RNF14 (ring finger protein 14)

2003-08-01  

Identity

HGNC
RNF14
LOCATION
5q31.3
LOCUSID
9604
ALIAS
ARA54,HFB30,HRIHFB2038,TRIAD2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9604
MIM: 605675
HGNC: 10058
Ensembl: ENSG00000013561

Variants:

dbSNP: 9604
ClinVar: 9604
TCGA: ENSG00000013561
COSMIC: RNF14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000013561ENST00000347642Q9UBS8
ENSG00000013561ENST00000356143Q9UBS8
ENSG00000013561ENST00000394514Q9UBS8
ENSG00000013561ENST00000394519Q9UBS8
ENSG00000013561ENST00000394520Q9UBS8
ENSG00000013561ENST00000506004D6RDK2
ENSG00000013561ENST00000506822D6R996
ENSG00000013561ENST00000506938D6RDU6
ENSG00000013561ENST00000507163D6RBU3
ENSG00000013561ENST00000507291D6R988
ENSG00000013561ENST00000511961D6RA38
ENSG00000013561ENST00000512565E7EP22
ENSG00000013561ENST00000513019D6RAS4
ENSG00000013561ENST00000515613D6RBK4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
170823272007Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth.28
116734642002A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth.15
127721882003Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines.15
234494992013Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival.9
171104312007Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54.4
175100802007ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells.3
179196072008Expression of androgen receptor co-regulators in the testes of men with azoospermia.1

Citation

Dessen P

RNF14 (ring finger protein 14)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42130/rnf14