RPL15 (ribosomal protein L15)

2003-06-01  

Identity

HGNC
LOCATION
3p24.2
LOCUSID
ALIAS
DBA12,EC45,L15,RPL10,RPLY10,RPYL10
FUSION GENES

Other Information

Locus ID:

NCBI: 6138
MIM: 604174
HGNC: 10306
Ensembl: ENSG00000174748

Variants:

dbSNP: 6138
ClinVar: 6138
TCGA: ENSG00000174748
COSMIC: RPL15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174748ENST00000307839P61313
ENSG00000174748ENST00000307839A0A024R2Q4
ENSG00000174748ENST00000354811P61313
ENSG00000174748ENST00000354811A0A024R2Q4
ENSG00000174748ENST00000412097E7ENU7
ENSG00000174748ENST00000413699P61313
ENSG00000174748ENST00000413699A0A024R2Q4
ENSG00000174748ENST00000415719P61313
ENSG00000174748ENST00000415719A0A024R2Q4
ENSG00000174748ENST00000422218E7EX53
ENSG00000174748ENST00000434031E7EQV9
ENSG00000174748ENST00000436146E7ERA2
ENSG00000174748ENST00000456530P61313
ENSG00000174748ENST00000611050P61313
ENSG00000174748ENST00000611050A0A024R2Q4
ENSG00000174748ENST00000643707A0A2R8Y738
ENSG00000174748ENST00000644185P61313
ENSG00000174748ENST00000644185A0A024R2Q4
ENSG00000174748ENST00000644684E7ERA2
ENSG00000174748ENST00000645079A0A2R8YEM3

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

References

Pubmed IDYearTitleCitations
374312692023Decreased expression of RPL15 and RPL18 exacerbated the calcification of valve interstitial cells during aortic valve calcification.1
374312692023Decreased expression of RPL15 and RPL18 exacerbated the calcification of valve interstitial cells during aortic valve calcification.1
358563932022Detection of mRNAs of Ribosomal Protein L15 and E-Cadherin in Living Circulating Tumor Cells at Single Cell Resolution To Study Tumor Heterogeneity.0
358563932022Detection of mRNAs of Ribosomal Protein L15 and E-Cadherin in Living Circulating Tumor Cells at Single Cell Resolution To Study Tumor Heterogeneity.0
316116232020Circ-RPL15: a plasma circular RNA as novel oncogenic driver to promote progression of chronic lymphocytic leukemia.32
319049962020Identification of Potential Biomarkers for Intervertebral Disc Degeneration Using the Genome-Wide Expression Analysis.1
325598502020Overexpressed circ-RPL15 predicts poor survival and promotes the progression of gastric cancer via regulating miR-502-3p/OLFM4/STAT3 pathway.13
316116232020Circ-RPL15: a plasma circular RNA as novel oncogenic driver to promote progression of chronic lymphocytic leukemia.32
319049962020Identification of Potential Biomarkers for Intervertebral Disc Degeneration Using the Genome-Wide Expression Analysis.1
325598502020Overexpressed circ-RPL15 predicts poor survival and promotes the progression of gastric cancer via regulating miR-502-3p/OLFM4/STAT3 pathway.13
315231762019Ribosomal Protein L15 is involved in Colon Carcinogenesis.25
315231762019Ribosomal Protein L15 is involved in Colon Carcinogenesis.25
295992052018Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.12
295992052018Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia.12
276125572016Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells.19

Citation

Dessen P

RPL15 (ribosomal protein L15)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42150/rpl15