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RNF25 (ring finger protein 25)

Identity

Alias_symbol (synonym)AO7
FLJ13906
Other alias
HGNC (Hugo) RNF25
LocusID (NCBI) 64320
Atlas_Id 47140
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 219528587 and ends at 219536781 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TMEM184B (22q13.1) / RNF25 (2q35)USP37 (2q35) / RNF25 (2q35)TMEM184B 22q13.1 / RNF25 2q35
USP37 2q35 / RNF25 2q35

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF25   14662
Cards
Entrez_Gene (NCBI)RNF25  64320  ring finger protein 25
AliasesAO7
GeneCards (Weizmann)RNF25
Ensembl hg19 (Hinxton)ENSG00000163481 [Gene_View]  chr2:219528587-219536781 [Contig_View]  RNF25 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163481 [Gene_View]  chr2:219528587-219536781 [Contig_View]  RNF25 [Vega]
ICGC DataPortalENSG00000163481
TCGA cBioPortalRNF25
AceView (NCBI)RNF25
Genatlas (Paris)RNF25
WikiGenes64320
SOURCE (Princeton)RNF25
Genetics Home Reference (NIH)RNF25
Genomic and cartography
GoldenPath hg19 (UCSC)RNF25  -     chr2:219528587-219536781 -  2q35   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RNF25  -     2q35   [Description]    (hg38-Dec_2013)
EnsemblRNF25 - 2q35 [CytoView hg19]  RNF25 - 2q35 [CytoView hg38]
Mapping of homologs : NCBIRNF25 [Mapview hg19]  RNF25 [Mapview hg38]
OMIM616014   
Gene and transcription
Genbank (Entrez)AK023968 AK222525 AK289501 AW613024 BC015612
RefSeq transcript (Entrez)NM_022453
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)RNF25
Cluster EST : UnigeneHs.471403 [ NCBI ]
CGAP (NCI)Hs.471403
Alternative Splicing GalleryENSG00000163481
Gene ExpressionRNF25 [ NCBI-GEO ]   RNF25 [ EBI - ARRAY_EXPRESS ]   RNF25 [ SEEK ]   RNF25 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64320
GTEX Portal (Tissue expression)RNF25
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96BH1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96BH1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96BH1
Splice isoforms : SwissVarQ96BH1
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ96BH1
Domaine pattern : Prosite (Expaxy)RWD (PS50908)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RWD-domain    UBQ-conjugating_enzyme/RWD    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RWD (PF05773)    zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam05773    pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  RWD (SM00591)  
Conserved Domain (NCBI)RNF25
DMDM Disease mutations64320
Blocks (Seattle)RNF25
PDB (SRS)2DAY    2DMF    5D1K    5D1L    5D1M   
PDB (PDBSum)2DAY    2DMF    5D1K    5D1L    5D1M   
PDB (IMB)2DAY    2DMF    5D1K    5D1L    5D1M   
PDB (RSDB)2DAY    2DMF    5D1K    5D1L    5D1M   
Structural Biology KnowledgeBase2DAY    2DMF    5D1K    5D1L    5D1M   
SCOP (Structural Classification of Proteins)2DAY    2DMF    5D1K    5D1L    5D1M   
CATH (Classification of proteins structures)2DAY    2DMF    5D1K    5D1L    5D1M   
SuperfamilyQ96BH1
Human Protein AtlasENSG00000163481
Peptide AtlasQ96BH1
HPRD09737
IPIIPI00059944   IPI00926386   
Protein Interaction databases
DIP (DOE-UCLA)Q96BH1
IntAct (EBI)Q96BH1
FunCoupENSG00000163481
BioGRIDRNF25
STRING (EMBL)RNF25
ZODIACRNF25
Ontologies - Pathways
QuickGOQ96BH1
Ontology : AmiGOubiquitin-protein transferase activity  nucleus  cytosol  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  NF-kappaB binding  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  
Ontology : EGO-EBIubiquitin-protein transferase activity  nucleus  cytosol  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  NF-kappaB binding  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  
NDEx NetworkRNF25
Atlas of Cancer Signalling NetworkRNF25
Wikipedia pathwaysRNF25
Orthology - Evolution
OrthoDB64320
GeneTree (enSembl)ENSG00000163481
Phylogenetic Trees/Animal Genes : TreeFamRNF25
HOVERGENQ96BH1
HOGENOMQ96BH1
Homologs : HomoloGeneRNF25
Homology/Alignments : Family Browser (UCSC)RNF25
Gene fusions - Rearrangements
Fusion : MitelmanTMEM184B/RNF25 [22q13.1/2q35]  [t(2;22)(q35;q13)]  
Fusion: TCGATMEM184B 22q13.1 RNF25 2q35 BRCA
Fusion: TCGAUSP37 2q35 RNF25 2q35 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF25
dbVarRNF25
ClinVarRNF25
1000_GenomesRNF25 
Exome Variant ServerRNF25
ExAC (Exome Aggregation Consortium)RNF25 (select the gene name)
Genetic variants : HAPMAP64320
Genomic Variants (DGV)RNF25 [DGVbeta]
DECIPHER (Syndromes)2:219528587-219536781  ENSG00000163481
CONAN: Copy Number AnalysisRNF25 
Mutations
ICGC Data PortalRNF25 
TCGA Data PortalRNF25 
Broad Tumor PortalRNF25
OASIS PortalRNF25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF25
DgiDB (Drug Gene Interaction Database)RNF25
DoCM (Curated mutations)RNF25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF25 (select a term)
intoGenRNF25
Cancer3DRNF25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616014   
Orphanet
MedgenRNF25
Genetic Testing Registry RNF25
NextProtQ96BH1 [Medical]
TSGene64320
GENETestsRNF25
Huge Navigator RNF25 [HugePedia]
snp3D : Map Gene to Disease64320
BioCentury BCIQRNF25
ClinGenRNF25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64320
Chemical/Pharm GKB GenePA34429
Clinical trialRNF25
Miscellaneous
canSAR (ICR)RNF25 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF25
EVEXRNF25
GoPubMedRNF25
iHOPRNF25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:17:43 CEST 2017

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