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RPL21 (ribosomal protein L21)

Identity

Alias (NCBI)HYPT12
L21
HGNC (Hugo) RPL21
HGNC Alias symbL21
FLJ27458
MGC71252
MGC104274
MGC104275
DKFZp686C06101
HGNC Alias name60S ribosomal protein L21
LocusID (NCBI) 6144
Atlas_Id 72802
Location 10q26.12  [Link to chromosome band 10q26]
Location_base_pair Starts at 120354661 and ends at 120355223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPL21 (13q12.2) / AHNAK (11q12.3)RPL21 (13q12.2) / ELF3 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RPL21   10313
Cards
Entrez_Gene (NCBI)RPL21    ribosomal protein L21
AliasesHYPT12; L21
GeneCards (Weizmann)RPL21
Ensembl hg19 (Hinxton)ENSG00000122026 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122026 [Gene_View]  ENSG00000122026 [Sequence]  chr10:120354661-120355223 [Contig_View]  RPL21 [Vega]
ICGC DataPortalENSG00000122026
TCGA cBioPortalRPL21
AceView (NCBI)RPL21
Genatlas (Paris)RPL21
SOURCE (Princeton)RPL21
Genetics Home Reference (NIH)RPL21
Genomic and cartography
GoldenPath hg38 (UCSC)RPL21  -     chr10:120354661-120355223 -  10q26.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPL21  -     10q26.12   [Description]    (hg19-Feb_2009)
GoldenPathRPL21 - 10q26.12 [CytoView hg19]  RPL21 - 10q26.12 [CytoView hg38]
ImmunoBaseENSG00000122026
Genome Data Viewer NCBIRPL21 [Mapview hg19]  
OMIM603636   615885   
Gene and transcription
Genbank (Entrez)AF086172 AK130968 AK311795 AY320407 BC001603
RefSeq transcript (Entrez)NM_000982
Consensus coding sequences : CCDS (NCBI)RPL21
Gene ExpressionRPL21 [ NCBI-GEO ]   RPL21 [ EBI - ARRAY_EXPRESS ]   RPL21 [ SEEK ]   RPL21 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL21 [ Firebrowse - Broad ]
GenevisibleExpression of RPL21 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6144
GTEX Portal (Tissue expression)RPL21
Human Protein AtlasENSG00000122026-RPL21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46778   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46778  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46778
PhosPhoSitePlusP46778
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L21E (PS01171)   
Domains : Interpro (EBI)Ribosomal_L21_sf    Ribosomal_L21e    Ribosomal_L21e_CS    Translation_prot_SH3-like_sf   
Domain families : Pfam (Sanger)Ribosomal_L21e (PF01157)   
Domain families : Pfam (NCBI)pfam01157   
Conserved Domain (NCBI)RPL21
PDB (RSDB)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB Europe4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB (PDBSum)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB (IMB)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
Structural Biology KnowledgeBase4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
CATH (Classification of proteins structures)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
SuperfamilyP46778
AlphaFold pdb e-kbP46778   
Human Protein Atlas [tissue]ENSG00000122026-RPL21 [tissue]
HPRD04700
Protein Interaction databases
DIP (DOE-UCLA)P46778
IntAct (EBI)P46778
BioGRIDRPL21
STRING (EMBL)RPL21
ZODIACRPL21
Ontologies - Pathways
QuickGOP46778
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  endoplasmic reticulum  cytosol  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic ribosome  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  endoplasmic reticulum  cytosol  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic ribosome  
Pathways : KEGGRibosome   
NDEx NetworkRPL21
Atlas of Cancer Signalling NetworkRPL21
Wikipedia pathwaysRPL21
Orthology - Evolution
OrthoDB6144
GeneTree (enSembl)ENSG00000122026
Phylogenetic Trees/Animal Genes : TreeFamRPL21
Homologs : HomoloGeneRPL21
Homology/Alignments : Family Browser (UCSC)RPL21
Gene fusions - Rearrangements
Fusion : QuiverRPL21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL21
dbVarRPL21
ClinVarRPL21
MonarchRPL21
1000_GenomesRPL21 
Exome Variant ServerRPL21
GNOMAD BrowserENSG00000122026
Varsome BrowserRPL21
ACMGRPL21 variants
VarityP46778
Genomic Variants (DGV)RPL21 [DGVbeta]
DECIPHERRPL21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPL21 
Mutations
ICGC Data PortalRPL21 
TCGA Data PortalRPL21 
Broad Tumor PortalRPL21
OASIS PortalRPL21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL21  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRPL21
Mutations and Diseases : HGMDRPL21
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRPL21
DgiDB (Drug Gene Interaction Database)RPL21
DoCM (Curated mutations)RPL21
CIViC (Clinical Interpretations of Variants in Cancer)RPL21
Cancer3DRPL21
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603636    615885   
Orphanet10760   
DisGeNETRPL21
MedgenRPL21
Genetic Testing Registry RPL21
NextProtP46778 [Medical]
GENETestsRPL21
Target ValidationRPL21
Huge Navigator RPL21 [HugePedia]
ClinGenRPL21
Clinical trials, drugs, therapy
MyCancerGenomeRPL21
Protein Interactions : CTDRPL21
Pharm GKB GenePA34683
PharosP46778
Clinical trialRPL21
Miscellaneous
canSAR (ICR)RPL21
HarmonizomeRPL21
DataMed IndexRPL21
Probes
Litterature
PubMed118 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRPL21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:19:11 CEST 2021

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