RNF13 (ring finger protein 13)

2007-04-01  

Identity

HGNC
RNF13
LOCATION
3q25.1
LOCUSID
11342
ALIAS
DEE73,EIEE73,RZF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11342
MIM: 609247
HGNC: 10057
Ensembl: ENSG00000082996

Variants:

dbSNP: 11342
ClinVar: 11342
TCGA: ENSG00000082996
COSMIC: RNF13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000082996ENST00000344229O43567
ENSG00000082996ENST00000361785O43567
ENSG00000082996ENST00000392894O43567
ENSG00000082996ENST00000459632C9JYN7
ENSG00000082996ENST00000466478C9JU37
ENSG00000082996ENST00000466795C9J8T4
ENSG00000082996ENST00000467977C9J7B4
ENSG00000082996ENST00000467996F8WEX6
ENSG00000082996ENST00000468289H7C5Q6
ENSG00000082996ENST00000468648C9JRV0
ENSG00000082996ENST00000470151C9JYY4
ENSG00000082996ENST00000474348F8WDJ5
ENSG00000082996ENST00000482083C9IY58
ENSG00000082996ENST00000490631C9J383
ENSG00000082996ENST00000491086C9JCY0

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
161667382006The role of metallothionein in the pathogenesis of acute lung injury.24
187949102009RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer.14
233785362013RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.10
86101761996Identification and characterization of a RING zinc finger gene (C-RZF) expressed in chicken embryo cells.8
202305302010Nuclear targeting of an endosomal E3 ubiquitin ligase.5
243877862014Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization.5
305953712019Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive.1

Citation

Dessen P

RNF13 (ring finger protein 13)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46675/rnf13