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RNF31 (ring finger protein 31)

Identity

Alias_symbol (synonym)ZIBRA
FLJ10111
FLJ23501
HOIP
Other alias
HGNC (Hugo) RNF31
LocusID (NCBI) 55072
Atlas_Id 46497
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24616084 and ends at 24629870 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARID1A (1p36.11) / RNF31 (14q12)DANCR (4q12) / RNF31 (14q12)HSP90AA1 (14q32.31) / RNF31 (14q12)
ARID1A 1p36.11 / RNF31 14q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF31   16031
Cards
Entrez_Gene (NCBI)RNF31  55072  ring finger protein 31
AliasesHOIP; ZIBRA
GeneCards (Weizmann)RNF31
Ensembl hg19 (Hinxton)ENSG00000092098 [Gene_View]  chr14:24616084-24629870 [Contig_View]  RNF31 [Vega]
Ensembl hg38 (Hinxton)ENSG00000092098 [Gene_View]  chr14:24616084-24629870 [Contig_View]  RNF31 [Vega]
ICGC DataPortalENSG00000092098
TCGA cBioPortalRNF31
AceView (NCBI)RNF31
Genatlas (Paris)RNF31
WikiGenes55072
SOURCE (Princeton)RNF31
Genetics Home Reference (NIH)RNF31
Genomic and cartography
GoldenPath hg19 (UCSC)RNF31  -     chr14:24616084-24629870 +  14q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RNF31  -     14q12   [Description]    (hg38-Dec_2013)
EnsemblRNF31 - 14q12 [CytoView hg19]  RNF31 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIRNF31 [Mapview hg19]  RNF31 [Mapview hg38]
OMIM612487   
Gene and transcription
Genbank (Entrez)AB265810 AK000973 AK027154 AK055542 AK122711
RefSeq transcript (Entrez)NM_001310332 NM_017999
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_042234 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)RNF31
Cluster EST : UnigeneHs.434081 [ NCBI ]
CGAP (NCI)Hs.434081
Alternative Splicing GalleryENSG00000092098
Gene ExpressionRNF31 [ NCBI-GEO ]   RNF31 [ EBI - ARRAY_EXPRESS ]   RNF31 [ SEEK ]   RNF31 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF31 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55072
GTEX Portal (Tissue expression)RNF31
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96EP0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96EP0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96EP0
Splice isoforms : SwissVarQ96EP0
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ96EP0
Domaine pattern : Prosite (Expaxy)UBA (PS50030)    ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)    ZF_RING_1 (PS00518)   
Domains : Interpro (EBI)IBR_dom    PUB_domain    RNF31    RNF31-UBA    UBA    UBA-like    Znf_RanBP2    Znf_RING    Znf_RING_CS   
Domain families : Pfam (Sanger)HOIP-UBA (PF16678)    IBR (PF01485)    PUB (PF09409)   
Domain families : Pfam (NCBI)pfam16678    pfam01485    pfam09409   
Domain families : Smart (EMBL)IBR (SM00647)  RING (SM00184)  ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)RNF31
DMDM Disease mutations55072
Blocks (Seattle)RNF31
PDB (SRS)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
PDB (PDBSum)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
PDB (IMB)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
PDB (RSDB)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
Structural Biology KnowledgeBase2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
SCOP (Structural Classification of Proteins)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
CATH (Classification of proteins structures)2CT7    4DBG    4JUY    4LJO    4LJP    4LJQ    4OWF    4OYJ    4OYK    4P09    4P0A    4P0B    5EDV   
SuperfamilyQ96EP0
Human Protein AtlasENSG00000092098
Peptide AtlasQ96EP0
HPRD11516
IPIIPI00094740   IPI00409629   IPI00604409   IPI00952713   
Protein Interaction databases
DIP (DOE-UCLA)Q96EP0
IntAct (EBI)Q96EP0
FunCoupENSG00000092098
BioGRIDRNF31
STRING (EMBL)RNF31
ZODIACRNF31
Ontologies - Pathways
QuickGOQ96EP0
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytosol  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  cytoplasmic side of plasma membrane  regulation of tumor necrosis factor-mediated signaling pathway  ligase activity  CD40 signaling pathway  ubiquitin protein ligase binding  CD40 receptor complex  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin binding  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  LUBAC complex  protein linear polyubiquitination  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  cytosol  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  cytoplasmic side of plasma membrane  regulation of tumor necrosis factor-mediated signaling pathway  ligase activity  CD40 signaling pathway  ubiquitin protein ligase binding  CD40 receptor complex  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin binding  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  LUBAC complex  protein linear polyubiquitination  positive regulation of protein targeting to mitochondrion  
NDEx NetworkRNF31
Atlas of Cancer Signalling NetworkRNF31
Wikipedia pathwaysRNF31
Orthology - Evolution
OrthoDB55072
GeneTree (enSembl)ENSG00000092098
Phylogenetic Trees/Animal Genes : TreeFamRNF31
HOVERGENQ96EP0
HOGENOMQ96EP0
Homologs : HomoloGeneRNF31
Homology/Alignments : Family Browser (UCSC)RNF31
Gene fusions - Rearrangements
Fusion : MitelmanARID1A/RNF31 [1p36.11/14q12]  [t(1;14)(p36;q12)]  
Fusion: TCGAARID1A 1p36.11 RNF31 14q12 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF31 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF31
dbVarRNF31
ClinVarRNF31
1000_GenomesRNF31 
Exome Variant ServerRNF31
ExAC (Exome Aggregation Consortium)RNF31 (select the gene name)
Genetic variants : HAPMAP55072
Genomic Variants (DGV)RNF31 [DGVbeta]
DECIPHER (Syndromes)14:24616084-24629870  ENSG00000092098
CONAN: Copy Number AnalysisRNF31 
Mutations
ICGC Data PortalRNF31 
TCGA Data PortalRNF31 
Broad Tumor PortalRNF31
OASIS PortalRNF31 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF31  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF31
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF31
DgiDB (Drug Gene Interaction Database)RNF31
DoCM (Curated mutations)RNF31 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF31 (select a term)
intoGenRNF31
Cancer3DRNF31(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612487   
Orphanet21903   
MedgenRNF31
Genetic Testing Registry RNF31
NextProtQ96EP0 [Medical]
TSGene55072
GENETestsRNF31
Huge Navigator RNF31 [HugePedia]
snp3D : Map Gene to Disease55072
BioCentury BCIQRNF31
ClinGenRNF31
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55072
Chemical/Pharm GKB GenePA134906471
Clinical trialRNF31
Miscellaneous
canSAR (ICR)RNF31 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF31
EVEXRNF31
GoPubMedRNF31
iHOPRNF31
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:25:24 CET 2017

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