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RNF144B (ring finger protein 144B)

Identity

Alias (NCBI)IBRDC2
PIR2
bA528A10.3
p53RFP
HGNC (Hugo) RNF144B
HGNC Alias symbbA528A10.3
P53RFP
HGNC Previous nameIBRDC2
HGNC Previous nameIBR domain containing 2
LocusID (NCBI) 255488
Atlas_Id 46739
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 18387350 and ends at 18468869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CSGALNACT1 (8p21.3) / RNF144B (6p22.3)DIMT1 (5q12.1) / RNF144B (6p22.3)RNF144B (6p22.3) / LYRM4 (6p25.1)
RNF144B 6p22.3 / LYRM4 6p25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RNF144B   21578
Cards
Entrez_Gene (NCBI)RNF144B    ring finger protein 144B
AliasesIBRDC2; PIR2; bA528A10.3; p53RFP
GeneCards (Weizmann)RNF144B
Ensembl hg19 (Hinxton)ENSG00000137393 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137393 [Gene_View]  ENSG00000137393 [Sequence]  chr6:18387350-18468869 [Contig_View]  RNF144B [Vega]
ICGC DataPortalENSG00000137393
TCGA cBioPortalRNF144B
AceView (NCBI)RNF144B
Genatlas (Paris)RNF144B
SOURCE (Princeton)RNF144B
Genetics Home Reference (NIH)RNF144B
Genomic and cartography
GoldenPath hg38 (UCSC)RNF144B  -     chr6:18387350-18468869 +  6p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF144B  -     6p22.3   [Description]    (hg19-Feb_2009)
GoldenPathRNF144B - 6p22.3 [CytoView hg19]  RNF144B - 6p22.3 [CytoView hg38]
ImmunoBaseENSG00000137393
Genome Data Viewer NCBIRNF144B [Mapview hg19]  
OMIM618869   
Gene and transcription
Genbank (Entrez)AB076367 AJ420555 AK096832 AK302935 AL832329
RefSeq transcript (Entrez)NM_182757
Consensus coding sequences : CCDS (NCBI)RNF144B
Gene ExpressionRNF144B [ NCBI-GEO ]   RNF144B [ EBI - ARRAY_EXPRESS ]   RNF144B [ SEEK ]   RNF144B [ MEM ]
Gene Expression Viewer (FireBrowse)RNF144B [ Firebrowse - Broad ]
GenevisibleExpression of RNF144B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255488
GTEX Portal (Tissue expression)RNF144B
Human Protein AtlasENSG00000137393-RNF144B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z419   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z419  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z419
PhosPhoSitePlusQ7Z419
Domaine pattern : Prosite (Expaxy)TRIAD (PS51873)    ZF_RING_1 (PS00518)   
Domains : Interpro (EBI)E3_UB_ligase_RBR    IBR_dom    TRIAD_supradom    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)IBR (PF01485)   
Domain families : Pfam (NCBI)pfam01485   
Domain families : Smart (EMBL)IBR (SM00647)  RING (SM00184)  
Conserved Domain (NCBI)RNF144B
SuperfamilyQ7Z419
AlphaFold pdb e-kbQ7Z419   
Human Protein Atlas [tissue]ENSG00000137393-RNF144B [tissue]
HPRD17126
Protein Interaction databases
DIP (DOE-UCLA)Q7Z419
IntAct (EBI)Q7Z419
BioGRIDRNF144B
STRING (EMBL)RNF144B
ZODIACRNF144B
Ontologies - Pathways
QuickGOQ7Z419
Ontology : AmiGOubiquitin ligase complex  ubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  ubiquitin-dependent protein catabolic process  apoptotic process  integral component of membrane  ubiquitin conjugating enzyme binding  mitochondrial membrane  mitochondrial membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of apoptotic process  metal ion binding  ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin ligase complex  ubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  ubiquitin-dependent protein catabolic process  apoptotic process  integral component of membrane  ubiquitin conjugating enzyme binding  mitochondrial membrane  mitochondrial membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  negative regulation of apoptotic process  metal ion binding  ubiquitin protein ligase activity  
NDEx NetworkRNF144B
Atlas of Cancer Signalling NetworkRNF144B
Wikipedia pathwaysRNF144B
Orthology - Evolution
OrthoDB255488
GeneTree (enSembl)ENSG00000137393
Phylogenetic Trees/Animal Genes : TreeFamRNF144B
Homologs : HomoloGeneRNF144B
Homology/Alignments : Family Browser (UCSC)RNF144B
Gene fusions - Rearrangements
Fusion : MitelmanRNF144B/LYRM4 [6p22.3/6p25.1]  
Fusion : QuiverRNF144B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF144B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF144B
dbVarRNF144B
ClinVarRNF144B
MonarchRNF144B
1000_GenomesRNF144B 
Exome Variant ServerRNF144B
GNOMAD BrowserENSG00000137393
Varsome BrowserRNF144B
ACMGRNF144B variants
VarityQ7Z419
Genomic Variants (DGV)RNF144B [DGVbeta]
DECIPHERRNF144B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF144B 
Mutations
ICGC Data PortalRNF144B 
TCGA Data PortalRNF144B 
Broad Tumor PortalRNF144B
OASIS PortalRNF144B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF144B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF144B
Mutations and Diseases : HGMDRNF144B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRNF144B
DgiDB (Drug Gene Interaction Database)RNF144B
DoCM (Curated mutations)RNF144B
CIViC (Clinical Interpretations of Variants in Cancer)RNF144B
Cancer3DRNF144B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618869   
Orphanet
DisGeNETRNF144B
MedgenRNF144B
Genetic Testing Registry RNF144B
NextProtQ7Z419 [Medical]
GENETestsRNF144B
Target ValidationRNF144B
Huge Navigator RNF144B [HugePedia]
ClinGenRNF144B
Clinical trials, drugs, therapy
MyCancerGenomeRNF144B
Protein Interactions : CTDRNF144B
Pharm GKB GenePA162401565
PharosQ7Z419
Clinical trialRNF144B
Miscellaneous
canSAR (ICR)RNF144B
HarmonizomeRNF144B
DataMed IndexRNF144B
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRNF144B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:11 CEST 2021

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