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RPL3 (ribosomal protein L3)

Identity

Alias_symbol (synonym)L3
Other aliasASC-1
TARBP-B
HGNC (Hugo) RPL3
LocusID (NCBI) 6122
Atlas_Id 55440
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39312882 and ends at 39319665 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EMILIN1 (2p23.3) / RPL3 (22q13.1)FLT3LG (19q13.33) / RPL3 (22q13.1)GPX1 (3p21.31) / RPL3 (22q13.1)
HLA-B (6p21.33) / RPL3 (22q13.1)LPAR5 (12p13.31) / RPL3 (22q13.1)MICB (6p21.33) / RPL3 (22q13.1)
NGLY1 (3p24.2) / RPL3 (22q13.1)PLPP5 (8p11.23) / RPL3 (22q13.1)RPL3 (22q13.1) / BCL2L2-PABPN1 (14q11.2)
RPL3 (22q13.1) / MALSU1 (7p15.3)RPL3 (22q13.1) / RPL3 (22q13.1)RPL3 (22q13.1) / SOX8 (16p13.3)
RPL3 (22q13.1) / STX11 (6q24.2)RPL38 (17q25.1) / RPL3 (22q13.1)SEPT11 (4q21.1) / RPL3 (22q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPL3   10332
Cards
Entrez_Gene (NCBI)RPL3  6122  ribosomal protein L3
AliasesASC-1; L3; TARBP-B
GeneCards (Weizmann)RPL3
Ensembl hg19 (Hinxton)ENSG00000100316 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100316 [Gene_View]  chr22:39312882-39319665 [Contig_View]  RPL3 [Vega]
ICGC DataPortalENSG00000100316
TCGA cBioPortalRPL3
AceView (NCBI)RPL3
Genatlas (Paris)RPL3
WikiGenes6122
SOURCE (Princeton)RPL3
Genetics Home Reference (NIH)RPL3
Genomic and cartography
GoldenPath hg38 (UCSC)RPL3  -     chr22:39312882-39319665 -  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPL3  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblRPL3 - 22q13.1 [CytoView hg19]  RPL3 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIRPL3 [Mapview hg19]  RPL3 [Mapview hg38]
OMIM604163   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_000967 NM_001033853
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPL3
Cluster EST : UnigeneHs.119598 [ NCBI ]
CGAP (NCI)Hs.119598
Alternative Splicing GalleryENSG00000100316
Gene ExpressionRPL3 [ NCBI-GEO ]   RPL3 [ EBI - ARRAY_EXPRESS ]   RPL3 [ SEEK ]   RPL3 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6122
GTEX Portal (Tissue expression)RPL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP39023   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP39023  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP39023
Splice isoforms : SwissVarP39023
PhosPhoSitePlusP39023
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L3 (PS00474)   
Domains : Interpro (EBI)Ribosomal_L3    Ribosomal_L3_CS    Transl_B-barrel   
Domain families : Pfam (Sanger)Ribosomal_L3 (PF00297)   
Domain families : Pfam (NCBI)pfam00297   
Conserved Domain (NCBI)RPL3
DMDM Disease mutations6122
Blocks (Seattle)RPL3
PDB (SRS)4UG0    4V6X    5AJ0    5T2C   
PDB (PDBSum)4UG0    4V6X    5AJ0    5T2C   
PDB (IMB)4UG0    4V6X    5AJ0    5T2C   
PDB (RSDB)4UG0    4V6X    5AJ0    5T2C   
Structural Biology KnowledgeBase4UG0    4V6X    5AJ0    5T2C   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5AJ0    5T2C   
CATH (Classification of proteins structures)4UG0    4V6X    5AJ0    5T2C   
SuperfamilyP39023
Human Protein AtlasENSG00000100316
Peptide AtlasP39023
HPRD16042
IPIIPI00550021   IPI00385352   IPI00651660   IPI00877635   IPI00877787   IPI00878524   IPI00877999   IPI00878827   
Protein Interaction databases
DIP (DOE-UCLA)P39023
IntAct (EBI)P39023
FunCoupENSG00000100316
BioGRIDRPL3
STRING (EMBL)RPL3
ZODIACRPL3
Ontologies - Pathways
QuickGOP39023
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  cytosol  focal adhesion  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  5S rRNA binding  viral transcription  cytosolic large ribosomal subunit  extracellular exosome  cellular response to interleukin-4  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  cytosol  focal adhesion  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  5S rRNA binding  viral transcription  cytosolic large ribosomal subunit  extracellular exosome  cellular response to interleukin-4  
Pathways : KEGGRibosome   
NDEx NetworkRPL3
Atlas of Cancer Signalling NetworkRPL3
Wikipedia pathwaysRPL3
Orthology - Evolution
OrthoDB6122
GeneTree (enSembl)ENSG00000100316
Phylogenetic Trees/Animal Genes : TreeFamRPL3
HOVERGENP39023
HOGENOMP39023
Homologs : HomoloGeneRPL3
Homology/Alignments : Family Browser (UCSC)RPL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL3
dbVarRPL3
ClinVarRPL3
1000_GenomesRPL3 
Exome Variant ServerRPL3
ExAC (Exome Aggregation Consortium)RPL3 (select the gene name)
Genetic variants : HAPMAP6122
Genomic Variants (DGV)RPL3 [DGVbeta]
DECIPHERRPL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPL3 
Mutations
ICGC Data PortalRPL3 
TCGA Data PortalRPL3 
Broad Tumor PortalRPL3
OASIS PortalRPL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPL3
DgiDB (Drug Gene Interaction Database)RPL3
DoCM (Curated mutations)RPL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL3 (select a term)
intoGenRPL3
Cancer3DRPL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604163   
Orphanet
MedgenRPL3
Genetic Testing Registry RPL3
NextProtP39023 [Medical]
TSGene6122
GENETestsRPL3
Target ValidationRPL3
Huge Navigator RPL3 [HugePedia]
snp3D : Map Gene to Disease6122
BioCentury BCIQRPL3
ClinGenRPL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6122
Chemical/Pharm GKB GenePA34713
Clinical trialRPL3
Miscellaneous
canSAR (ICR)RPL3 (select the gene name)
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL3
EVEXRPL3
GoPubMedRPL3
iHOPRPL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:53:48 CEST 2017

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