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RNF138 (ring finger protein 138)

Identity

Alias_namesring finger protein 138
Alias_symbol (synonym)STRIN
NARF
Other aliasHSD-4
hNARF
HGNC (Hugo) RNF138
LocusID (NCBI) 51444
Atlas_Id 46877
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 32092606 and ends at 32131561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RNF138 (18q12.1) / MCM3AP (21q22.3)RNF138 (18q12.1) / RNF125 (18q12.1)RNF138 18q12.1 / RNF125 18q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF138   17765
Cards
Entrez_Gene (NCBI)RNF138  51444  ring finger protein 138
AliasesHSD-4; NARF; STRIN; hNARF
GeneCards (Weizmann)RNF138
Ensembl hg19 (Hinxton)ENSG00000134758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134758 [Gene_View]  chr18:32092606-32131561 [Contig_View]  RNF138 [Vega]
ICGC DataPortalENSG00000134758
TCGA cBioPortalRNF138
AceView (NCBI)RNF138
Genatlas (Paris)RNF138
WikiGenes51444
SOURCE (Princeton)RNF138
Genetics Home Reference (NIH)RNF138
Genomic and cartography
GoldenPath hg38 (UCSC)RNF138  -     chr18:32092606-32131561 +  18q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF138  -     18q12.1   [Description]    (hg19-Feb_2009)
EnsemblRNF138 - 18q12.1 [CytoView hg19]  RNF138 - 18q12.1 [CytoView hg38]
Mapping of homologs : NCBIRNF138 [Mapview hg19]  RNF138 [Mapview hg38]
OMIM616319   
Gene and transcription
Genbank (Entrez)AF162680 AK023579 AK315761 AL133557 BC018107
RefSeq transcript (Entrez)NM_001191324 NM_016271 NM_198128
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF138
Cluster EST : UnigeneHs.302408 [ NCBI ]
CGAP (NCI)Hs.302408
Alternative Splicing GalleryENSG00000134758
Gene ExpressionRNF138 [ NCBI-GEO ]   RNF138 [ EBI - ARRAY_EXPRESS ]   RNF138 [ SEEK ]   RNF138 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF138 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51444
GTEX Portal (Tissue expression)RNF138
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVD3
Splice isoforms : SwissVarQ8WVD3
PhosPhoSitePlusQ8WVD3
Domaine pattern : Prosite (Expaxy)ZF_C2HC_RNF (PS51803)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Di19_Zn_binding_dom    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-Di19 (PF05605)   
Domain families : Pfam (NCBI)pfam05605   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF138
DMDM Disease mutations51444
Blocks (Seattle)RNF138
SuperfamilyQ8WVD3
Human Protein AtlasENSG00000134758
Peptide AtlasQ8WVD3
HPRD11508
IPIIPI00328938   IPI00012239   IPI00983048   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVD3
IntAct (EBI)Q8WVD3
FunCoupENSG00000134758
BioGRIDRNF138
STRING (EMBL)RNF138
ZODIACRNF138
Ontologies - Pathways
QuickGOQ8WVD3
Ontology : AmiGOprotein polyubiquitination  double-strand break repair via homologous recombination  single-stranded DNA binding  protein binding  nucleus  zinc ion binding  DNA double-strand break processing involved in repair via single-strand annealing  Wnt signaling pathway  protein ubiquitination  protein kinase binding  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  site of double-strand break  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  double-strand break repair via homologous recombination  single-stranded DNA binding  protein binding  nucleus  zinc ion binding  DNA double-strand break processing involved in repair via single-strand annealing  Wnt signaling pathway  protein ubiquitination  protein kinase binding  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  site of double-strand break  ubiquitin protein ligase activity  
NDEx NetworkRNF138
Atlas of Cancer Signalling NetworkRNF138
Wikipedia pathwaysRNF138
Orthology - Evolution
OrthoDB51444
GeneTree (enSembl)ENSG00000134758
Phylogenetic Trees/Animal Genes : TreeFamRNF138
HOVERGENQ8WVD3
HOGENOMQ8WVD3
Homologs : HomoloGeneRNF138
Homology/Alignments : Family Browser (UCSC)RNF138
Gene fusions - Rearrangements
Fusion : MitelmanRNF138/RNF125 [18q12.1/18q12.1]  
Fusion: TCGARNF138 18q12.1 RNF125 18q12.1 BRCA LUAD THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF138 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF138
dbVarRNF138
ClinVarRNF138
1000_GenomesRNF138 
Exome Variant ServerRNF138
ExAC (Exome Aggregation Consortium)RNF138 (select the gene name)
Genetic variants : HAPMAP51444
Genomic Variants (DGV)RNF138 [DGVbeta]
DECIPHERRNF138 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF138 
Mutations
ICGC Data PortalRNF138 
TCGA Data PortalRNF138 
Broad Tumor PortalRNF138
OASIS PortalRNF138 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF138  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF138
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF138
DgiDB (Drug Gene Interaction Database)RNF138
DoCM (Curated mutations)RNF138 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF138 (select a term)
intoGenRNF138
Cancer3DRNF138(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616319   
Orphanet
MedgenRNF138
Genetic Testing Registry RNF138
NextProtQ8WVD3 [Medical]
TSGene51444
GENETestsRNF138
Target ValidationRNF138
Huge Navigator RNF138 [HugePedia]
snp3D : Map Gene to Disease51444
BioCentury BCIQRNF138
ClinGenRNF138
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51444
Chemical/Pharm GKB GenePA134952071
Clinical trialRNF138
Miscellaneous
canSAR (ICR)RNF138 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF138
EVEXRNF138
GoPubMedRNF138
iHOPRNF138
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:13:09 CEST 2017

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