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RORC (RAR related orphan receptor C)

Identity

Alias_namesRAR-related orphan receptor C
Alias_symbol (synonym)RZRG
RORG
NR1F3
TOR
Other aliasIMD42
RZR-GAMMA
HGNC (Hugo) RORC
LocusID (NCBI) 6097
Atlas_Id 47292
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151778547 and ends at 151798553 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
VPS72 (1q21.3) / RORC (1q21.3)VPS72 1q21.3 / RORC 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RORC   10260
Cards
Entrez_Gene (NCBI)RORC  6097  RAR related orphan receptor C
AliasesIMD42; NR1F3; RORG; RZR-GAMMA; 
RZRG; TOR
GeneCards (Weizmann)RORC
Ensembl hg19 (Hinxton)ENSG00000143365 [Gene_View]  chr1:151778547-151798553 [Contig_View]  RORC [Vega]
Ensembl hg38 (Hinxton)ENSG00000143365 [Gene_View]  chr1:151778547-151798553 [Contig_View]  RORC [Vega]
ICGC DataPortalENSG00000143365
TCGA cBioPortalRORC
AceView (NCBI)RORC
Genatlas (Paris)RORC
WikiGenes6097
SOURCE (Princeton)RORC
Genetics Home Reference (NIH)RORC
Genomic and cartography
GoldenPath hg19 (UCSC)RORC  -     chr1:151778547-151798553 -  1q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RORC  -     1q21.3   [Description]    (hg38-Dec_2013)
EnsemblRORC - 1q21.3 [CytoView hg19]  RORC - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIRORC [Mapview hg19]  RORC [Mapview hg38]
OMIM602943   616622   
Gene and transcription
Genbank (Entrez)AB307696 AF075096 AK097994 AK128522 AK223137
RefSeq transcript (Entrez)NM_001001523 NM_005060
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_029118 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)RORC
Cluster EST : UnigeneHs.607993 [ NCBI ]
CGAP (NCI)Hs.607993
Alternative Splicing GalleryENSG00000143365
Gene ExpressionRORC [ NCBI-GEO ]   RORC [ EBI - ARRAY_EXPRESS ]   RORC [ SEEK ]   RORC [ MEM ]
Gene Expression Viewer (FireBrowse)RORC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6097
GTEX Portal (Tissue expression)RORC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51449   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51449  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51449
Splice isoforms : SwissVarP51449
PhosPhoSitePlusP51449
Domaine pattern : Prosite (Expaxy)NUCLEAR_REC_DBD_1 (PS00031)    NUCLEAR_REC_DBD_2 (PS51030)   
Domains : Interpro (EBI)Nucl_hrmn_rcpt_lig-bd    Nuclear_hrmn_rcpt    ROR_rcpt    Znf_hrmn_rcpt    Znf_NHR/GATA   
Domain families : Pfam (Sanger)Hormone_recep (PF00104)    zf-C4 (PF00105)   
Domain families : Pfam (NCBI)pfam00104    pfam00105   
Domain families : Smart (EMBL)HOLI (SM00430)  ZnF_C4 (SM00399)  
Conserved Domain (NCBI)RORC
DMDM Disease mutations6097
Blocks (Seattle)RORC
PDB (SRS)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
PDB (PDBSum)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
PDB (IMB)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
PDB (RSDB)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
Structural Biology KnowledgeBase3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
SCOP (Structural Classification of Proteins)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
CATH (Classification of proteins structures)3B0W    3KYT    3L0J    3L0L    4NB6    4NIE    4QM0    4S14    4WLB    4WPF    4WQP    4XT9    4YMQ    4YPQ    4ZJR    4ZJW    4ZOM    5APH    5APJ    5APK    5C4O    5C4S    5C4T    5C4U   
SuperfamilyP51449
Human Protein AtlasENSG00000143365
Peptide AtlasP51449
HPRD04250
IPIIPI00216710   IPI00418178   IPI00909441   IPI00955841   
Protein Interaction databases
DIP (DOE-UCLA)P51449
IntAct (EBI)P51449
FunCoupENSG00000143365
BioGRIDRORC
STRING (EMBL)RORC
ZODIACRORC
Ontologies - Pathways
QuickGOP51449
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  steroid hormone receptor activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleolus  transcription initiation from RNA polymerase II promoter  xenobiotic metabolic process  oxysterol binding  zinc ion binding  regulation of glucose metabolic process  regulation of steroid metabolic process  intracellular receptor signaling pathway  intracellular receptor signaling pathway  circadian regulation of gene expression  cellular response to sterol  T-helper cell differentiation  positive regulation of circadian rhythm  intracellular membrane-bounded organelle  steroid hormone mediated signaling pathway  sequence-specific DNA binding  sequence-specific DNA binding  regulation of fat cell differentiation  positive regulation of transcription, DNA-templated  lymph node development  Peyer's patch development  adipose tissue development  regulation of transcription involved in cell fate commitment  negative regulation of thymocyte apoptotic process  T-helper 17 cell differentiation  transcription factor activity, direct ligand regulated sequence-specific DNA binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  steroid hormone receptor activity  RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleolus  transcription initiation from RNA polymerase II promoter  xenobiotic metabolic process  oxysterol binding  zinc ion binding  regulation of glucose metabolic process  regulation of steroid metabolic process  intracellular receptor signaling pathway  intracellular receptor signaling pathway  circadian regulation of gene expression  cellular response to sterol  T-helper cell differentiation  positive regulation of circadian rhythm  intracellular membrane-bounded organelle  steroid hormone mediated signaling pathway  sequence-specific DNA binding  sequence-specific DNA binding  regulation of fat cell differentiation  positive regulation of transcription, DNA-templated  lymph node development  Peyer's patch development  adipose tissue development  regulation of transcription involved in cell fate commitment  negative regulation of thymocyte apoptotic process  T-helper 17 cell differentiation  transcription factor activity, direct ligand regulated sequence-specific DNA binding  
Pathways : KEGGCircadian rhythm    Inflammatory bowel disease (IBD)   
NDEx NetworkRORC
Atlas of Cancer Signalling NetworkRORC
Wikipedia pathwaysRORC
Orthology - Evolution
OrthoDB6097
GeneTree (enSembl)ENSG00000143365
Phylogenetic Trees/Animal Genes : TreeFamRORC
HOVERGENP51449
HOGENOMP51449
Homologs : HomoloGeneRORC
Homology/Alignments : Family Browser (UCSC)RORC
Gene fusions - Rearrangements
Fusion : MitelmanVPS72/RORC [1q21.3/1q21.3]  [t(1;1)(q21;q21)]  
Fusion: TCGAVPS72 1q21.3 RORC 1q21.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRORC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RORC
dbVarRORC
ClinVarRORC
1000_GenomesRORC 
Exome Variant ServerRORC
ExAC (Exome Aggregation Consortium)RORC (select the gene name)
Genetic variants : HAPMAP6097
Genomic Variants (DGV)RORC [DGVbeta]
DECIPHER (Syndromes)1:151778547-151798553  ENSG00000143365
CONAN: Copy Number AnalysisRORC 
Mutations
ICGC Data PortalRORC 
TCGA Data PortalRORC 
Broad Tumor PortalRORC
OASIS PortalRORC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRORC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRORC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RORC
DgiDB (Drug Gene Interaction Database)RORC
DoCM (Curated mutations)RORC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RORC (select a term)
intoGenRORC
Cancer3DRORC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602943    616622   
Orphanet
MedgenRORC
Genetic Testing Registry RORC
NextProtP51449 [Medical]
TSGene6097
GENETestsRORC
Huge Navigator RORC [HugePedia]
snp3D : Map Gene to Disease6097
BioCentury BCIQRORC
ClinGenRORC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6097
Chemical/Pharm GKB GenePA34632
Clinical trialRORC
Miscellaneous
canSAR (ICR)RORC (select the gene name)
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRORC
EVEXRORC
GoPubMedRORC
iHOPRORC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:25:31 CET 2017

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