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RPA4 (replication protein A4)

Identity

Alias_namesreplication protein A4, 34kDa
replication protein A4, 30kDa
Alias_symbol (synonym)HSU24186
Other alias
HGNC (Hugo) RPA4
LocusID (NCBI) 29935
Atlas_Id 43989
Location Xq21.33  [Link to chromosome band Xq21]
Location_base_pair Starts at 96883908 and ends at 96885451 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

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Nomenclature
HGNC (Hugo)RPA4   30305
Cards
Entrez_Gene (NCBI)RPA4  29935  replication protein A4
AliasesHSU24186
GeneCards (Weizmann)RPA4
Ensembl hg19 (Hinxton)ENSG00000204086 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204086 [Gene_View]  chrX:96883908-96885451 [Contig_View]  RPA4 [Vega]
ICGC DataPortalENSG00000204086
TCGA cBioPortalRPA4
AceView (NCBI)RPA4
Genatlas (Paris)RPA4
WikiGenes29935
SOURCE (Princeton)RPA4
Genetics Home Reference (NIH)RPA4
Genomic and cartography
GoldenPath hg38 (UCSC)RPA4  -     chrX:96883908-96885451 +  Xq21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPA4  -     Xq21.33   [Description]    (hg19-Feb_2009)
EnsemblRPA4 - Xq21.33 [CytoView hg19]  RPA4 - Xq21.33 [CytoView hg38]
Mapping of homologs : NCBIRPA4 [Mapview hg19]  RPA4 [Mapview hg38]
OMIM300767   
Gene and transcription
Genbank (Entrez)BC069791 BC069808 BC069824 BC104013 BC104014
RefSeq transcript (Entrez)NM_013347
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPA4
Cluster EST : UnigeneHs.659349 [ NCBI ]
CGAP (NCI)Hs.659349
Alternative Splicing GalleryENSG00000204086
Gene ExpressionRPA4 [ NCBI-GEO ]   RPA4 [ EBI - ARRAY_EXPRESS ]   RPA4 [ SEEK ]   RPA4 [ MEM ]
Gene Expression Viewer (FireBrowse)RPA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29935
GTEX Portal (Tissue expression)RPA4
Human Protein AtlasENSG00000204086-RPA4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13156   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13156  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13156
Splice isoforms : SwissVarQ13156
PhosPhoSitePlusQ13156
Domains : Interpro (EBI)NA-bd_OB-fold    Rfa2/RPA32    RPA_C    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)RPA_C (PF08784)   
Domain families : Pfam (NCBI)pfam08784   
Conserved Domain (NCBI)RPA4
DMDM Disease mutations29935
Blocks (Seattle)RPA4
SuperfamilyQ13156
Human Protein Atlas [tissue]ENSG00000204086-RPA4 [tissue]
Peptide AtlasQ13156
HPRD06591
IPIIPI00011917   
Protein Interaction databases
DIP (DOE-UCLA)Q13156
IntAct (EBI)Q13156
FunCoupENSG00000204086
BioGRIDRPA4
STRING (EMBL)RPA4
ZODIACRPA4
Ontologies - Pathways
QuickGOQ13156
Ontology : AmiGODNA damage checkpoint  G1/S transition of mitotic cell cycle  single-stranded DNA binding  nucleus  nucleoplasm  DNA replication factor A complex  DNA replication initiation  nucleotide-excision repair  DNA recombination  nuclear DNA replication  
Ontology : EGO-EBIDNA damage checkpoint  G1/S transition of mitotic cell cycle  single-stranded DNA binding  nucleus  nucleoplasm  DNA replication factor A complex  DNA replication initiation  nucleotide-excision repair  DNA recombination  nuclear DNA replication  
Pathways : KEGGDNA replication    Nucleotide excision repair    Mismatch repair    Homologous recombination    Fanconi anemia pathway   
NDEx NetworkRPA4
Atlas of Cancer Signalling NetworkRPA4
Wikipedia pathwaysRPA4
Orthology - Evolution
OrthoDB29935
GeneTree (enSembl)ENSG00000204086
Phylogenetic Trees/Animal Genes : TreeFamRPA4
HOVERGENQ13156
HOGENOMQ13156
Homologs : HomoloGeneRPA4
Homology/Alignments : Family Browser (UCSC)RPA4
Gene fusions - Rearrangements
Tumor Fusion PortalRPA4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPA4
dbVarRPA4
ClinVarRPA4
1000_GenomesRPA4 
Exome Variant ServerRPA4
ExAC (Exome Aggregation Consortium)ENSG00000204086
GNOMAD BrowserENSG00000204086
Genetic variants : HAPMAP29935
Genomic Variants (DGV)RPA4 [DGVbeta]
DECIPHERRPA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPA4 
Mutations
ICGC Data PortalRPA4 
TCGA Data PortalRPA4 
Broad Tumor PortalRPA4
OASIS PortalRPA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch RPA4
DgiDB (Drug Gene Interaction Database)RPA4
DoCM (Curated mutations)RPA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPA4 (select a term)
intoGenRPA4
Cancer3DRPA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300767   
Orphanet
DisGeNETRPA4
MedgenRPA4
Genetic Testing Registry RPA4
NextProtQ13156 [Medical]
TSGene29935
GENETestsRPA4
Target ValidationRPA4
Huge Navigator RPA4 [HugePedia]
snp3D : Map Gene to Disease29935
BioCentury BCIQRPA4
ClinGenRPA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29935
Chemical/Pharm GKB GenePA134988548
Clinical trialRPA4
Miscellaneous
canSAR (ICR)RPA4 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPA4
EVEXRPA4
GoPubMedRPA4
iHOPRPA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:32:51 CET 2017

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