RNF152 (ring finger protein 152)

2007-04-01 Affiliation

Identity

HGNC

RNF152

LOCATION

18q21.33

LOCUSID

220441

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 220441
MIM: 616512
HGNC: 26811
Ensembl: ENSG00000176641

Variants:

dbSNP: 220441
ClinVar: 220441
TCGA: ENSG00000176641
COSMIC: RNF152

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000176641	ENST00000312828	Q8N8N0
ENSG00000176641	ENST00000591306	K7EMG3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
mTOR signaling pathway	KEGG	ko04150
mTOR signaling pathway	KEGG	hsa04150
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Protein ubiquitination	REACTOME	R-HSA-8852135
E3 ubiquitin ligases ubiquitinate target proteins	REACTOME	R-HSA-8866654

References

Pubmed ID	Year	Title	Citations
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	75
25936802	2015	The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.	44
21203937	2010	RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activities.	14

Citation

Dessen P

RNF152 (ring finger protein 152)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47113/rnf152