RNH1 (ribonuclease/angiogenin inhibitor 1)

2007-02-01  

Identity

HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
RAI,RNH
FUSION GENES

Other Information

Locus ID:

NCBI: 6050
MIM: 173320
HGNC: 10074
Ensembl: ENSG00000023191

Variants:

dbSNP: 6050
ClinVar: 6050
TCGA: ENSG00000023191
COSMIC: RNH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000023191ENST00000354420P13489
ENSG00000023191ENST00000354420A0A140VJT8
ENSG00000023191ENST00000356187P13489
ENSG00000023191ENST00000356187A0A140VJT8
ENSG00000023191ENST00000397604P13489
ENSG00000023191ENST00000397604A0A140VJT8
ENSG00000023191ENST00000397614P13489
ENSG00000023191ENST00000397614A0A140VJT8
ENSG00000023191ENST00000397615P13489
ENSG00000023191ENST00000397615A0A140VJT8
ENSG00000023191ENST00000438658P13489
ENSG00000023191ENST00000438658A0A140VJT8
ENSG00000023191ENST00000524464E9PMA9
ENSG00000023191ENST00000525701E9PR82
ENSG00000023191ENST00000527485E9PIM9
ENSG00000023191ENST00000529115E9PMN0
ENSG00000023191ENST00000529306E9PMJ3
ENSG00000023191ENST00000529368E9PLZ3
ENSG00000023191ENST00000529768H0YCR7
ENSG00000023191ENST00000531149E9PIK5
ENSG00000023191ENST00000531540A0A0J9YXC4
ENSG00000023191ENST00000532055E9PMI1
ENSG00000023191ENST00000533410P13489
ENSG00000023191ENST00000533410A0A140VJT8
ENSG00000023191ENST00000534797P13489
ENSG00000023191ENST00000534797A0A140VJT8

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
173506502007Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.57
190343802009Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.36
203810702010Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia.22
241078472014An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract.18
221627622011PTEN modulates miR-21 processing via RNA-regulatory protein RNH1.15
251931132014Angiogenin interacts with ribonuclease inhibitor regulating PI3K/AKT/mTOR signaling pathway in bladder cancer cells.15
159365902005Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50.12
235844802014RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells.12
212764512011The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei.11
247691292014Ribonuclease inhibitor up-regulation inhibits the growth and induces apoptosis in murine melanoma cells through repression of angiogenin and ILK/PI3K/AKT signaling pathway.11

Citation

Dessen P

RNH1 (ribonuclease/angiogenin inhibitor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45618/rnh1