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RNF41 (ring finger protein 41)

Identity

Alias_namesring finger protein 41
Alias_symbol (synonym)SBBI03
NRDP1
Other aliasFLRF
HGNC (Hugo) RNF41
LocusID (NCBI) 10193
Atlas_Id 47099
Location 12q13.3  [Link to chromosome band 12q13]
Location_base_pair Starts at 56202504 and ends at 56221701 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RNF41 (12q13.2) / CS (12q13.3)RNF41 (12q13.2) / LARP4 (12q13.12)RNF41 (12q13.2) / MYO1C (17p13.3)
RNF41 (12q13.2) / PRIM1 (12q13.3)RNF41 12q13.2 / MYO1C 17p13.3RNF41 12q13.2 / PRIM1 12q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF41   18401
Cards
Entrez_Gene (NCBI)RNF41  10193  ring finger protein 41
AliasesFLRF; NRDP1; SBBI03
GeneCards (Weizmann)RNF41
Ensembl hg19 (Hinxton)ENSG00000181852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181852 [Gene_View]  chr12:56202504-56221701 [Contig_View]  RNF41 [Vega]
ICGC DataPortalENSG00000181852
TCGA cBioPortalRNF41
AceView (NCBI)RNF41
Genatlas (Paris)RNF41
WikiGenes10193
SOURCE (Princeton)RNF41
Genetics Home Reference (NIH)RNF41
Genomic and cartography
GoldenPath hg38 (UCSC)RNF41  -     chr12:56202504-56221701 -  12q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF41  -     12q13.3   [Description]    (hg19-Feb_2009)
EnsemblRNF41 - 12q13.3 [CytoView hg19]  RNF41 - 12q13.3 [CytoView hg38]
Mapping of homologs : NCBIRNF41 [Mapview hg19]  RNF41 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF077599 AK300752 AK304576 AK314811 AL080105
RefSeq transcript (Entrez)NM_001242826 NM_005785 NM_194358 NM_194359
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF41
Cluster EST : UnigeneHs.524502 [ NCBI ]
CGAP (NCI)Hs.524502
Alternative Splicing GalleryENSG00000181852
Gene ExpressionRNF41 [ NCBI-GEO ]   RNF41 [ EBI - ARRAY_EXPRESS ]   RNF41 [ SEEK ]   RNF41 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF41 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10193
GTEX Portal (Tissue expression)RNF41
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4P4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4P4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4P4
Splice isoforms : SwissVarQ9H4P4
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9H4P4
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)    ZF_SIAH (PS51081)   
Domains : Interpro (EBI)SIAH-type    TRAF-like    USP8_interacting    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS    Znf_SIAH   
Domain families : Pfam (Sanger)USP8_interact (PF08941)   
Domain families : Pfam (NCBI)pfam08941   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF41
DMDM Disease mutations10193
Blocks (Seattle)RNF41
PDB (SRS)2FZP    2GWF   
PDB (PDBSum)2FZP    2GWF   
PDB (IMB)2FZP    2GWF   
PDB (RSDB)2FZP    2GWF   
Structural Biology KnowledgeBase2FZP    2GWF   
SCOP (Structural Classification of Proteins)2FZP    2GWF   
CATH (Classification of proteins structures)2FZP    2GWF   
SuperfamilyQ9H4P4
Human Protein AtlasENSG00000181852
Peptide AtlasQ9H4P4
HPRD11520
IPIIPI00024801   IPI01014881   IPI01021772   IPI01020852   IPI01021006   IPI01021136   IPI01022479   IPI00375624   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4P4
IntAct (EBI)Q9H4P4
FunCoupENSG00000181852
BioGRIDRNF41
STRING (EMBL)RNF41
ZODIACRNF41
Ontologies - Pathways
QuickGOQ9H4P4
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  erythropoietin receptor binding  interleukin-3 receptor binding  protein binding  cytosol  autophagy  zinc ion binding  negative regulation of cell proliferation  proteasomal protein catabolic process  acid-amino acid ligase activity  Ral GTPase binding  protein domain specific binding  negative regulation of cell migration  receptor tyrosine kinase binding  protein tag  regulation of MAPK cascade  regulation of lymphocyte differentiation  regulation of myeloid cell differentiation  positive regulation of protein catabolic process  perinuclear region of cytoplasm  positive regulation of sequence-specific DNA binding transcription factor activity  protein autoubiquitination  regulation of protein kinase B signaling  ubiquitin protein ligase activity  endoplasmic reticulum tubular network  extrinsic apoptotic signaling pathway  negative regulation of macromitophagy  regulation of establishment of cell polarity  regulation of reactive oxygen species metabolic process  positive regulation of reactive oxygen species metabolic process  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  erythropoietin receptor binding  interleukin-3 receptor binding  protein binding  cytosol  autophagy  zinc ion binding  negative regulation of cell proliferation  proteasomal protein catabolic process  acid-amino acid ligase activity  Ral GTPase binding  protein domain specific binding  negative regulation of cell migration  receptor tyrosine kinase binding  protein tag  regulation of MAPK cascade  regulation of lymphocyte differentiation  regulation of myeloid cell differentiation  positive regulation of protein catabolic process  perinuclear region of cytoplasm  positive regulation of sequence-specific DNA binding transcription factor activity  protein autoubiquitination  regulation of protein kinase B signaling  ubiquitin protein ligase activity  endoplasmic reticulum tubular network  extrinsic apoptotic signaling pathway  negative regulation of macromitophagy  regulation of establishment of cell polarity  regulation of reactive oxygen species metabolic process  positive regulation of reactive oxygen species metabolic process  
Pathways : KEGGEndocytosis   
NDEx NetworkRNF41
Atlas of Cancer Signalling NetworkRNF41
Wikipedia pathwaysRNF41
Orthology - Evolution
OrthoDB10193
GeneTree (enSembl)ENSG00000181852
Phylogenetic Trees/Animal Genes : TreeFamRNF41
HOVERGENQ9H4P4
HOGENOMQ9H4P4
Homologs : HomoloGeneRNF41
Homology/Alignments : Family Browser (UCSC)RNF41
Gene fusions - Rearrangements
Fusion : MitelmanRNF41/MYO1C [12q13.2/17p13.3]  
Fusion : MitelmanRNF41/PRIM1 [12q13.2/12q13.3]  [t(12;12)(q13;q13)]  
Fusion: TCGARNF41 12q13.2 MYO1C 17p13.3 OV
Fusion: TCGARNF41 12q13.2 PRIM1 12q13.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF41 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF41
dbVarRNF41
ClinVarRNF41
1000_GenomesRNF41 
Exome Variant ServerRNF41
ExAC (Exome Aggregation Consortium)RNF41 (select the gene name)
Genetic variants : HAPMAP10193
Genomic Variants (DGV)RNF41 [DGVbeta]
DECIPHERRNF41 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF41 
Mutations
ICGC Data PortalRNF41 
TCGA Data PortalRNF41 
Broad Tumor PortalRNF41
OASIS PortalRNF41 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF41  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF41
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF41
DgiDB (Drug Gene Interaction Database)RNF41
DoCM (Curated mutations)RNF41 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF41 (select a term)
intoGenRNF41
Cancer3DRNF41(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRNF41
Genetic Testing Registry RNF41
NextProtQ9H4P4 [Medical]
TSGene10193
GENETestsRNF41
Huge Navigator RNF41 [HugePedia]
snp3D : Map Gene to Disease10193
BioCentury BCIQRNF41
ClinGenRNF41
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10193
Chemical/Pharm GKB GenePA134875033
Clinical trialRNF41
Miscellaneous
canSAR (ICR)RNF41 (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF41
EVEXRNF41
GoPubMedRNF41
iHOPRNF41
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:35:21 CEST 2017

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