RPL27 (ribosomal protein L27)

2003-08-01  

Identity

HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
DBA16,L27
FUSION GENES

Other Information

Locus ID:

NCBI: 6155
MIM: 607526
HGNC: 10328
Ensembl: ENSG00000131469

Variants:

dbSNP: 6155
ClinVar: 6155
TCGA: ENSG00000131469
COSMIC: RPL27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131469ENST00000253788P61353
ENSG00000131469ENST00000253788A0A024R1V4
ENSG00000131469ENST00000586277K7ELC7
ENSG00000131469ENST00000588830K7ERY7
ENSG00000131469ENST00000589037P61353
ENSG00000131469ENST00000589037A0A024R1V4
ENSG00000131469ENST00000589913P61353
ENSG00000131469ENST00000589913A0A024R1V4
ENSG00000131469ENST00000590864K7EQQ9

Expression (GTEx)

0
500
1000
1500
2000

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Ribosome, eukaryotesKEGGhsa_M00177
Ribosome, eukaryotesKEGGM00177
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
Eukaryotic Translation InitiationREACTOMER-HSA-72613
Cap-dependent Translation InitiationREACTOMER-HSA-72737
Formation of a pool of free 40S subunitsREACTOMER-HSA-72689
GTP hydrolysis and joining of the 60S ribosomal subunitREACTOMER-HSA-72706
L13a-mediated translational silencing of Ceruloplasmin expressionREACTOMER-HSA-156827
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Eukaryotic Translation ElongationREACTOMER-HSA-156842
Peptide chain elongationREACTOMER-HSA-156902
Eukaryotic Translation TerminationREACTOMER-HSA-72764
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Influenza InfectionREACTOMER-HSA-168254
Influenza Life CycleREACTOMER-HSA-168255
Influenza Viral RNA Transcription and ReplicationREACTOMER-HSA-168273
Viral mRNA TranslationREACTOMER-HSA-192823
Gene ExpressionREACTOMER-HSA-74160
Nonsense-Mediated Decay (NMD)REACTOMER-HSA-927802
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)REACTOMER-HSA-975957
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)REACTOMER-HSA-975956
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Selenoamino acid metabolismREACTOMER-HSA-2408522
Selenocysteine synthesisREACTOMER-HSA-2408557
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
254249022015Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.34

Citation

Dessen P

RPL27 (ribosomal protein L27)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/42152/rpl27