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RNF19B (ring finger protein 19B)

Identity

Alias_namesIBRDC3
IBR domain containing 3
Alias_symbol (synonym)FLJ90005
Other aliasNKLAM
HGNC (Hugo) RNF19B
LocusID (NCBI) 127544
Atlas_Id 72699
Location 1p35.1  [Link to chromosome band 1p35]
Location_base_pair Starts at 32936446 and ends at 32964813 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADCY2 (5p15.31) / RNF19B (1p35.1)RNF19B (1p35.1) / PRR27 (4q13.3)YARS (1p35.1) / RNF19B (1p35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF19B   26886
Cards
Entrez_Gene (NCBI)RNF19B  127544  ring finger protein 19B
AliasesIBRDC3; NKLAM
GeneCards (Weizmann)RNF19B
Ensembl hg19 (Hinxton)ENSG00000116514 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116514 [Gene_View]  chr1:32936446-32964813 [Contig_View]  RNF19B [Vega]
ICGC DataPortalENSG00000116514
TCGA cBioPortalRNF19B
AceView (NCBI)RNF19B
Genatlas (Paris)RNF19B
WikiGenes127544
SOURCE (Princeton)RNF19B
Genetics Home Reference (NIH)RNF19B
Genomic and cartography
GoldenPath hg38 (UCSC)RNF19B  -     chr1:32936446-32964813 -  1p35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF19B  -     1p35.1   [Description]    (hg19-Feb_2009)
EnsemblRNF19B - 1p35.1 [CytoView hg19]  RNF19B - 1p35.1 [CytoView hg38]
Mapping of homologs : NCBIRNF19B [Mapview hg19]  RNF19B [Mapview hg38]
OMIM610872   
Gene and transcription
Genbank (Entrez)AA194237 AK074486 AK131439 BC020595 BC062374
RefSeq transcript (Entrez)NM_001127361 NM_001300826 NM_153341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF19B
Cluster EST : UnigeneHs.591504 [ NCBI ]
CGAP (NCI)Hs.591504
Alternative Splicing GalleryENSG00000116514
Gene ExpressionRNF19B [ NCBI-GEO ]   RNF19B [ EBI - ARRAY_EXPRESS ]   RNF19B [ SEEK ]   RNF19B [ MEM ]
Gene Expression Viewer (FireBrowse)RNF19B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)127544
GTEX Portal (Tissue expression)RNF19B
Human Protein AtlasENSG00000116514-RNF19B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMZ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMZ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMZ0
Splice isoforms : SwissVarQ6ZMZ0
PhosPhoSitePlusQ6ZMZ0
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)E3_UB_ligase_RBR    IBR_dom    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)IBR (PF01485)   
Domain families : Pfam (NCBI)pfam01485   
Domain families : Smart (EMBL)IBR (SM00647)  RING (SM00184)  
Conserved Domain (NCBI)RNF19B
DMDM Disease mutations127544
Blocks (Seattle)RNF19B
SuperfamilyQ6ZMZ0
Human Protein Atlas [tissue]ENSG00000116514-RNF19B [tissue]
Peptide AtlasQ6ZMZ0
HPRD13725
IPIIPI00477479   IPI00514163   IPI00868770   IPI00868849   IPI00974255   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMZ0
IntAct (EBI)Q6ZMZ0
FunCoupENSG00000116514
BioGRIDRNF19B
STRING (EMBL)RNF19B
ZODIACRNF19B
Ontologies - Pathways
QuickGOQ6ZMZ0
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  adaptive immune response  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  cytosol  zinc ion binding  integral component of membrane  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  cytolytic granule  ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  adaptive immune response  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  cytosol  zinc ion binding  integral component of membrane  ubiquitin conjugating enzyme binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  cytolytic granule  ubiquitin protein ligase activity  
NDEx NetworkRNF19B
Atlas of Cancer Signalling NetworkRNF19B
Wikipedia pathwaysRNF19B
Orthology - Evolution
OrthoDB127544
GeneTree (enSembl)ENSG00000116514
Phylogenetic Trees/Animal Genes : TreeFamRNF19B
HOVERGENQ6ZMZ0
HOGENOMQ6ZMZ0
Homologs : HomoloGeneRNF19B
Homology/Alignments : Family Browser (UCSC)RNF19B
Gene fusions - Rearrangements
Fusion: Tumor Portal RNF19B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF19B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF19B
dbVarRNF19B
ClinVarRNF19B
1000_GenomesRNF19B 
Exome Variant ServerRNF19B
ExAC (Exome Aggregation Consortium)ENSG00000116514
GNOMAD BrowserENSG00000116514
Genetic variants : HAPMAP127544
Genomic Variants (DGV)RNF19B [DGVbeta]
DECIPHERRNF19B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF19B 
Mutations
ICGC Data PortalRNF19B 
TCGA Data PortalRNF19B 
Broad Tumor PortalRNF19B
OASIS PortalRNF19B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF19B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF19B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF19B
DgiDB (Drug Gene Interaction Database)RNF19B
DoCM (Curated mutations)RNF19B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF19B (select a term)
intoGenRNF19B
Cancer3DRNF19B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610872   
Orphanet
MedgenRNF19B
Genetic Testing Registry RNF19B
NextProtQ6ZMZ0 [Medical]
TSGene127544
GENETestsRNF19B
Target ValidationRNF19B
Huge Navigator RNF19B [HugePedia]
snp3D : Map Gene to Disease127544
BioCentury BCIQRNF19B
ClinGenRNF19B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD127544
Chemical/Pharm GKB GenePA162401626
Clinical trialRNF19B
Miscellaneous
canSAR (ICR)RNF19B (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF19B
EVEXRNF19B
GoPubMedRNF19B
iHOPRNF19B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:25:15 CET 2017

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