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RNF125 (ring finger protein 125, E3 ubiquitin protein ligase)

Identity

Alias_namesring finger protein 125
Alias_symbol (synonym)FLJ20456
Other aliasTNORS
TRAC-1
TRAC1
HGNC (Hugo) RNF125
LocusID (NCBI) 54941
Atlas_Id 47479
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 29598445 and ends at 29653154 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RNF138 (18q12.1) / RNF125 (18q12.1)TRAPPC8 (18q12.1) / RNF125 (18q12.1)RNF138 18q12.1 / RNF125 18q12.1
TRAPPC8 18q12.1 / RNF125 18q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF125   21150
Cards
Entrez_Gene (NCBI)RNF125  54941  ring finger protein 125, E3 ubiquitin protein ligase
AliasesTNORS; TRAC-1; TRAC1
GeneCards (Weizmann)RNF125
Ensembl hg19 (Hinxton)ENSG00000101695 [Gene_View]  chr18:29598445-29653154 [Contig_View]  RNF125 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101695 [Gene_View]  chr18:29598445-29653154 [Contig_View]  RNF125 [Vega]
ICGC DataPortalENSG00000101695
TCGA cBioPortalRNF125
AceView (NCBI)RNF125
Genatlas (Paris)RNF125
WikiGenes54941
SOURCE (Princeton)RNF125
Genetics Home Reference (NIH)RNF125
Genomic and cartography
GoldenPath hg19 (UCSC)RNF125  -     chr18:29598445-29653154 +  18q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RNF125  -     18q12.1   [Description]    (hg38-Dec_2013)
EnsemblRNF125 - 18q12.1 [CytoView hg19]  RNF125 - 18q12.1 [CytoView hg38]
Mapping of homologs : NCBIRNF125 [Mapview hg19]  RNF125 [Mapview hg38]
OMIM610432   616260   
Gene and transcription
Genbank (Entrez)AK000463 AK027134 AK225518 BC012021 BI666910
RefSeq transcript (Entrez)NM_017831
RefSeq genomic (Entrez)NC_000018 NC_018929 NG_042056 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)RNF125
Cluster EST : UnigeneHs.633703 [ NCBI ]
CGAP (NCI)Hs.633703
Alternative Splicing GalleryENSG00000101695
Gene ExpressionRNF125 [ NCBI-GEO ]   RNF125 [ EBI - ARRAY_EXPRESS ]   RNF125 [ SEEK ]   RNF125 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF125 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54941
GTEX Portal (Tissue expression)RNF125
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96EQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96EQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96EQ8
Splice isoforms : SwissVarQ96EQ8
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ96EQ8
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Di19_Zn_binding_dom    Znf_C2H2-like    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-Di19 (PF05605)   
Domain families : Pfam (NCBI)pfam05605   
Domain families : Smart (EMBL)RING (SM00184)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)RNF125
DMDM Disease mutations54941
Blocks (Seattle)RNF125
SuperfamilyQ96EQ8
Human Protein AtlasENSG00000101695
Peptide AtlasQ96EQ8
HPRD11500
IPIIPI00410652   
Protein Interaction databases
DIP (DOE-UCLA)Q96EQ8
IntAct (EBI)Q96EQ8
FunCoupENSG00000101695
BioGRIDRNF125
STRING (EMBL)RNF125
ZODIACRNF125
Ontologies - Pathways
QuickGOQ96EQ8
Ontology : AmiGOprotein polyubiquitination  adaptive immune response  intracellular  zinc ion binding  ligase activity  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  adaptive immune response  intracellular  zinc ion binding  ligase activity  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  
Pathways : KEGGRIG-I-like receptor signaling pathway   
NDEx NetworkRNF125
Atlas of Cancer Signalling NetworkRNF125
Wikipedia pathwaysRNF125
Orthology - Evolution
OrthoDB54941
GeneTree (enSembl)ENSG00000101695
Phylogenetic Trees/Animal Genes : TreeFamRNF125
HOVERGENQ96EQ8
HOGENOMQ96EQ8
Homologs : HomoloGeneRNF125
Homology/Alignments : Family Browser (UCSC)RNF125
Gene fusions - Rearrangements
Fusion : MitelmanRNF138/RNF125 [18q12.1/18q12.1]  [t(18;18)(q12;q12)]  
Fusion : MitelmanTRAPPC8/RNF125 [18q12.1/18q12.1]  [t(18;18)(q12;q12)]  
Fusion: TCGARNF138 18q12.1 RNF125 18q12.1 BRCA LUAD THCA
Fusion: TCGATRAPPC8 18q12.1 RNF125 18q12.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF125 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF125
dbVarRNF125
ClinVarRNF125
1000_GenomesRNF125 
Exome Variant ServerRNF125
ExAC (Exome Aggregation Consortium)RNF125 (select the gene name)
Genetic variants : HAPMAP54941
Genomic Variants (DGV)RNF125 [DGVbeta]
DECIPHER (Syndromes)18:29598445-29653154  ENSG00000101695
CONAN: Copy Number AnalysisRNF125 
Mutations
ICGC Data PortalRNF125 
TCGA Data PortalRNF125 
Broad Tumor PortalRNF125
OASIS PortalRNF125 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF125  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF125
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF125
DgiDB (Drug Gene Interaction Database)RNF125
DoCM (Curated mutations)RNF125 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF125 (select a term)
intoGenRNF125
Cancer3DRNF125(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610432    616260   
Orphanet
MedgenRNF125
Genetic Testing Registry RNF125
NextProtQ96EQ8 [Medical]
TSGene54941
GENETestsRNF125
Huge Navigator RNF125 [HugePedia]
snp3D : Map Gene to Disease54941
BioCentury BCIQRNF125
ClinGenRNF125
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54941
Chemical/Pharm GKB GenePA134950383
Clinical trialRNF125
Miscellaneous
canSAR (ICR)RNF125 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF125
EVEXRNF125
GoPubMedRNF125
iHOPRNF125
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:17:37 CEST 2017

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