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RNF185 (ring finger protein 185)

Identity

Alias (NCBI)-
HGNC (Hugo) RNF185
HGNC Alias symbFLJ38628
HGNC Alias namehypothetical protein FLJ38628
LocusID (NCBI) 91445
Atlas_Id 55476
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 31160182 and ends at 31207019 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LIMS1 (2q12.3) / RNF185 (22q12.2)NKX6-3 (8p11.21) / RNF185 (22q12.2)RNF185 (22q12.2) / CFC1B (2q21.1)
RNF185 (22q12.2) / ESRRG (1q41)RNF185 (22q12.2) / ISX (22q12.3)RNF185 (22q12.2) / SMTN (22q12.2)
RNF185 (22q12.2) / STEAP2 (7q21.13)TXNRD1 (12q23.3) / RNF185 (22q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RNF185   26783
Cards
Entrez_Gene (NCBI)RNF185    ring finger protein 185
Aliases
GeneCards (Weizmann)RNF185
Ensembl hg19 (Hinxton)ENSG00000138942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138942 [Gene_View]  ENSG00000138942 [Sequence]  chr22:31160182-31207019 [Contig_View]  RNF185 [Vega]
ICGC DataPortalENSG00000138942
TCGA cBioPortalRNF185
AceView (NCBI)RNF185
Genatlas (Paris)RNF185
SOURCE (Princeton)RNF185
Genetics Home Reference (NIH)RNF185
Genomic and cartography
GoldenPath hg38 (UCSC)RNF185  -     chr22:31160182-31207019 +  22q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF185  -     22q12.2   [Description]    (hg19-Feb_2009)
GoldenPathRNF185 - 22q12.2 [CytoView hg19]  RNF185 - 22q12.2 [CytoView hg38]
ImmunoBaseENSG00000138942
Genome Data Viewer NCBIRNF185 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA258379 AK027035 AK075154 AK095947 AK291236
RefSeq transcript (Entrez)NM_001135824 NM_001135825 NM_152267
Consensus coding sequences : CCDS (NCBI)RNF185
Gene ExpressionRNF185 [ NCBI-GEO ]   RNF185 [ EBI - ARRAY_EXPRESS ]   RNF185 [ SEEK ]   RNF185 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF185 [ Firebrowse - Broad ]
GenevisibleExpression of RNF185 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91445
GTEX Portal (Tissue expression)RNF185
Human Protein AtlasENSG00000138942-RNF185 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GF1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GF1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GF1
PhosPhoSitePlusQ96GF1
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF185
SuperfamilyQ96GF1
AlphaFold pdb e-kbQ96GF1   
Human Protein Atlas [tissue]ENSG00000138942-RNF185 [tissue]
HPRD08790
Protein Interaction databases
DIP (DOE-UCLA)Q96GF1
IntAct (EBI)Q96GF1
BioGRIDRNF185
STRING (EMBL)RNF185
ZODIACRNF185
Ontologies - Pathways
QuickGOQ96GF1
Ontology : AmiGOprotein binding  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  ubiquitin-dependent protein catabolic process  autophagy  integral component of membrane  ubiquitin-dependent ERAD pathway  ERAD pathway  ubiquitin binding  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  ubiquitin-like protein conjugating enzyme binding  protein-containing complex binding  metal ion binding  protein autoubiquitination  transmembrane transport  ubiquitin protein ligase activity  ubiquitin protein ligase activity  ER-associated misfolded protein catabolic process  positive regulation of ERAD pathway  endoplasmic reticulum mannose trimming  
Ontology : EGO-EBIprotein binding  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  ubiquitin-dependent protein catabolic process  autophagy  integral component of membrane  ubiquitin-dependent ERAD pathway  ERAD pathway  ubiquitin binding  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  ubiquitin-like protein conjugating enzyme binding  protein-containing complex binding  metal ion binding  protein autoubiquitination  transmembrane transport  ubiquitin protein ligase activity  ubiquitin protein ligase activity  ER-associated misfolded protein catabolic process  positive regulation of ERAD pathway  endoplasmic reticulum mannose trimming  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkRNF185
Atlas of Cancer Signalling NetworkRNF185
Wikipedia pathwaysRNF185
Orthology - Evolution
OrthoDB91445
GeneTree (enSembl)ENSG00000138942
Phylogenetic Trees/Animal Genes : TreeFamRNF185
Homologs : HomoloGeneRNF185
Homology/Alignments : Family Browser (UCSC)RNF185
Gene fusions - Rearrangements
Fusion : QuiverRNF185
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF185 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF185
dbVarRNF185
ClinVarRNF185
MonarchRNF185
1000_GenomesRNF185 
Exome Variant ServerRNF185
GNOMAD BrowserENSG00000138942
Varsome BrowserRNF185
ACMGRNF185 variants
VarityQ96GF1
Genomic Variants (DGV)RNF185 [DGVbeta]
DECIPHERRNF185 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF185 
Mutations
ICGC Data PortalRNF185 
TCGA Data PortalRNF185 
Broad Tumor PortalRNF185
OASIS PortalRNF185 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF185  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF185
Mutations and Diseases : HGMDRNF185
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRNF185
DgiDB (Drug Gene Interaction Database)RNF185
DoCM (Curated mutations)RNF185
CIViC (Clinical Interpretations of Variants in Cancer)RNF185
Cancer3DRNF185
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRNF185
MedgenRNF185
Genetic Testing Registry RNF185
NextProtQ96GF1 [Medical]
GENETestsRNF185
Target ValidationRNF185
Huge Navigator RNF185 [HugePedia]
ClinGenRNF185
Clinical trials, drugs, therapy
MyCancerGenomeRNF185
Protein Interactions : CTDRNF185
Pharm GKB GenePA142671056
PharosQ96GF1
Clinical trialRNF185
Miscellaneous
canSAR (ICR)RNF185
HarmonizomeRNF185
DataMed IndexRNF185
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRNF185
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:14 CEST 2021

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