Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RNF146 (ring finger protein 146)

Identity

Alias_symbol (synonym)DKFZp434O1427
dactylidin
dJ351K20.1
Other alias-
HGNC (Hugo) RNF146
LocusID (NCBI) 81847
Atlas_Id 47363
Location 6q22.33  [Link to chromosome band 6q22]
Location_base_pair Starts at 127266838 and ends at 127288560 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF146   21336
Cards
Entrez_Gene (NCBI)RNF146  81847  ring finger protein 146
Aliases
GeneCards (Weizmann)RNF146
Ensembl hg19 (Hinxton)ENSG00000118518 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118518 [Gene_View]  ENSG00000118518 [Sequence]  chr6:127266838-127288560 [Contig_View]  RNF146 [Vega]
ICGC DataPortalENSG00000118518
TCGA cBioPortalRNF146
AceView (NCBI)RNF146
Genatlas (Paris)RNF146
WikiGenes81847
SOURCE (Princeton)RNF146
Genetics Home Reference (NIH)RNF146
Genomic and cartography
GoldenPath hg38 (UCSC)RNF146  -     chr6:127266838-127288560 +  6q22.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF146  -     6q22.33   [Description]    (hg19-Feb_2009)
EnsemblRNF146 - 6q22.33 [CytoView hg19]  RNF146 - 6q22.33 [CytoView hg38]
Mapping of homologs : NCBIRNF146 [Mapview hg19]  RNF146 [Mapview hg38]
OMIM612137   
Gene and transcription
Genbank (Entrez)AI929027 AJ315122 AJ420549 AK027436 AK027558
RefSeq transcript (Entrez)NM_001242844 NM_001242845 NM_001242846 NM_001242847 NM_001242848 NM_001242849 NM_001242850 NM_001242851 NM_001242852 NM_030963
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF146
Cluster EST : UnigeneHs.267120 [ NCBI ]
CGAP (NCI)Hs.267120
Alternative Splicing GalleryENSG00000118518
Gene ExpressionRNF146 [ NCBI-GEO ]   RNF146 [ EBI - ARRAY_EXPRESS ]   RNF146 [ SEEK ]   RNF146 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF146 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81847
GTEX Portal (Tissue expression)RNF146
Human Protein AtlasENSG00000118518-RNF146 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NTX7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NTX7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NTX7
Splice isoforms : SwissVarQ9NTX7
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9NTX7
Domaine pattern : Prosite (Expaxy)WWE (PS50918)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RNF146    WWE-dom    WWE-dom_subgr    WWE_dom_sf    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)WWE (PF02825)   
Domain families : Pfam (NCBI)pfam02825   
Domain families : Smart (EMBL)RING (SM00184)  WWE (SM00678)  
Conserved Domain (NCBI)RNF146
DMDM Disease mutations81847
Blocks (Seattle)RNF146
PDB (SRS)2D8T    3V3L   
PDB (PDBSum)2D8T    3V3L   
PDB (IMB)2D8T    3V3L   
PDB (RSDB)2D8T    3V3L   
Structural Biology KnowledgeBase2D8T    3V3L   
SCOP (Structural Classification of Proteins)2D8T    3V3L   
CATH (Classification of proteins structures)2D8T    3V3L   
SuperfamilyQ9NTX7
Human Protein Atlas [tissue]ENSG00000118518-RNF146 [tissue]
Peptide AtlasQ9NTX7
IPIIPI00008911   IPI00550283   
Protein Interaction databases
DIP (DOE-UCLA)Q9NTX7
IntAct (EBI)Q9NTX7
FunCoupENSG00000118518
BioGRIDRNF146
STRING (EMBL)RNF146
ZODIACRNF146
Ontologies - Pathways
QuickGOQ9NTX7
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleoplasm  cytosol  cytosol  plasma membrane  ubiquitin-dependent protein catabolic process  zinc ion binding  Wnt signaling pathway  protein autoubiquitination  ubiquitin protein ligase activity  protein K48-linked ubiquitination  poly-ADP-D-ribose binding  positive regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleoplasm  cytosol  cytosol  plasma membrane  ubiquitin-dependent protein catabolic process  zinc ion binding  Wnt signaling pathway  protein autoubiquitination  ubiquitin protein ligase activity  protein K48-linked ubiquitination  poly-ADP-D-ribose binding  positive regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkRNF146
Atlas of Cancer Signalling NetworkRNF146
Wikipedia pathwaysRNF146
Orthology - Evolution
OrthoDB81847
GeneTree (enSembl)ENSG00000118518
Phylogenetic Trees/Animal Genes : TreeFamRNF146
HOVERGENQ9NTX7
HOGENOMQ9NTX7
Homologs : HomoloGeneRNF146
Homology/Alignments : Family Browser (UCSC)RNF146
Gene fusions - Rearrangements
Fusion : QuiverRNF146
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF146 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF146
dbVarRNF146
ClinVarRNF146
1000_GenomesRNF146 
Exome Variant ServerRNF146
ExAC (Exome Aggregation Consortium)ENSG00000118518
GNOMAD BrowserENSG00000118518
Varsome BrowserRNF146
Genetic variants : HAPMAP81847
Genomic Variants (DGV)RNF146 [DGVbeta]
DECIPHERRNF146 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF146 
Mutations
ICGC Data PortalRNF146 
TCGA Data PortalRNF146 
Broad Tumor PortalRNF146
OASIS PortalRNF146 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF146  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF146
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF146
DgiDB (Drug Gene Interaction Database)RNF146
DoCM (Curated mutations)RNF146 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF146 (select a term)
intoGenRNF146
Cancer3DRNF146(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612137   
Orphanet
DisGeNETRNF146
MedgenRNF146
Genetic Testing Registry RNF146
NextProtQ9NTX7 [Medical]
TSGene81847
GENETestsRNF146
Target ValidationRNF146
Huge Navigator RNF146 [HugePedia]
snp3D : Map Gene to Disease81847
BioCentury BCIQRNF146
ClinGenRNF146
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81847
Chemical/Pharm GKB GenePA134910489
Clinical trialRNF146
Miscellaneous
canSAR (ICR)RNF146 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF146
EVEXRNF146
GoPubMedRNF146
iHOPRNF146
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:35:56 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.