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RNF121 (ring finger protein 121)

Identity

Alias_symbol (synonym)FLJ11099
Other alias-
HGNC (Hugo) RNF121
LocusID (NCBI) 55298
Atlas_Id 46850
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 71928722 and ends at 71997597 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DLEU2 (13q14.2) / RNF121 (11q13.4)PHLDB1 (11q23.3) / RNF121 (11q13.4)PRKAR2B (7q22.3) / RNF121 (11q13.4)
RNF121 (11q13.4) / ANO1 (11q13.3)RNF121 (11q13.4) / ESRRG (1q41)RNF121 (11q13.4) / PCDH9 (13q21.32)
RNF121 (11q13.4) / PPP6R3 (11q13.2)RNF121 (11q13.4) / SF1 (11q13.1)RNF121 (11q13.4) / TRIM37 (17q22)
RNF121 (11q13.4) / VPS37C (11q12.2)RNF121 (11q13.4) / VWA5A (11q24.2)RP11-849H4.2 () / RNF121 (11q13.4)
PHLDB1 11q23.3 / RNF121 11q13.4RNF121 11q13.4 / ANO1 11q13.3RNF121 11q13.4 / ESRRG 1q41
RNF121 11q13.4 / PCDH9 13q21.32RNF121 11q13.4 / PPP6R3 11q13.2RNF121 11q13.4 / SF1 11q13.1
RNF121 11q13.4 / VPS37C 11q12.2RNF121 11q13.4 / VWA5A 11q24.2RP11-849H4.2 RNF121 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF121   21070
Cards
Entrez_Gene (NCBI)RNF121  55298  ring finger protein 121
Aliases
GeneCards (Weizmann)RNF121
Ensembl hg19 (Hinxton)ENSG00000137522 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137522 [Gene_View]  chr11:71928722-71997597 [Contig_View]  RNF121 [Vega]
ICGC DataPortalENSG00000137522
TCGA cBioPortalRNF121
AceView (NCBI)RNF121
Genatlas (Paris)RNF121
WikiGenes55298
SOURCE (Princeton)RNF121
Genetics Home Reference (NIH)RNF121
Genomic and cartography
GoldenPath hg38 (UCSC)RNF121  -     chr11:71928722-71997597 +  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF121  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblRNF121 - 11q13.4 [CytoView hg19]  RNF121 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIRNF121 [Mapview hg19]  RNF121 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI291325 AK001961 AK023139 AK094508 AL833638
RefSeq transcript (Entrez)NM_001300926 NM_018320 NM_194452 NM_194453
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF121
Cluster EST : UnigeneHs.368554 [ NCBI ]
CGAP (NCI)Hs.368554
Alternative Splicing GalleryENSG00000137522
Gene ExpressionRNF121 [ NCBI-GEO ]   RNF121 [ EBI - ARRAY_EXPRESS ]   RNF121 [ SEEK ]   RNF121 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF121 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55298
GTEX Portal (Tissue expression)RNF121
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H920   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H920  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H920
Splice isoforms : SwissVarQ9H920
PhosPhoSitePlusQ9H920
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF121
DMDM Disease mutations55298
Blocks (Seattle)RNF121
SuperfamilyQ9H920
Human Protein AtlasENSG00000137522
Peptide AtlasQ9H920
HPRD11497
IPIIPI00479809   IPI00926203   IPI00926404   IPI01010840   IPI00979400   IPI00975900   IPI01015320   IPI00978712   IPI00976569   
Protein Interaction databases
DIP (DOE-UCLA)Q9H920
IntAct (EBI)Q9H920
FunCoupENSG00000137522
BioGRIDRNF121
STRING (EMBL)RNF121
ZODIACRNF121
Ontologies - Pathways
QuickGOQ9H920
Ontology : AmiGOGolgi membrane  endoplasmic reticulum membrane  zinc ion binding  integral component of membrane  protein ubiquitination  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  ubiquitin protein ligase activity  
Ontology : EGO-EBIGolgi membrane  endoplasmic reticulum membrane  zinc ion binding  integral component of membrane  protein ubiquitination  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  ubiquitin protein ligase activity  
NDEx NetworkRNF121
Atlas of Cancer Signalling NetworkRNF121
Wikipedia pathwaysRNF121
Orthology - Evolution
OrthoDB55298
GeneTree (enSembl)ENSG00000137522
Phylogenetic Trees/Animal Genes : TreeFamRNF121
HOVERGENQ9H920
HOGENOMQ9H920
Homologs : HomoloGeneRNF121
Homology/Alignments : Family Browser (UCSC)RNF121
Gene fusions - Rearrangements
Fusion : MitelmanPHLDB1/RNF121 [11q23.3/11q13.4]  [t(11;11)(q13;q23)]  
Fusion : MitelmanRNF121/ANO1 [11q13.4/11q13.3]  [t(11;11)(q13;q13)]  
Fusion : MitelmanRNF121/ESRRG [11q13.4/1q41]  [t(1;11)(q41;q13)]  
Fusion : MitelmanRNF121/PCDH9 [11q13.4/13q21.32]  [t(11;13)(q13;q21)]  
Fusion : MitelmanRNF121/PPP6R3 [11q13.4/11q13.2]  [t(11;11)(q13;q13)]  
Fusion : MitelmanRNF121/SF1 [11q13.4/11q13.1]  [t(11;11)(q13;q13)]  
Fusion : MitelmanRNF121/TRIM37 [11q13.4/17q22]  [t(11;17)(q13;q22)]  
Fusion : MitelmanRNF121/VPS37C [11q13.4/11q12.2]  [t(11;11)(q12;q13)]  
Fusion : MitelmanRNF121/VWA5A [11q13.4/11q24.2]  [t(11;11)(q13;q24)]  
Fusion: TCGAPHLDB1 11q23.3 RNF121 11q13.4 PRAD
Fusion: TCGARNF121 11q13.4 ANO1 11q13.3 BRCA
Fusion: TCGARNF121 11q13.4 ESRRG 1q41 BRCA
Fusion: TCGARNF121 11q13.4 PCDH9 13q21.32 LUSC
Fusion: TCGARNF121 11q13.4 PPP6R3 11q13.2 BRCA
Fusion: TCGARNF121 11q13.4 SF1 11q13.1 BRCA
Fusion: TCGARNF121 11q13.4 VPS37C 11q12.2 BRCA
Fusion: TCGARNF121 11q13.4 VWA5A 11q24.2 LUAD
Fusion: TCGARP11-849H4.2 RNF121 11q13.4 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF121 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF121
dbVarRNF121
ClinVarRNF121
1000_GenomesRNF121 
Exome Variant ServerRNF121
ExAC (Exome Aggregation Consortium)RNF121 (select the gene name)
Genetic variants : HAPMAP55298
Genomic Variants (DGV)RNF121 [DGVbeta]
DECIPHERRNF121 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF121 
Mutations
ICGC Data PortalRNF121 
TCGA Data PortalRNF121 
Broad Tumor PortalRNF121
OASIS PortalRNF121 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF121  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF121
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF121
DgiDB (Drug Gene Interaction Database)RNF121
DoCM (Curated mutations)RNF121 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF121 (select a term)
intoGenRNF121
Cancer3DRNF121(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRNF121
Genetic Testing Registry RNF121
NextProtQ9H920 [Medical]
TSGene55298
GENETestsRNF121
Target ValidationRNF121
Huge Navigator RNF121 [HugePedia]
snp3D : Map Gene to Disease55298
BioCentury BCIQRNF121
ClinGenRNF121
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55298
Chemical/Pharm GKB GenePA134985388
Clinical trialRNF121
Miscellaneous
canSAR (ICR)RNF121 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF121
EVEXRNF121
GoPubMedRNF121
iHOPRNF121
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:53:27 CEST 2017

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