RNF6 (ring finger protein 6)

2003-02-01  

Identity

HGNC
LOCATION
13q12.13
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 6049
MIM: 604242
HGNC: 10069
Ensembl: ENSG00000127870

Variants:

dbSNP: 6049
ClinVar: 6049
TCGA: ENSG00000127870
COSMIC: RNF6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127870ENST00000346166Q9Y252
ENSG00000127870ENST00000346166A0A024RDP2
ENSG00000127870ENST00000381570Q9Y252
ENSG00000127870ENST00000381570A0A024RDP2
ENSG00000127870ENST00000381588Q9Y252
ENSG00000127870ENST00000381588A0A024RDP2

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380723022024Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.0
380723022024Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.0
352786112022Ring finger protein 6 enhances chemo-resistance by transcriptionally activating proliferating cell nuclear antigen expression and attenuating DNA damage in lung adenocarcinoma.5
353695712022RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.1
359736382022E3 ubiquitin ligase RNF6 promotes antiviral immune responses through enhancing the expression of interferon stimulated genes in myeloid cells.2
352786112022Ring finger protein 6 enhances chemo-resistance by transcriptionally activating proliferating cell nuclear antigen expression and attenuating DNA damage in lung adenocarcinoma.5
353695712022RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.1
359736382022E3 ubiquitin ligase RNF6 promotes antiviral immune responses through enhancing the expression of interferon stimulated genes in myeloid cells.2
334858422021Gene commander in the trash heap: Transcriptional regulation and ubiquitination modification mediated by RNF6 in carcinogenesis.4
340818372021Knockdown of RNF6 inhibits HeLa cervical cancer cell growth via suppression of MAPK/ERK signaling.4
343524412021RNF6 promotes colorectal cancer invasion and migration via the Wnt/β-catenin pathway by inhibiting GSK3β activity.7
346113112021RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2.3
334858422021Gene commander in the trash heap: Transcriptional regulation and ubiquitination modification mediated by RNF6 in carcinogenesis.4
340818372021Knockdown of RNF6 inhibits HeLa cervical cancer cell growth via suppression of MAPK/ERK signaling.4
343524412021RNF6 promotes colorectal cancer invasion and migration via the Wnt/β-catenin pathway by inhibiting GSK3β activity.7

Citation

Dessen P

RNF6 (ring finger protein 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42139/rnf6