3/15q22.1]  [t(15;15)(q21;q22)]  
Fusion: TCGA_MDACCRNF111 15q22.1 TCF12 15q21.3 BRCA
Fusion: TCGA_MDACCZNF280D 15q21.3 RNF111 15q22.1 BRCA
Tumor Fusion PortalRNF111
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF111 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF111
dbVarRNF111
ClinVarRNF111
1000_GenomesRNF111 
Exome Variant ServerRNF111
ExAC (Exome Aggregation Consortium)ENSG00000157450
GNOMAD BrowserENSG00000157450
Genetic variants : HAPMAP54778
Genomic Variants (DGV)RNF111 [DGVbeta]
DECIPHERRNF111 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF111 
Mutations
ICGC Data PortalRNF111 
TCGA Data PortalRNF111 
Broad Tumor PortalRNF111
OASIS PortalRNF111 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF111  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF111
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF111
DgiDB (Drug Gene Interaction Database)RNF111
DoCM (Curated mutations)RNF111 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF111 (select a term)
intoGenRNF111
Cancer3DRNF111(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605840   
Orphanet
DisGeNETRNF111
MedgenRNF111
Genetic Testing Registry RNF111
NextProtQ6ZNA4 [Medical]
TSGene54778
GENETestsRNF111
Target ValidationRNF111
Huge Navigator RNF111 [HugePedia]
snp3D : Map Gene to Disease54778
BioCentury BCIQRNF111
ClinGenRNF111
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54778
Chemical/Pharm GKB GenePA134868772
Clinical trialRNF111
Miscellaneous
canSAR (ICR)RNF111 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF111
EVEXRNF111
GoPubMedRNF111
iHOPRNF111
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:32:35 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.