RNLS (renalase, FAD dependent amine oxidase)

2014-08-01  

Identity

HGNC
LOCATION
10q23.31
LOCUSID
ALIAS
C10orf59,RENALASE
FUSION GENES

Other Information

Locus ID:

NCBI: 55328
MIM: 609360
HGNC: 25641
Ensembl: ENSG00000184719

Variants:

dbSNP: 55328
ClinVar: 55328
TCGA: ENSG00000184719
COSMIC: RNLS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184719ENST00000331772Q5VYX0
ENSG00000184719ENST00000371947Q5VYX0
ENSG00000184719ENST00000437752F6XA08

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

References

Pubmed IDYearTitleCitations
158412072005Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.87
158412072005Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.87
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
178461262007Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.68
172162032007Renalase gene is a novel susceptibility gene for essential hypertension: a two-stage association study in northern Han Chinese population.29
172162032007Renalase gene is a novel susceptibility gene for essential hypertension: a two-stage association study in northern Han Chinese population.29
209759952010A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.25
245111382014Renalase prevents AKI independent of amine oxidase activity.22
228912152012Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.20
219645802011Renalase gene polymorphisms in patients with type 2 diabetes, hypertension and stroke.19

Citation

Dessen P

RNLS (renalase, FAD dependent amine oxidase)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54588/rnls