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RPL23A (ribosomal protein L23a)

Identity

Alias_symbol (synonym)L23A
Other aliasMDA20
HGNC (Hugo) RPL23A
LocusID (NCBI) 6147
Atlas_Id 56330
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 27047000 and ends at 27051374 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCDC43 (17q21.31) / RPL23A (17q11.2)CMYA5 (5q14.1) / RPL23A (17q11.2)RPL23A (17q11.2) / NAA15 (4q31.1)
RPL23A (17q11.2) / SPEF2 (5p13.2)RPL23A (17q11.2) / UBC (12q24.31)TRBV20-1 () / RPL23A (17q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPL23A   10317
Cards
Entrez_Gene (NCBI)RPL23A  6147  ribosomal protein L23a
AliasesL23A; MDA20
GeneCards (Weizmann)RPL23A
Ensembl hg19 (Hinxton)ENSG00000198242 [Gene_View]  chr17:27047000-27051374 [Contig_View]  RPL23A [Vega]
Ensembl hg38 (Hinxton)ENSG00000198242 [Gene_View]  chr17:27047000-27051374 [Contig_View]  RPL23A [Vega]
ICGC DataPortalENSG00000198242
TCGA cBioPortalRPL23A
AceView (NCBI)RPL23A
Genatlas (Paris)RPL23A
WikiGenes6147
SOURCE (Princeton)RPL23A
Genetics Home Reference (NIH)RPL23A
Genomic and cartography
GoldenPath hg19 (UCSC)RPL23A  -     chr17:27047000-27051374 +  17q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RPL23A  -     17q11.2   [Description]    (hg38-Dec_2013)
EnsemblRPL23A - 17q11.2 [CytoView hg19]  RPL23A - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBIRPL23A [Mapview hg19]  RPL23A [Mapview hg38]
OMIM602326   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_000984
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPL23A
Cluster EST : UnigeneHs.419463 [ NCBI ]
CGAP (NCI)Hs.419463
Alternative Splicing GalleryENSG00000198242
Gene ExpressionRPL23A [ NCBI-GEO ]   RPL23A [ EBI - ARRAY_EXPRESS ]   RPL23A [ SEEK ]   RPL23A [ MEM ]
Gene Expression Viewer (FireBrowse)RPL23A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6147
GTEX Portal (Tissue expression)RPL23A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62750   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62750  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62750
Splice isoforms : SwissVarP62750
PhosPhoSitePlusP62750
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L23 (PS00050)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    Ribosomal_L23    Ribosomal_L23/L15e_core_dom    Ribosomal_L23/L25_CS    Ribosomal_L23/L25_N    Ribosomal_L25/23   
Domain families : Pfam (Sanger)Ribosomal_L23 (PF00276)    Ribosomal_L23eN (PF03939)   
Domain families : Pfam (NCBI)pfam00276    pfam03939   
Conserved Domain (NCBI)RPL23A
DMDM Disease mutations6147
Blocks (Seattle)RPL23A
PDB (SRS)4UG0    4V6X    5AJ0   
PDB (PDBSum)4UG0    4V6X    5AJ0   
PDB (IMB)4UG0    4V6X    5AJ0   
PDB (RSDB)4UG0    4V6X    5AJ0   
Structural Biology KnowledgeBase4UG0    4V6X    5AJ0   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5AJ0   
CATH (Classification of proteins structures)4UG0    4V6X    5AJ0   
SuperfamilyP62750
Human Protein AtlasENSG00000198242
Peptide AtlasP62750
HPRD15998
IPIIPI00021266   IPI00794894   IPI00793523   IPI00789159   
Protein Interaction databases
DIP (DOE-UCLA)P62750
IntAct (EBI)P62750
FunCoupENSG00000198242
BioGRIDRPL23A
STRING (EMBL)RPL23A
ZODIACRPL23A
Ontologies - Pathways
QuickGOP62750
Ontology : AmiGOribosomal large subunit assembly  nucleotide binding  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  cell-cell adherens junction  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  cell proliferation  viral transcription  rRNA binding  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  TORC2 complex  poly(A) RNA binding  extracellular exosome  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  
Ontology : EGO-EBIribosomal large subunit assembly  nucleotide binding  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  cell-cell adherens junction  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  cell proliferation  viral transcription  rRNA binding  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  TORC2 complex  poly(A) RNA binding  extracellular exosome  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  
Pathways : KEGGRibosome   
NDEx NetworkRPL23A
Atlas of Cancer Signalling NetworkRPL23A
Wikipedia pathwaysRPL23A
Orthology - Evolution
OrthoDB6147
GeneTree (enSembl)ENSG00000198242
Phylogenetic Trees/Animal Genes : TreeFamRPL23A
HOVERGENP62750
HOGENOMP62750
Homologs : HomoloGeneRPL23A
Homology/Alignments : Family Browser (UCSC)RPL23A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL23A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL23A
dbVarRPL23A
ClinVarRPL23A
1000_GenomesRPL23A 
Exome Variant ServerRPL23A
ExAC (Exome Aggregation Consortium)RPL23A (select the gene name)
Genetic variants : HAPMAP6147
Genomic Variants (DGV)RPL23A [DGVbeta]
DECIPHER (Syndromes)17:27047000-27051374  ENSG00000198242
CONAN: Copy Number AnalysisRPL23A 
Mutations
ICGC Data PortalRPL23A 
TCGA Data PortalRPL23A 
Broad Tumor PortalRPL23A
OASIS PortalRPL23A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL23A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPL23A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPL23A
DgiDB (Drug Gene Interaction Database)RPL23A
DoCM (Curated mutations)RPL23A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL23A (select a term)
intoGenRPL23A
Cancer3DRPL23A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602326   
Orphanet
MedgenRPL23A
Genetic Testing Registry RPL23A
NextProtP62750 [Medical]
TSGene6147
GENETestsRPL23A
Huge Navigator RPL23A [HugePedia]
snp3D : Map Gene to Disease6147
BioCentury BCIQRPL23A
ClinGenRPL23A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6147
Chemical/Pharm GKB GenePA34691
Clinical trialRPL23A
Miscellaneous
canSAR (ICR)RPL23A (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL23A
EVEXRPL23A
GoPubMedRPL23A
iHOPRPL23A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:17:53 CEST 2017

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