Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81847
MIM: 612137
HGNC: 21336
Ensembl: ENSG00000118518
Variants:
dbSNP: 81847
ClinVar: 81847
TCGA: ENSG00000118518
COSMIC: RNF146
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37029301 | 2023 | SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma. | 5 |
| 37029301 | 2023 | SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma. | 5 |
| 35733260 | 2022 | Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation. | 12 |
| 35733260 | 2022 | Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation. | 12 |
| 34128958 | 2021 | Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs. | 3 |
| 34128958 | 2021 | Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs. | 3 |
| 32958691 | 2020 | Proteome-wide Analysis Reveals Substrates of E3 Ligase RNF146 Targeted for Degradation. | 10 |
| 32958691 | 2020 | Proteome-wide Analysis Reveals Substrates of E3 Ligase RNF146 Targeted for Degradation. | 10 |
| 30974833 | 2019 | Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. | 8 |
| 30974833 | 2019 | Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. | 8 |
| 29932918 | 2018 | The E3 ubiquitin ligase RNF146 promotes colorectal cancer by activating the Wnt/β-catenin pathway via ubiquitination of Axin1. | 13 |
| 29932918 | 2018 | The E3 ubiquitin ligase RNF146 promotes colorectal cancer by activating the Wnt/β-catenin pathway via ubiquitination of Axin1. | 13 |
| 28430183 | 2017 | Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke. | 24 |
| 28430183 | 2017 | Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke. | 24 |
| 25327252 | 2015 | Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. | 124 |
Citation
Dessen P
RNF146 (ring finger protein 146)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47363/rnf146
