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RNF138 (ring finger protein 138)

Identity

Alias (NCBI)HSD-4
NARF
STRIN
hNARF
HGNC (Hugo) RNF138
HGNC Alias symbSTRIN
NARF
HGNC Alias namenemo-like kinase associated ring finger protein
HGNC Previous namering finger protein 138, E3 ubiquitin protein ligase
LocusID (NCBI) 51444
Atlas_Id 46877
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 32092606 and ends at 32131561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RNF138 (18q12.1)::MCM3AP (21q22.3)RNF138 (18q12.1)::RNF125 (18q12.1)RNF138 18q12.1::RNF125 18q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RNF138   17765
Cards
Entrez_Gene (NCBI)RNF138    ring finger protein 138
AliasesHSD-4; NARF; STRIN; hNARF
GeneCards (Weizmann)RNF138
Ensembl hg19 (Hinxton)ENSG00000134758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134758 [Gene_View]  ENSG00000134758 [Sequence]  chr18:32092606-32131561 [Contig_View]  RNF138 [Vega]
ICGC DataPortalENSG00000134758
TCGA cBioPortalRNF138
AceView (NCBI)RNF138
Genatlas (Paris)RNF138
SOURCE (Princeton)RNF138
Genetics Home Reference (NIH)RNF138
Genomic and cartography
GoldenPath hg38 (UCSC)RNF138  -     chr18:32092606-32131561 +  18q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF138  -     18q12.1   [Description]    (hg19-Feb_2009)
GoldenPathRNF138 - 18q12.1 [CytoView hg19]  RNF138 - 18q12.1 [CytoView hg38]
ImmunoBaseENSG00000134758
Genome Data Viewer NCBIRNF138 [Mapview hg19]  
OMIM616319   
Gene and transcription
Genbank (Entrez)AF162680 AK023579 AK315761 AL133557 BC018107
RefSeq transcript (Entrez)NM_001191324 NM_016271 NM_198128
Consensus coding sequences : CCDS (NCBI)RNF138
Gene ExpressionRNF138 [ NCBI-GEO ]   RNF138 [ EBI - ARRAY_EXPRESS ]   RNF138 [ SEEK ]   RNF138 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF138 [ Firebrowse - Broad ]
GenevisibleExpression of RNF138 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51444
GTEX Portal (Tissue expression)RNF138
Human Protein AtlasENSG00000134758-RNF138 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVD3
PhosPhoSitePlusQ8WVD3
Domaine pattern : Prosite (Expaxy)ZF_C2HC_RNF (PS51803)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Di19_Zn-bd    ZF_C2HC_RNF    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-Di19 (PF05605)    zf_C2HC_14 (PF18574)   
Domain families : Pfam (NCBI)pfam05605    pfam18574   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF138
SuperfamilyQ8WVD3
AlphaFold pdb e-kbQ8WVD3   
Human Protein Atlas [tissue]ENSG00000134758-RNF138 [tissue]
HPRD11508
Protein Interaction databases
DIP (DOE-UCLA)Q8WVD3
IntAct (EBI)Q8WVD3
BioGRIDRNF138
STRING (EMBL)RNF138
ZODIACRNF138
Ontologies - Pathways
QuickGOQ8WVD3
Ontology : AmiGOdouble-strand break repair via homologous recombination  double-strand break repair via homologous recombination  single-stranded DNA binding  single-stranded DNA binding  protein binding  nucleus  DNA double-strand break processing involved in repair via single-strand annealing  DNA double-strand break processing involved in repair via single-strand annealing  Wnt signaling pathway  protein ubiquitination  protein ubiquitination  protein kinase binding  site of double-strand break  site of double-strand break  metal ion binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  double-strand break repair via homologous recombination  single-stranded DNA binding  single-stranded DNA binding  protein binding  nucleus  DNA double-strand break processing involved in repair via single-strand annealing  DNA double-strand break processing involved in repair via single-strand annealing  Wnt signaling pathway  protein ubiquitination  protein ubiquitination  protein kinase binding  site of double-strand break  site of double-strand break  metal ion binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  
NDEx NetworkRNF138
Atlas of Cancer Signalling NetworkRNF138
Wikipedia pathwaysRNF138
Orthology - Evolution
OrthoDB51444
GeneTree (enSembl)ENSG00000134758
Phylogenetic Trees/Animal Genes : TreeFamRNF138
Homologs : HomoloGeneRNF138
Homology/Alignments : Family Browser (UCSC)RNF138
Gene fusions - Rearrangements
Fusion : MitelmanRNF138::RNF125 [18q12.1/18q12.1]  
Fusion : QuiverRNF138
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF138 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF138
dbVarRNF138
ClinVarRNF138
MonarchRNF138
1000_GenomesRNF138 
Exome Variant ServerRNF138
GNOMAD BrowserENSG00000134758
Varsome BrowserRNF138
ACMGRNF138 variants
VarityQ8WVD3
Genomic Variants (DGV)RNF138 [DGVbeta]
DECIPHERRNF138 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF138 
Mutations
ICGC Data PortalRNF138 
TCGA Data PortalRNF138 
Broad Tumor PortalRNF138
OASIS PortalRNF138 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF138  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF138
Mutations and Diseases : HGMDRNF138
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRNF138
DgiDB (Drug Gene Interaction Database)RNF138
DoCM (Curated mutations)RNF138
CIViC (Clinical Interpretations of Variants in Cancer)RNF138
Cancer3DRNF138
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616319   
Orphanet
DisGeNETRNF138
MedgenRNF138
Genetic Testing Registry RNF138
NextProtQ8WVD3 [Medical]
GENETestsRNF138
Target ValidationRNF138
Huge Navigator RNF138 [HugePedia]
ClinGenRNF138
Clinical trials, drugs, therapy
MyCancerGenomeRNF138
Protein Interactions : CTDRNF138
Pharm GKB GenePA134952071
PharosQ8WVD3
Clinical trialRNF138
Miscellaneous
canSAR (ICR)RNF138
HarmonizomeRNF138
ARCHS4RNF138
DataMed IndexRNF138
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRNF138
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 18:31:26 CET 2022

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