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ROBO4 (roundabout guidance receptor 4)

Identity

Alias_namesroundabout homolog 4 (Drosophila)
roundabout, axon guidance receptor, homolog 4 (Drosophila)
Alias_symbol (synonym)FLJ20798
MRB
ECSM4
Other alias
HGNC (Hugo) ROBO4
LocusID (NCBI) 54538
Atlas_Id 45897
Location 11q24.2  [Link to chromosome band 11q24]
Location_base_pair Starts at 124754114 and ends at 124767831 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ROBO4   17985
Cards
Entrez_Gene (NCBI)ROBO4  54538  roundabout guidance receptor 4
AliasesECSM4; MRB
GeneCards (Weizmann)ROBO4
Ensembl hg19 (Hinxton)ENSG00000154133 [Gene_View]  chr11:124754114-124767831 [Contig_View]  ROBO4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000154133 [Gene_View]  chr11:124754114-124767831 [Contig_View]  ROBO4 [Vega]
ICGC DataPortalENSG00000154133
TCGA cBioPortalROBO4
AceView (NCBI)ROBO4
Genatlas (Paris)ROBO4
WikiGenes54538
SOURCE (Princeton)ROBO4
Genetics Home Reference (NIH)ROBO4
Genomic and cartography
GoldenPath hg19 (UCSC)ROBO4  -     chr11:124754114-124767831 -  11q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ROBO4  -     11q24.2   [Description]    (hg38-Dec_2013)
EnsemblROBO4 - 11q24.2 [CytoView hg19]  ROBO4 - 11q24.2 [CytoView hg38]
Mapping of homologs : NCBIROBO4 [Mapview hg19]  ROBO4 [Mapview hg38]
OMIM607528   
Gene and transcription
Genbank (Entrez)AF361473 AK000805 AK025195 AK027852 AK074163
RefSeq transcript (Entrez)NM_001301088 NM_019055
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)ROBO4
Cluster EST : UnigeneHs.524121 [ NCBI ]
CGAP (NCI)Hs.524121
Alternative Splicing GalleryENSG00000154133
Gene ExpressionROBO4 [ NCBI-GEO ]   ROBO4 [ EBI - ARRAY_EXPRESS ]   ROBO4 [ SEEK ]   ROBO4 [ MEM ]
Gene Expression Viewer (FireBrowse)ROBO4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54538
GTEX Portal (Tissue expression)ROBO4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WZ75   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WZ75  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WZ75
Splice isoforms : SwissVarQ8WZ75
PhosPhoSitePlusQ8WZ75
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam00041    pfam07679   
Domain families : Smart (EMBL)FN3 (SM00060)  IGc2 (SM00408)  
Conserved Domain (NCBI)ROBO4
DMDM Disease mutations54538
Blocks (Seattle)ROBO4
SuperfamilyQ8WZ75
Human Protein AtlasENSG00000154133
Peptide AtlasQ8WZ75
HPRD09604
IPIIPI00103871   IPI00418144   IPI00418145   IPI01025285   
Protein Interaction databases
DIP (DOE-UCLA)Q8WZ75
IntAct (EBI)Q8WZ75
FunCoupENSG00000154133
BioGRIDROBO4
STRING (EMBL)ROBO4
ZODIACROBO4
Ontologies - Pathways
QuickGOQ8WZ75
Ontology : AmiGOangiogenesis  receptor activity  integral component of membrane  cell differentiation  regulation of cell migration  regulation of apoptotic process  extracellular exosome  
Ontology : EGO-EBIangiogenesis  receptor activity  integral component of membrane  cell differentiation  regulation of cell migration  regulation of apoptotic process  extracellular exosome  
NDEx NetworkROBO4
Atlas of Cancer Signalling NetworkROBO4
Wikipedia pathwaysROBO4
Orthology - Evolution
OrthoDB54538
GeneTree (enSembl)ENSG00000154133
Phylogenetic Trees/Animal Genes : TreeFamROBO4
HOVERGENQ8WZ75
HOGENOMQ8WZ75
Homologs : HomoloGeneROBO4
Homology/Alignments : Family Browser (UCSC)ROBO4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerROBO4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ROBO4
dbVarROBO4
ClinVarROBO4
1000_GenomesROBO4 
Exome Variant ServerROBO4
ExAC (Exome Aggregation Consortium)ROBO4 (select the gene name)
Genetic variants : HAPMAP54538
Genomic Variants (DGV)ROBO4 [DGVbeta]
DECIPHER (Syndromes)11:124754114-124767831  ENSG00000154133
CONAN: Copy Number AnalysisROBO4 
Mutations
ICGC Data PortalROBO4 
TCGA Data PortalROBO4 
Broad Tumor PortalROBO4
OASIS PortalROBO4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICROBO4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDROBO4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ROBO4
DgiDB (Drug Gene Interaction Database)ROBO4
DoCM (Curated mutations)ROBO4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ROBO4 (select a term)
intoGenROBO4
Cancer3DROBO4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607528   
Orphanet
MedgenROBO4
Genetic Testing Registry ROBO4
NextProtQ8WZ75 [Medical]
TSGene54538
GENETestsROBO4
Huge Navigator ROBO4 [HugePedia]
snp3D : Map Gene to Disease54538
BioCentury BCIQROBO4
ClinGenROBO4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54538
Chemical/Pharm GKB GenePA34622
Clinical trialROBO4
Miscellaneous
canSAR (ICR)ROBO4 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineROBO4
EVEXROBO4
GoPubMedROBO4
iHOPROBO4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:25:29 CET 2017

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