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RNF180 (ring finger protein 180)

Identity

Other aliasRINES
HGNC (Hugo) RNF180
LocusID (NCBI) 285671
Atlas_Id 52691
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 64165843 and ends at 64372869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CASC2 () / RNF180 (5q12.3)CWC27 (5q12.3) / RNF180 (5q12.3)RNF180 (5q12.3) / AKAP13 (15q25.3)
RNF180 (5q12.3) / CASC2 ()

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF180   27752
Cards
Entrez_Gene (NCBI)RNF180  285671  ring finger protein 180
AliasesRINES
GeneCards (Weizmann)RNF180
Ensembl hg19 (Hinxton)ENSG00000164197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164197 [Gene_View]  chr5:64165843-64372869 [Contig_View]  RNF180 [Vega]
ICGC DataPortalENSG00000164197
TCGA cBioPortalRNF180
AceView (NCBI)RNF180
Genatlas (Paris)RNF180
WikiGenes285671
SOURCE (Princeton)RNF180
Genetics Home Reference (NIH)RNF180
Genomic and cartography
GoldenPath hg38 (UCSC)RNF180  -     chr5:64165843-64372869 +  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF180  -     5q12.3   [Description]    (hg19-Feb_2009)
EnsemblRNF180 - 5q12.3 [CytoView hg19]  RNF180 - 5q12.3 [CytoView hg38]
Mapping of homologs : NCBIRNF180 [Mapview hg19]  RNF180 [Mapview hg38]
OMIM616015   
Gene and transcription
Genbank (Entrez)AK090756 AL832580 AM393544 BC101277 BC101278
RefSeq transcript (Entrez)NM_001113561 NM_001323291 NM_001323292 NM_178532
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF180
Cluster EST : UnigeneHs.657843 [ NCBI ]
CGAP (NCI)Hs.657843
Alternative Splicing GalleryENSG00000164197
Gene ExpressionRNF180 [ NCBI-GEO ]   RNF180 [ EBI - ARRAY_EXPRESS ]   RNF180 [ SEEK ]   RNF180 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF180 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285671
GTEX Portal (Tissue expression)RNF180
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86T96   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86T96  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86T96
Splice isoforms : SwissVarQ86T96
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ86T96
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RNF180    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF180
DMDM Disease mutations285671
Blocks (Seattle)RNF180
SuperfamilyQ86T96
Human Protein AtlasENSG00000164197
Peptide AtlasQ86T96
HPRD15263
IPIIPI00784453   IPI00184160   IPI00646596   IPI00965343   
Protein Interaction databases
DIP (DOE-UCLA)Q86T96
IntAct (EBI)Q86T96
FunCoupENSG00000164197
BioGRIDRNF180
STRING (EMBL)RNF180
ZODIACRNF180
Ontologies - Pathways
QuickGOQ86T96
Ontology : AmiGOprotein polyubiquitination  intracellular  nuclear envelope  zinc ion binding  integral component of membrane  adult behavior  intrinsic component of endoplasmic reticulum membrane  positive regulation of protein ubiquitination  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  norepinephrine metabolic process  serotonin metabolic process  regulation of catalytic activity  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  intracellular  nuclear envelope  zinc ion binding  integral component of membrane  adult behavior  intrinsic component of endoplasmic reticulum membrane  positive regulation of protein ubiquitination  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  norepinephrine metabolic process  serotonin metabolic process  regulation of catalytic activity  ubiquitin protein ligase activity  
NDEx NetworkRNF180
Atlas of Cancer Signalling NetworkRNF180
Wikipedia pathwaysRNF180
Orthology - Evolution
OrthoDB285671
GeneTree (enSembl)ENSG00000164197
Phylogenetic Trees/Animal Genes : TreeFamRNF180
HOVERGENQ86T96
HOGENOMQ86T96
Homologs : HomoloGeneRNF180
Homology/Alignments : Family Browser (UCSC)RNF180
Gene fusions - Rearrangements
Fusion : MitelmanCWC27/RNF180 [5q12.3/5q12.3]  [t(5;5)(q12;q12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF180 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF180
dbVarRNF180
ClinVarRNF180
1000_GenomesRNF180 
Exome Variant ServerRNF180
ExAC (Exome Aggregation Consortium)RNF180 (select the gene name)
Genetic variants : HAPMAP285671
Genomic Variants (DGV)RNF180 [DGVbeta]
DECIPHERRNF180 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF180 
Mutations
ICGC Data PortalRNF180 
TCGA Data PortalRNF180 
Broad Tumor PortalRNF180
OASIS PortalRNF180 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF180  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF180
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF180
DgiDB (Drug Gene Interaction Database)RNF180
DoCM (Curated mutations)RNF180 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF180 (select a term)
intoGenRNF180
Cancer3DRNF180(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616015   
Orphanet
MedgenRNF180
Genetic Testing Registry RNF180
NextProtQ86T96 [Medical]
TSGene285671
GENETestsRNF180
Target ValidationRNF180
Huge Navigator RNF180 [HugePedia]
snp3D : Map Gene to Disease285671
BioCentury BCIQRNF180
ClinGenRNF180
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285671
Chemical/Pharm GKB GenePA134980027
Clinical trialRNF180
Miscellaneous
canSAR (ICR)RNF180 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF180
EVEXRNF180
GoPubMedRNF180
iHOPRNF180
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:13:12 CEST 2017

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