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RNF6 (ring finger protein 6)

Identity

Alias_namesring finger protein (C3H2C3 type) 6
Alias_symbol (synonym)DKFZp686P0776
Other alias-
HGNC (Hugo) RNF6
LocusID (NCBI) 6049
Atlas_Id 42139
Location 13q12.13  [Link to chromosome band 13q12]
Location_base_pair Starts at 26212768 and ends at 26222371 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RNF6 (13q12.13) / RNF6 (13q12.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RNF6   10069
Cards
Entrez_Gene (NCBI)RNF6  6049  ring finger protein 6
Aliases
GeneCards (Weizmann)RNF6
Ensembl hg19 (Hinxton)ENSG00000127870 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127870 [Gene_View]  chr13:26212768-26222371 [Contig_View]  RNF6 [Vega]
ICGC DataPortalENSG00000127870
TCGA cBioPortalRNF6
AceView (NCBI)RNF6
Genatlas (Paris)RNF6
WikiGenes6049
SOURCE (Princeton)RNF6
Genetics Home Reference (NIH)RNF6
Genomic and cartography
GoldenPath hg38 (UCSC)RNF6  -     chr13:26212768-26222371 -  13q12.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RNF6  -     13q12.13   [Description]    (hg19-Feb_2009)
EnsemblRNF6 - 13q12.13 [CytoView hg19]  RNF6 - 13q12.13 [CytoView hg38]
Mapping of homologs : NCBIRNF6 [Mapview hg19]  RNF6 [Mapview hg38]
OMIM133239   604242   
Gene and transcription
Genbank (Entrez)AF293342 AJ010346 AJ010347 AK293272 AK312435
RefSeq transcript (Entrez)NM_005977 NM_183043 NM_183044 NM_183045
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RNF6
Cluster EST : UnigeneHs.136885 [ NCBI ]
CGAP (NCI)Hs.136885
Alternative Splicing GalleryENSG00000127870
Gene ExpressionRNF6 [ NCBI-GEO ]   RNF6 [ EBI - ARRAY_EXPRESS ]   RNF6 [ SEEK ]   RNF6 [ MEM ]
Gene Expression Viewer (FireBrowse)RNF6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6049
GTEX Portal (Tissue expression)RNF6
Human Protein AtlasENSG00000127870-RNF6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y252   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y252  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y252
Splice isoforms : SwissVarQ9Y252
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9Y252
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)RNF6
DMDM Disease mutations6049
Blocks (Seattle)RNF6
SuperfamilyQ9Y252
Human Protein Atlas [tissue]ENSG00000127870-RNF6 [tissue]
Peptide AtlasQ9Y252
HPRD05027
IPIIPI00031752   IPI01012568   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y252
IntAct (EBI)Q9Y252
FunCoupENSG00000127870
BioGRIDRNF6
STRING (EMBL)RNF6
ZODIACRNF6
Ontologies - Pathways
QuickGOQ9Y252
Ontology : AmiGODNA binding  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  ubiquitin-dependent protein catabolic process  zinc ion binding  PML body  axon  negative regulation of axon extension  nuclear membrane  proteasome-mediated ubiquitin-dependent protein catabolic process  intracellular membrane-bounded organelle  protein K27-linked ubiquitination  positive regulation of transcription, DNA-templated  androgen receptor binding  regulation of androgen receptor signaling pathway  ubiquitin protein ligase activity  protein K48-linked ubiquitination  protein K6-linked ubiquitination  
Ontology : EGO-EBIDNA binding  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  ubiquitin-dependent protein catabolic process  zinc ion binding  PML body  axon  negative regulation of axon extension  nuclear membrane  proteasome-mediated ubiquitin-dependent protein catabolic process  intracellular membrane-bounded organelle  protein K27-linked ubiquitination  positive regulation of transcription, DNA-templated  androgen receptor binding  regulation of androgen receptor signaling pathway  ubiquitin protein ligase activity  protein K48-linked ubiquitination  protein K6-linked ubiquitination  
NDEx NetworkRNF6
Atlas of Cancer Signalling NetworkRNF6
Wikipedia pathwaysRNF6
Orthology - Evolution
OrthoDB6049
GeneTree (enSembl)ENSG00000127870
Phylogenetic Trees/Animal Genes : TreeFamRNF6
HOVERGENQ9Y252
HOGENOMQ9Y252
Homologs : HomoloGeneRNF6
Homology/Alignments : Family Browser (UCSC)RNF6
Gene fusions - Rearrangements
Tumor Fusion PortalRNF6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRNF6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RNF6
dbVarRNF6
ClinVarRNF6
1000_GenomesRNF6 
Exome Variant ServerRNF6
ExAC (Exome Aggregation Consortium)ENSG00000127870
GNOMAD BrowserENSG00000127870
Genetic variants : HAPMAP6049
Genomic Variants (DGV)RNF6 [DGVbeta]
DECIPHERRNF6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRNF6 
Mutations
ICGC Data PortalRNF6 
TCGA Data PortalRNF6 
Broad Tumor PortalRNF6
OASIS PortalRNF6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRNF6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRNF6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RNF6
DgiDB (Drug Gene Interaction Database)RNF6
DoCM (Curated mutations)RNF6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RNF6 (select a term)
intoGenRNF6
Cancer3DRNF6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM133239    604242   
Orphanet
DisGeNETRNF6
MedgenRNF6
Genetic Testing Registry RNF6
NextProtQ9Y252 [Medical]
TSGene6049
GENETestsRNF6
Target ValidationRNF6
Huge Navigator RNF6 [HugePedia]
snp3D : Map Gene to Disease6049
BioCentury BCIQRNF6
ClinGenRNF6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6049
Chemical/Pharm GKB GenePA34443
Clinical trialRNF6
Miscellaneous
canSAR (ICR)RNF6 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRNF6
EVEXRNF6
GoPubMedRNF6
iHOPRNF6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:32:46 CET 2017

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