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RPL11 (ribosomal protein L11)

Identity

Other namesDBA7
GIG34
L11
HGNC (Hugo) RPL11
LocusID (NCBI) 6135
Atlas_Id 46411
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 24018269 and ends at 24022915 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADAMTS2 (5q35.3) / RPL11 (1p36.11)FRYL (4p11) / RPL11 (1p36.11)MIR6723 (1p36.33) / RPL11 (1p36.11)
MTATP6P1 () / RPL11 (1p36.11)NAA50 (3q13.2) / RPL11 (1p36.11)RP5-857K21.11 () / RPL11 (1p36.11)
RP5-857K21.7 () / RPL11 (1p36.11)RPL11 (1p36.11) / EPHX1 (1q42.12)RPL11 (1p36.11) / KDM5C (Xp11.22)
RPL11 (1p36.11) / MYH9 (22q12.3)RPL11 (1p36.11) / NDUFB4 (3q13.33)RPL11 (1p36.11) / RPL11 (1p36.11)
RPL11 (1p36.11) / STRN4 (19q13.32)RPL11 (1p36.11) / TCEB3 (1p36.11)RPL11 (1p36.11) / TKT (3p21.1)
RPL11 (1p36.11) / TMCO6 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Diamond-Blackfan anemia (DBA)

External links

Nomenclature
HGNC (Hugo)RPL11   10301
Cards
Entrez_Gene (NCBI)RPL11  6135  ribosomal protein L11
AliasesDBA7; GIG34; L11
GeneCards (Weizmann)RPL11
Ensembl hg19 (Hinxton)ENSG00000142676 [Gene_View]  chr1:24018269-24022915 [Contig_View]  RPL11 [Vega]
Ensembl hg38 (Hinxton)ENSG00000142676 [Gene_View]  chr1:24018269-24022915 [Contig_View]  RPL11 [Vega]
ICGC DataPortalENSG00000142676
TCGA cBioPortalRPL11
AceView (NCBI)RPL11
Genatlas (Paris)RPL11
WikiGenes6135
SOURCE (Princeton)RPL11
Genomic and cartography
GoldenPath hg19 (UCSC)RPL11  -     chr1:24018269-24022915 +  1p36.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RPL11  -     1p36.11   [Description]    (hg38-Dec_2013)
EnsemblRPL11 - 1p36.11 [CytoView hg19]  RPL11 - 1p36.11 [CytoView hg38]
Mapping of homologs : NCBIRPL11 [Mapview hg19]  RPL11 [Mapview hg38]
OMIM604175   612562   
Gene and transcription
Genbank (Entrez)AF432212 AK311816 AY871274 BC018970 BF240826
RefSeq transcript (Entrez)NM_000975 NM_001199802
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_011741 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)RPL11
Cluster EST : UnigeneHs.719951 [ NCBI ]
CGAP (NCI)Hs.719951
Alternative Splicing GalleryENSG00000142676
Gene ExpressionRPL11 [ NCBI-GEO ]   RPL11 [ EBI - ARRAY_EXPRESS ]   RPL11 [ SEEK ]   RPL11 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6135
GTEX Portal (Tissue expression)RPL11
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62913 (Uniprot)
NextProtP62913  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62913
Splice isoforms : SwissVarP62913 (Swissvar)
PhosPhoSitePlusP62913
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L5 (PS00358)   
Domains : Interpro (EBI)Ribosomal_L5    Ribosomal_L5_C    Ribosomal_L5_CS    Ribosomal_L5_domain    Ribosomal_L5_N   
Domain families : Pfam (Sanger)Ribosomal_L5 (PF00281)    Ribosomal_L5_C (PF00673)   
Domain families : Pfam (NCBI)pfam00281    pfam00673   
DMDM Disease mutations6135
Blocks (Seattle)RPL11
PDB (SRS)4UG0    4V6X    4XXB    5AJ0   
PDB (PDBSum)4UG0    4V6X    4XXB    5AJ0   
PDB (IMB)4UG0    4V6X    4XXB    5AJ0   
PDB (RSDB)4UG0    4V6X    4XXB    5AJ0   
Structural Biology KnowledgeBase4UG0    4V6X    4XXB    5AJ0   
SCOP (Structural Classification of Proteins)4UG0    4V6X    4XXB    5AJ0   
CATH (Classification of proteins structures)4UG0    4V6X    4XXB    5AJ0   
SuperfamilyP62913
Human Protein AtlasENSG00000142676
Peptide AtlasP62913
HPRD10364
IPIIPI00376798   IPI00746438   IPI00647674   IPI00647168   
Protein Interaction databases
DIP (DOE-UCLA)P62913
IntAct (EBI)P62913
FunCoupENSG00000142676
BioGRIDRPL11
STRING (EMBL)RPL11
ZODIACRPL11
Ontologies - Pathways
QuickGOP62913
Ontology : AmiGOribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleolus  cytoplasm  cytosol  rRNA processing  rRNA processing  translation  translational initiation  protein targeting  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  rRNA binding  cytosolic large ribosomal subunit  protein localization to nucleus  ribosomal large subunit biogenesis  poly(A) RNA binding  extracellular exosome  
Ontology : EGO-EBIribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleolus  cytoplasm  cytosol  rRNA processing  rRNA processing  translation  translational initiation  protein targeting  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  rRNA binding  cytosolic large ribosomal subunit  protein localization to nucleus  ribosomal large subunit biogenesis  poly(A) RNA binding  extracellular exosome  
Pathways : KEGGRibosome   
NDEx Network
Atlas of Cancer Signalling NetworkRPL11
Wikipedia pathwaysRPL11
Orthology - Evolution
OrthoDB6135
GeneTree (enSembl)ENSG00000142676
Phylogenetic Trees/Animal Genes : TreeFamRPL11
Homologs : HomoloGeneRPL11
Homology/Alignments : Family Browser (UCSC)RPL11
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerRPL11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL11
dbVarRPL11
ClinVarRPL11
1000_GenomesRPL11 
Exome Variant ServerRPL11
ExAC (Exome Aggregation Consortium)RPL11 (select the gene name)
Genetic variants : HAPMAP6135
Genomic Variants (DGV)RPL11 [DGVbeta]
Mutations
ICGC Data PortalRPL11 
TCGA Data PortalRPL11 
Broad Tumor PortalRPL11
OASIS PortalRPL11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL11 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)Diamond-Blackfan Anemia
BioMutasearch RPL11
DgiDB (Drug Gene Interaction Database)RPL11
DoCM (Curated mutations)RPL11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL11 (select a term)
intoGenRPL11
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:24018269-24022915  ENSG00000142676
CONAN: Copy Number AnalysisRPL11 
Mutations and Diseases : HGMDRPL11
OMIM604175    612562   
MedgenRPL11
Genetic Testing Registry RPL11
NextProtP62913 [Medical]
TSGene6135
GENETestsRPL11
Huge Navigator RPL11 [HugePedia]
snp3D : Map Gene to Disease6135
BioCentury BCIQRPL11
ClinGenRPL11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6135
Chemical/Pharm GKB GenePA34664
Clinical trialRPL11
Miscellaneous
canSAR (ICR)RPL11 (select the gene name)
Probes
Litterature
PubMed108 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL11
EVEXRPL11
GoPubMedRPL11
iHOPRPL11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:08:39 CEST 2016

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