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RNF185 (ring finger protein 185)

Identity

Alias_symbol (synonym)FLJ38628
Other alias-
HGNC (Hugo) RNF185
LocusID (NCBI) 91445
Atlas_Id 55476
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 31160152 and ends at 31207019 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LIMS1 (2q12.3) / RNF185 (22q12.2)NKX6-3 (8p11.21) / RNF185 (22q12.2)RNF185 (22q12.2) / CFC1B (2q21.1)
RNF185 (22q12.2) / ESRRG (1q41)RNF185 (22q12.2) / ISX (22q12.3)RNF185 (22q12.2) / SMTN (22q12.2)
RNF185 (22q12.2) / STEAP2 (7q21.13)TXNRD1 (12q23.3) / RNF185 (22q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF185   26783
Cards
Entrez_Gene (NCBI)RNF185  91445  ring finger protein 185
Aliases
GeneCards (Weizmann)RNF185
Ensembl hg19 (Hinxton)ENSG00000138942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138942 [Gene_View]  chr22:31160152-31207019 [Contig_View]  RNF185 [Vega]
ICGC DataPortalENSG00000138942
TCGA cBioPortalRNF185
AceView (NCBI)RNF185
Genatlas (Paris)RNF185
WikiGenes91445
SOURCE (Princeton)RNF185
Genetics Home Reference (NIH)RNF185
Genomic and cartography
GoldenPath hg38 (UCSC)RNF185  -     chr22:31160152-31207019 +  22q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF185  -     22q12.2   [Description]    (hg19-Feb_2009)
EnsemblRNF185 - 22q12.2 [CytoView hg19]  RNF185 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBIRNF185 [Mapview hg19]  RNF185 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA258379 AK027035 AK075154 AK095947 AK291236
RefSeq transcript (Entrez)NM_001135824 NM_001135825 NM_152267
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF185
Cluster EST : UnigeneHs.517553 [ NCBI ]
CGAP (NCI)Hs.517553
Alternative Splicing GalleryENSG00000138942
Gene ExpressionRNF185 [ NCBI-GEO ]   RNF185 [ EBI - ARRAY_EXPRESS ]   RNF185 [ SEEK ]   RNF185 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF185 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91445
GTEX Portal (Tissue expression)RNF185
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GF1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GF1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GF1
Splice isoforms : SwissVarQ96GF1
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ96GF1
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF185
DMDM Disease mutations91445
Blocks (Seattle)RNF185
SuperfamilyQ96GF1
Human Protein AtlasENSG00000138942
Peptide AtlasQ96GF1
HPRD08790
IPIIPI00435433   IPI00182628   IPI00883999   IPI00883820   IPI00909662   
Protein Interaction databases
DIP (DOE-UCLA)Q96GF1
IntAct (EBI)Q96GF1
FunCoupENSG00000138942
BioGRIDRNF185
STRING (EMBL)RNF185
ZODIACRNF185
Ontologies - Pathways
QuickGOQ96GF1
Ontology : AmiGOprotein binding  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  autophagy  zinc ion binding  integral component of membrane  ubiquitin-dependent ERAD pathway  ERAD pathway  Derlin-1 retrotranslocation complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  protein autoubiquitination  transmembrane transport  ER-associated misfolded protein catabolic process  ubiquitin protein ligase activity involved in ERAD pathway  ubiquitin protein ligase activity involved in ERAD pathway  endoplasmic reticulum mannose trimming  
Ontology : EGO-EBIprotein binding  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  autophagy  zinc ion binding  integral component of membrane  ubiquitin-dependent ERAD pathway  ERAD pathway  Derlin-1 retrotranslocation complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin-like protein conjugating enzyme binding  protein autoubiquitination  transmembrane transport  ER-associated misfolded protein catabolic process  ubiquitin protein ligase activity involved in ERAD pathway  ubiquitin protein ligase activity involved in ERAD pathway  endoplasmic reticulum mannose trimming  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkRNF185
Atlas of Cancer Signalling NetworkRNF185
Wikipedia pathwaysRNF185
Orthology - Evolution
OrthoDB91445
GeneTree (enSembl)ENSG00000138942
Phylogenetic Trees/Animal Genes : TreeFamRNF185
HOVERGENQ96GF1
HOGENOMQ96GF1
Homologs : HomoloGeneRNF185
Homology/Alignments : Family Browser (UCSC)RNF185
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF185 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF185
dbVarRNF185
ClinVarRNF185
1000_GenomesRNF185 
Exome Variant ServerRNF185
ExAC (Exome Aggregation Consortium)RNF185 (select the gene name)
Genetic variants : HAPMAP91445
Genomic Variants (DGV)RNF185 [DGVbeta]
DECIPHERRNF185 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF185 
Mutations
ICGC Data PortalRNF185 
TCGA Data PortalRNF185 
Broad Tumor PortalRNF185
OASIS PortalRNF185 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF185  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF185
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF185
DgiDB (Drug Gene Interaction Database)RNF185
DoCM (Curated mutations)RNF185 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF185 (select a term)
intoGenRNF185
Cancer3DRNF185(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRNF185
Genetic Testing Registry RNF185
NextProtQ96GF1 [Medical]
TSGene91445
GENETestsRNF185
Huge Navigator RNF185 [HugePedia]
snp3D : Map Gene to Disease91445
BioCentury BCIQRNF185
ClinGenRNF185
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD91445
Chemical/Pharm GKB GenePA142671056
Clinical trialRNF185
Miscellaneous
canSAR (ICR)RNF185 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF185
EVEXRNF185
GoPubMedRNF185
iHOPRNF185
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:35:16 CEST 2017

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