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RNF135 (ring finger protein 135)

Identity

Other namesMMFD
REUL
Riplet
HGNC (Hugo) RNF135
LocusID (NCBI) 84282
Location 17q11.2
Location_base_pair Starts at 29297956 and ends at 29326929 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RNF135   21158
Cards
Entrez_Gene (NCBI)RNF135  84282  ring finger protein 135
GeneCards (Weizmann)RNF135
Ensembl (Hinxton)ENSG00000181481 [Gene_View]  chr17:29297956-29326929 [Contig_View]  RNF135 [Vega]
ICGC DataPortalENSG00000181481
cBioPortalRNF135
AceView (NCBI)RNF135
Genatlas (Paris)RNF135
WikiGenes84282
SOURCE (Princeton)NM_001184992 NM_032322 NM_197939
Genomic and cartography
GoldenPath (UCSC)RNF135  -  17q11.2   chr17:29297956-29326929 +  17q11.2   [Description]    (hg19-Feb_2009)
EnsemblRNF135 - 17q11.2 [CytoView]
Mapping of homologs : NCBIRNF135 [Mapview]
OMIM611358   614192   
Gene and transcription
Genbank (Entrez)AB470605 AI634044 AJ496729 AK122646 AK122709
RefSeq transcript (Entrez)NM_001184992 NM_032322 NM_197939
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_011701 NT_010783 NW_001838430 NW_004929407
Consensus coding sequences : CCDS (NCBI)RNF135
Cluster EST : UnigeneHs.29874 [ NCBI ]
CGAP (NCI)Hs.29874
Alternative Splicing : Fast-db (Paris)GSHG0012376
Alternative Splicing GalleryENSG00000181481
Gene ExpressionRNF135 [ NCBI-GEO ]     RNF135 [ SEEK ]   RNF135 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUD6 (Uniprot)
NextProtQ8IUD6  [Medical]
With graphics : InterProQ8IUD6
Splice isoforms : SwissVarQ8IUD6 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY [organisation]   Butyrophylin [organisation]   ConA-like_lec_gl_sf [organisation]   PRY [organisation]   SPRY_rcpt [organisation]   Znf_RING [organisation]   Znf_RING/FYVE/PHD [organisation]   Znf_RING_CS [organisation]  
Related proteins : CluSTrQ8IUD6
Domain families : Pfam (Sanger)SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam00622   
Domain families : Smart (EMBL)PRY (SM00589)  RING (SM00184)  
DMDM Disease mutations84282
Blocks (Seattle)Q8IUD6
Human Protein AtlasENSG00000181481 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ8IUD6
HPRD11506
IPIIPI00216721   IPI00335645   IPI01011416   IPI00981506   IPI00796911   IPI00798220   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUD6
IntAct (EBI)Q8IUD6
FunCoupENSG00000181481
BioGRIDRNF135
InParanoidQ8IUD6
Interologous Interaction database Q8IUD6
IntegromeDBRNF135
STRING (EMBL)RNF135
Ontologies - Pathways
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  negative regulation of type I interferon production  positive regulation of interferon-beta production  ribonucleoprotein complex binding  innate immune response  regulation of innate immune response  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  negative regulation of type I interferon production  positive regulation of interferon-beta production  ribonucleoprotein complex binding  innate immune response  regulation of innate immune response  
Protein Interaction DatabaseRNF135
Wikipedia pathwaysRNF135
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RNF135
snp3D : Map Gene to Disease84282
SNP (GeneSNP Utah)RNF135
SNP : HGBaseRNF135
Genetic variants : HAPMAPRNF135
Exome VariantRNF135
1000_GenomesRNF135 
ICGC programENSG00000181481 
Somatic Mutations in Cancer : COSMICRNF135 
CONAN: Copy Number AnalysisRNF135 
Mutations and Diseases : HGMDRNF135
Genomic VariantsRNF135  RNF135 [DGVbeta]
dbVarRNF135
ClinVarRNF135
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM611358    614192   
MedgenRNF135
GENETestsRNF135
Disease Genetic AssociationRNF135
Huge Navigator RNF135 [HugePedia]  RNF135 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneRNF135
Homology/Alignments : Family Browser (UCSC)RNF135
Phylogenetic Trees/Animal Genes : TreeFamRNF135
Chemical/Protein Interactions : CTD84282
Chemical/Pharm GKB GenePA134978537
Clinical trialRNF135
Cancer Resource (Charite)ENSG00000181481
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
CoreMineRNF135
iHOPRNF135
OncoSearchRNF135
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:13:24 CEST 2014

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