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RNF130 (ring finger protein 130)

Identity

Alias_symbol (synonym)GP
G1RZFP
GOLIATH
HGNC (Hugo) RNF130
LocusID (NCBI) 55819
Atlas_Id 47426
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 179382067 and ends at 179499118 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADAMTS2 (5q35.3) / RNF130 (5q35.3)ARHGAP26 (5q31.3) / RNF130 (5q35.3)C5orf45 (5q35.3) / RNF130 (5q35.3)
HNRNPH1 (5q35.3) / RNF130 (5q35.3)RNF130 (5q35.3) / BRAF (7q34)RNF130 (5q35.3) / RASGEF1C (5q35.3)
RNF130 (5q35.3) / RNF130 (5q35.3)TSPAN13 (7p21.1) / RNF130 (5q35.3)ZDHHC11 (5p15.33) / RNF130 (5q35.3)
RNF130 5q35.3 / BRAF 7q34C5orf45 5q35.3 / RNF130 5q35.3HNRNPH1 5q35.3 / RNF130 5q35.3
RNF130 5q35.3 / RASGEF1C 5q35.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF130   18280
Cards
Entrez_Gene (NCBI)RNF130  55819  ring finger protein 130
AliasesG1RZFP; GOLIATH; GP
GeneCards (Weizmann)RNF130
Ensembl hg19 (Hinxton)ENSG00000113269 [Gene_View]  chr5:179382067-179499118 [Contig_View]  RNF130 [Vega]
Ensembl hg38 (Hinxton)ENSG00000113269 [Gene_View]  chr5:179382067-179499118 [Contig_View]  RNF130 [Vega]
ICGC DataPortalENSG00000113269
TCGA cBioPortalRNF130
AceView (NCBI)RNF130
Genatlas (Paris)RNF130
WikiGenes55819
SOURCE (Princeton)RNF130
Genetics Home Reference (NIH)RNF130
Genomic and cartography
GoldenPath hg19 (UCSC)RNF130  -     chr5:179382067-179499118 -  5q35.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RNF130  -     5q35.3   [Description]    (hg38-Dec_2013)
EnsemblRNF130 - 5q35.3 [CytoView hg19]  RNF130 - 5q35.3 [CytoView hg38]
Mapping of homologs : NCBIRNF130 [Mapview hg19]  RNF130 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA339219 AB209800 AF155650 AK313089 AL515761
RefSeq transcript (Entrez)NM_001280801 NM_018434
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_023133 NW_004929325
Consensus coding sequences : CCDS (NCBI)RNF130
Cluster EST : UnigeneHs.484363 [ NCBI ]
CGAP (NCI)Hs.484363
Alternative Splicing GalleryENSG00000113269
Gene ExpressionRNF130 [ NCBI-GEO ]   RNF130 [ EBI - ARRAY_EXPRESS ]   RNF130 [ SEEK ]   RNF130 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF130 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55819
GTEX Portal (Tissue expression)RNF130
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XS8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XS8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XS8
Splice isoforms : SwissVarQ86XS8
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ86XS8
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)PA_domain    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PA (PF02225)    zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam02225    pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF130
DMDM Disease mutations55819
Blocks (Seattle)RNF130
SuperfamilyQ86XS8
Human Protein AtlasENSG00000113269
Peptide AtlasQ86XS8
HPRD11504
IPIIPI00183643   IPI00978495   IPI00973247   IPI00982148   IPI00979998   
Protein Interaction databases
DIP (DOE-UCLA)Q86XS8
IntAct (EBI)Q86XS8
FunCoupENSG00000113269
BioGRIDRNF130
STRING (EMBL)RNF130
ZODIACRNF130
Ontologies - Pathways
QuickGOQ86XS8
Ontology : AmiGOubiquitin-protein transferase activity  nucleus  cytoplasm  apoptotic process  zinc ion binding  programmed cell death  integral component of membrane  protein ubiquitination  ligase activity  
Ontology : EGO-EBIubiquitin-protein transferase activity  nucleus  cytoplasm  apoptotic process  zinc ion binding  programmed cell death  integral component of membrane  protein ubiquitination  ligase activity  
NDEx NetworkRNF130
Atlas of Cancer Signalling NetworkRNF130
Wikipedia pathwaysRNF130
Orthology - Evolution
OrthoDB55819
GeneTree (enSembl)ENSG00000113269
Phylogenetic Trees/Animal Genes : TreeFamRNF130
HOVERGENQ86XS8
HOGENOMQ86XS8
Homologs : HomoloGeneRNF130
Homology/Alignments : Family Browser (UCSC)RNF130
Gene fusions - Rearrangements
Fusion : MitelmanC5orf45/RNF130 [5q35.3/5q35.3]  [t(5;5)(q35;q35)]  
Fusion : MitelmanHNRNPH1/RNF130 [5q35.3/5q35.3]  [t(5;5)(q35;q35)]  
Fusion : MitelmanRNF130/BRAF [5q35.3/7q34]  [t(5;7)(q35;q34)]  
Fusion : MitelmanRNF130/RASGEF1C [5q35.3/5q35.3]  [t(5;5)(q35;q35)]  
Fusion : MitelmanZDHHC11/RNF130 [5p15.33/5q35.3]  [t(5;5)(p15;q35)]  
Fusion: TCGAC5orf45 5q35.3 RNF130 5q35.3 PRAD
Fusion: TCGAHNRNPH1 5q35.3 RNF130 5q35.3 BRCA
Fusion: TCGARNF130 5q35.3 RASGEF1C 5q35.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF130 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF130
dbVarRNF130
ClinVarRNF130
1000_GenomesRNF130 
Exome Variant ServerRNF130
ExAC (Exome Aggregation Consortium)RNF130 (select the gene name)
Genetic variants : HAPMAP55819
Genomic Variants (DGV)RNF130 [DGVbeta]
DECIPHER (Syndromes)5:179382067-179499118  ENSG00000113269
CONAN: Copy Number AnalysisRNF130 
Mutations
ICGC Data PortalRNF130 
TCGA Data PortalRNF130 
Broad Tumor PortalRNF130
OASIS PortalRNF130 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF130  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF130
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF130
DgiDB (Drug Gene Interaction Database)RNF130
DoCM (Curated mutations)RNF130 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF130 (select a term)
intoGenRNF130
Cancer3DRNF130(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRNF130
Genetic Testing Registry RNF130
NextProtQ86XS8 [Medical]
TSGene55819
GENETestsRNF130
Huge Navigator RNF130 [HugePedia]
snp3D : Map Gene to Disease55819
BioCentury BCIQRNF130
ClinGenRNF130
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55819
Chemical/Pharm GKB GenePA134871556
Clinical trialRNF130
Miscellaneous
canSAR (ICR)RNF130 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF130
EVEXRNF130
GoPubMedRNF130
iHOPRNF130
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:50:03 CET 2016

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