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RNF43 (ring finger protein 43)

Identity

Other namesRNF124
URCC
HGNC (Hugo) RNF43
LocusID (NCBI) 54894
Location 17q22
Location_base_pair Starts at 56431038 and ends at 56494931 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RNF43   18505
Cards
Entrez_Gene (NCBI)RNF43  54894  ring finger protein 43
GeneCards (Weizmann)RNF43
Ensembl (Hinxton)ENSG00000108375 [Gene_View]  chr17:56431038-56494931 [Contig_View]  RNF43 [Vega]
ICGC DataPortalENSG00000108375
cBioPortalRNF43
AceView (NCBI)RNF43
Genatlas (Paris)RNF43
WikiGenes54894
SOURCE (Princeton)NM_017763
Genomic and cartography
GoldenPath (UCSC)RNF43  -  17q22   chr17:56431038-56494931 -  17q22   [Description]    (hg19-Feb_2009)
EnsemblRNF43 - 17q22 [CytoView]
Mapping of homologs : NCBIRNF43 [Mapview]
OMIM612482   
Gene and transcription
Genbank (Entrez)AB081837 AK000322 AK291027 AK296769 AK298789
RefSeq transcript (Entrez)NM_017763
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838448 NW_004929407
Consensus coding sequences : CCDS (NCBI)RNF43
Cluster EST : UnigeneHs.584916 [ NCBI ]
CGAP (NCI)Hs.584916
Alternative Splicing : Fast-db (Paris)GSHG0013604
Alternative Splicing GalleryENSG00000108375
Gene ExpressionRNF43 [ NCBI-GEO ]     RNF43 [ SEEK ]   RNF43 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68DV7 (Uniprot)
NextProtQ68DV7  [Medical]
With graphics : InterProQ68DV7
Splice isoforms : SwissVarQ68DV7 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING [organisation]   Znf_RING/FYVE/PHD [organisation]  
Related proteins : CluSTrQ68DV7
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
DMDM Disease mutations54894
Blocks (Seattle)Q68DV7
PDB (SRS)4KNG   
PDB (PDBSum)4KNG   
PDB (IMB)4KNG   
PDB (RSDB)4KNG   
Human Protein AtlasENSG00000108375 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ68DV7
HPRD07896
IPIIPI00744070   IPI00930434   IPI00930238   IPI00930185   
Protein Interaction databases
DIP (DOE-UCLA)Q68DV7
IntAct (EBI)Q68DV7
FunCoupENSG00000108375
BioGRIDRNF43
InParanoidQ68DV7
Interologous Interaction database Q68DV7
IntegromeDBRNF43
STRING (EMBL)RNF43
Ontologies - Pathways
Ontology : AmiGOubiquitin-protein transferase activity  frizzled binding  protein binding  nuclear envelope  endoplasmic reticulum membrane  integral component of plasma membrane  zinc ion binding  Wnt signaling pathway  protein ubiquitination  ligase activity  negative regulation of Wnt signaling pathway  Wnt receptor catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  stem cell proliferation  
Ontology : EGO-EBIubiquitin-protein transferase activity  frizzled binding  protein binding  nuclear envelope  endoplasmic reticulum membrane  integral component of plasma membrane  zinc ion binding  Wnt signaling pathway  protein ubiquitination  ligase activity  negative regulation of Wnt signaling pathway  Wnt receptor catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  stem cell proliferation  
Protein Interaction DatabaseRNF43
Wikipedia pathwaysRNF43
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RNF43
snp3D : Map Gene to Disease54894
SNP (GeneSNP Utah)RNF43
SNP : HGBaseRNF43
Genetic variants : HAPMAPRNF43
Exome VariantRNF43
1000_GenomesRNF43 
ICGC programENSG00000108375 
Cancer Gene: CensusRNF43 
Somatic Mutations in Cancer : COSMICRNF43 
CONAN: Copy Number AnalysisRNF43 
Mutations and Diseases : HGMDRNF43
Genomic VariantsRNF43  RNF43 [DGVbeta]
dbVarRNF43
ClinVarRNF43
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM612482   
MedgenRNF43
GENETestsRNF43
Disease Genetic AssociationRNF43
Huge Navigator RNF43 [HugePedia]  RNF43 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneRNF43
Homology/Alignments : Family Browser (UCSC)RNF43
Phylogenetic Trees/Animal Genes : TreeFamRNF43
Chemical/Protein Interactions : CTD54894
Chemical/Pharm GKB GenePA34441
Clinical trialRNF43
Cancer Resource (Charite)ENSG00000108375
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineRNF43
iHOPRNF43
OncoSearchRNF43
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:46:14 CEST 2014

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