Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RNF215 (ring finger protein 215)

Identity

Alias (NCBI)-
HGNC (Hugo) RNF215
LocusID (NCBI) 200312
Atlas_Id 72704
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 30378814 and ends at 30387313 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTMR3 (22q12.2) / RNF215 (22q12.2)RNF215 (22q12.2) / GRIN2B (12p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(12;22)(p13;q12) RNF215/GRIN2B
MTMR3/RNF215 (22q12)

External links

Nomenclature
HGNC (Hugo)RNF215   33434
Cards
Entrez_Gene (NCBI)RNF215  200312  ring finger protein 215
Aliases
GeneCards (Weizmann)RNF215
Ensembl hg19 (Hinxton)ENSG00000099999 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099999 [Gene_View]  ENSG00000099999 [Sequence]  chr22:30378814-30387313 [Contig_View]  RNF215 [Vega]
ICGC DataPortalENSG00000099999
TCGA cBioPortalRNF215
AceView (NCBI)RNF215
Genatlas (Paris)RNF215
WikiGenes200312
SOURCE (Princeton)RNF215
Genetics Home Reference (NIH)RNF215
Genomic and cartography
GoldenPath hg38 (UCSC)RNF215  -     chr22:30378814-30387313 -  22q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF215  -     22q12.2   [Description]    (hg19-Feb_2009)
GoldenPathRNF215 - 22q12.2 [CytoView hg19]  RNF215 - 22q12.2 [CytoView hg38]
ImmunoBaseENSG00000099999
genome Data Viewer NCBIRNF215 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK293904 BM476400 BM806918 BX494669
RefSeq transcript (Entrez)NM_001017981
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF215
Alternative Splicing GalleryENSG00000099999
Gene ExpressionRNF215 [ NCBI-GEO ]   RNF215 [ EBI - ARRAY_EXPRESS ]   RNF215 [ SEEK ]   RNF215 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF215 [ Firebrowse - Broad ]
GenevisibleExpression of RNF215 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)200312
GTEX Portal (Tissue expression)RNF215
Human Protein AtlasENSG00000099999-RNF215 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6U7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6U7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6U7
Splice isoforms : SwissVarQ9Y6U7
PhosPhoSitePlusQ9Y6U7
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF215
DMDM Disease mutations200312
Blocks (Seattle)RNF215
SuperfamilyQ9Y6U7
Human Protein Atlas [tissue]ENSG00000099999-RNF215 [tissue]
Peptide AtlasQ9Y6U7
HPRD18747
IPIIPI00164063   IPI00879230   IPI00746440   IPI00916661   IPI00916275   IPI00915968   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6U7
IntAct (EBI)Q9Y6U7
FunCoupENSG00000099999
BioGRIDRNF215
STRING (EMBL)RNF215
ZODIACRNF215
Ontologies - Pathways
QuickGOQ9Y6U7
Ontology : AmiGOnucleus  cytoplasm  late endosome  Golgi apparatus  ubiquitin-dependent protein catabolic process  integral component of membrane  protein ubiquitination  metal ion binding  response to misfolded protein  ubiquitin protein ligase activity  
Ontology : EGO-EBInucleus  cytoplasm  late endosome  Golgi apparatus  ubiquitin-dependent protein catabolic process  integral component of membrane  protein ubiquitination  metal ion binding  response to misfolded protein  ubiquitin protein ligase activity  
NDEx NetworkRNF215
Atlas of Cancer Signalling NetworkRNF215
Wikipedia pathwaysRNF215
Orthology - Evolution
OrthoDB200312
GeneTree (enSembl)ENSG00000099999
Phylogenetic Trees/Animal Genes : TreeFamRNF215
HOGENOMQ9Y6U7
Homologs : HomoloGeneRNF215
Homology/Alignments : Family Browser (UCSC)RNF215
Gene fusions - Rearrangements
Fusion : QuiverRNF215
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF215 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF215
dbVarRNF215
ClinVarRNF215
1000_GenomesRNF215 
Exome Variant ServerRNF215
GNOMAD BrowserENSG00000099999
Varsome BrowserRNF215
Genetic variants : HAPMAP200312
Genomic Variants (DGV)RNF215 [DGVbeta]
DECIPHERRNF215 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF215 
Mutations
ICGC Data PortalRNF215 
TCGA Data PortalRNF215 
Broad Tumor PortalRNF215
OASIS PortalRNF215 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF215  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRNF215
Mutations and Diseases : HGMDRNF215
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF215
DgiDB (Drug Gene Interaction Database)RNF215
DoCM (Curated mutations)RNF215 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF215 (select a term)
intoGenRNF215
Cancer3DRNF215(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETRNF215
MedgenRNF215
Genetic Testing Registry RNF215
NextProtQ9Y6U7 [Medical]
TSGene200312
GENETestsRNF215
Target ValidationRNF215
Huge Navigator RNF215 [HugePedia]
snp3D : Map Gene to Disease200312
BioCentury BCIQRNF215
ClinGenRNF215
Clinical trials, drugs, therapy
Protein Interactions : CTD200312
Pharm GKB GenePA162401807
Clinical trialRNF215
Miscellaneous
canSAR (ICR)RNF215 (select the gene name)
HarmonizomeRNF215
DataMed IndexRNF215
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF215
EVEXRNF215
GoPubMedRNF215
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:25:39 CEST 2020
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