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RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase)

Identity

Alias_namesRNF19
ring finger protein 19
ring finger protein 19A
ring finger protein 19A, E3 ubiquitin protein ligase
Alias_symbol (synonym)dorfin
DKFZp566B1346
Other alias
HGNC (Hugo) RNF19A
LocusID (NCBI) 25897
Atlas_Id 47168
Location 8q22.2  [Link to chromosome band 8q22]
Location_base_pair Starts at 101269287 and ends at 101348446 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AZIN1 (8q22.3) / RNF19A (8q22.2)NIPAL2 (8q22.2) / RNF19A (8q22.2)RNF19A (8q22.2) / ANKRD46 (8q22.2)
RNF19A (8q22.2) / PRSS3 (9p13.3)RNF19A (8q22.2) / RALYL (8q21.2)RNF19A (8q22.2) / RIDA (8q22.2)
RNF19A (8q22.2) / RNF19A (8q22.2)RNF19A (8q22.2) / SLC41A3 (3q21.2)RNF19A (8q22.2) / SNX31 (8q22.2)
RNF19A (8q22.2) / STAU2 (8q21.11)RNF19A (8q22.2) / STK3 (8q22.2)RNF19A (8q22.2) / STRAP (12p12.3)
RNF19A (8q22.2) / TRIQK (8q22.1)AZIN1 8q22.3 / RNF19A 8q22.2NIPAL2 8q22.2 / RNF19A 8q22.2
RNF19A 8q22.2 / ANKRD46 8q22.2RNF19A 8q22.2 C8orf83RNF19A 8q22.2 / HRSP12 8q22.2
RNF19A 8q22.2 / PRSS3 9p13.3RNF19A 8q22.2 / RALYL 8q21.2RNF19A 8q22.2 / SLC41A3 3q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF19A   13432
Cards
Entrez_Gene (NCBI)RNF19A  25897  ring finger protein 19A, RBR E3 ubiquitin protein ligase
AliasesRNF19
GeneCards (Weizmann)RNF19A
Ensembl hg19 (Hinxton)ENSG00000034677 [Gene_View]  chr8:101269287-101348446 [Contig_View]  RNF19A [Vega]
Ensembl hg38 (Hinxton)ENSG00000034677 [Gene_View]  chr8:101269287-101348446 [Contig_View]  RNF19A [Vega]
ICGC DataPortalENSG00000034677
TCGA cBioPortalRNF19A
AceView (NCBI)RNF19A
Genatlas (Paris)RNF19A
WikiGenes25897
SOURCE (Princeton)RNF19A
Genetics Home Reference (NIH)RNF19A
Genomic and cartography
GoldenPath hg19 (UCSC)RNF19A  -     chr8:101269287-101348446 -  8q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RNF19A  -     8q22.2   [Description]    (hg38-Dec_2013)
EnsemblRNF19A - 8q22.2 [CytoView hg19]  RNF19A - 8q22.2 [CytoView hg38]
Mapping of homologs : NCBIRNF19A [Mapview hg19]  RNF19A [Mapview hg38]
OMIM607119   
Gene and transcription
Genbank (Entrez)AB029316 AB271913 AB271914 AJ242975 AK023455
RefSeq transcript (Entrez)NM_001280539 NM_015435 NM_183419
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)RNF19A
Cluster EST : UnigeneHs.292882 [ NCBI ]
CGAP (NCI)Hs.292882
Alternative Splicing GalleryENSG00000034677
Gene ExpressionRNF19A [ NCBI-GEO ]   RNF19A [ EBI - ARRAY_EXPRESS ]   RNF19A [ SEEK ]   RNF19A [ MEM ]
Gene Expression Viewer (FireBrowse)RNF19A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25897
GTEX Portal (Tissue expression)RNF19A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NV58   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NV58  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NV58
Splice isoforms : SwissVarQ9NV58
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9NV58
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)E3_UB_ligase_RBR    IBR_dom    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)IBR (PF01485)   
Domain families : Pfam (NCBI)pfam01485   
Domain families : Smart (EMBL)IBR (SM00647)  RING (SM00184)  
Conserved Domain (NCBI)RNF19A
DMDM Disease mutations25897
Blocks (Seattle)RNF19A
SuperfamilyQ9NV58
Human Protein AtlasENSG00000034677
Peptide AtlasQ9NV58
HPRD06176
IPIIPI00019056   IPI00793570   IPI00869122   IPI00816302   IPI00979497   IPI01015473   IPI00977316   IPI00976767   IPI00976182   IPI00984246   
Protein Interaction databases
DIP (DOE-UCLA)Q9NV58
IntAct (EBI)Q9NV58
FunCoupENSG00000034677
BioGRIDRNF19A
STRING (EMBL)RNF19A
ZODIACRNF19A
Ontologies - Pathways
QuickGOQ9NV58
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  microtubule cytoskeleton organization  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytoplasm  centrosome  cytosol  transcription factor binding  zinc ion binding  integral component of membrane  ligase activity  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  microtubule cytoskeleton organization  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytoplasm  centrosome  cytosol  transcription factor binding  zinc ion binding  integral component of membrane  ligase activity  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  
NDEx NetworkRNF19A
Atlas of Cancer Signalling NetworkRNF19A
Wikipedia pathwaysRNF19A
Orthology - Evolution
OrthoDB25897
GeneTree (enSembl)ENSG00000034677
Phylogenetic Trees/Animal Genes : TreeFamRNF19A
HOVERGENQ9NV58
HOGENOMQ9NV58
Homologs : HomoloGeneRNF19A
Homology/Alignments : Family Browser (UCSC)RNF19A
Gene fusions - Rearrangements
Fusion : MitelmanAZIN1/RNF19A [8q22.3/8q22.2]  [t(8;8)(q22;q22)]  
Fusion : MitelmanNIPAL2/RNF19A [8q22.2/8q22.2]  [t(8;8)(q22;q22)]  
Fusion : MitelmanRNF19A/ANKRD46 [8q22.2/8q22.2]  [t(8;8)(q22;q22)]  
Fusion : MitelmanRNF19A/HRSP12 [8q22.2/8q22.2]  [t(8;8)(q22;q22)]  
Fusion : MitelmanRNF19A/PRSS3 [8q22.2/9p13.3]  [t(8;9)(q22;p13)]  
Fusion : MitelmanRNF19A/RALYL [8q22.2/8q21.2]  [t(8;8)(q21;q22)]  
Fusion : MitelmanRNF19A/SLC41A3 [8q22.2/3q21.2]  [t(3;8)(q21;q22)]  
Fusion : MitelmanRNF19A/SNX31 [8q22.2/8q22.2]  [t(8;8)(q22;q22)]  
Fusion : MitelmanRNF19A/TRIQK [8q22.2/8q22.1]  [t(8;8)(q22;q22)]  
Fusion: TCGAAZIN1 8q22.3 RNF19A 8q22.2 SKCM
Fusion: TCGANIPAL2 8q22.2 RNF19A 8q22.2 BRCA
Fusion: TCGARNF19A 8q22.2 ANKRD46 8q22.2 BLCA LUSC
Fusion: TCGARNF19A 8q22.2 C8orf83 LUSC
Fusion: TCGARNF19A 8q22.2 HRSP12 8q22.2 BRCA
Fusion: TCGARNF19A 8q22.2 PRSS3 9p13.3 LUSC
Fusion: TCGARNF19A 8q22.2 RALYL 8q21.2 BRCA
Fusion: TCGARNF19A 8q22.2 SLC41A3 3q21.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF19A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF19A
dbVarRNF19A
ClinVarRNF19A
1000_GenomesRNF19A 
Exome Variant ServerRNF19A
ExAC (Exome Aggregation Consortium)RNF19A (select the gene name)
Genetic variants : HAPMAP25897
Genomic Variants (DGV)RNF19A [DGVbeta]
DECIPHER (Syndromes)8:101269287-101348446  ENSG00000034677
CONAN: Copy Number AnalysisRNF19A 
Mutations
ICGC Data PortalRNF19A 
TCGA Data PortalRNF19A 
Broad Tumor PortalRNF19A
OASIS PortalRNF19A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF19A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF19A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF19A
DgiDB (Drug Gene Interaction Database)RNF19A
DoCM (Curated mutations)RNF19A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF19A (select a term)
intoGenRNF19A
Cancer3DRNF19A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607119   
Orphanet
MedgenRNF19A
Genetic Testing Registry RNF19A
NextProtQ9NV58 [Medical]
TSGene25897
GENETestsRNF19A
Huge Navigator RNF19A [HugePedia]
snp3D : Map Gene to Disease25897
BioCentury BCIQRNF19A
ClinGenRNF19A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25897
Chemical/Pharm GKB GenePA162401601
Clinical trialRNF19A
Miscellaneous
canSAR (ICR)RNF19A (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF19A
EVEXRNF19A
GoPubMedRNF19A
iHOPRNF19A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:42 CEST 2017

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