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RPL4 (ribosomal protein L4)

Identity

Alias_symbol (synonym)L4
Other alias
HGNC (Hugo) RPL4
LocusID (NCBI) 6124
Atlas_Id 72836
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 66791653 and ends at 66797193 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDK4 (12q14.1) / RPL4 (15q22.31)RPL4 (15q22.31) / ACTN1 (14q24.1)RPL4 (15q22.31) / HS6ST3 (13q32.1)
RPL4 (15q22.31) / KRT222 (17q21.2)RPL4 (15q22.31) / LOC100505761 ()RPL4 (15q22.31) / LOC653739 ()
RPL4 (15q22.31) / OGFOD2 (12q24.31)SPCS1 (3p21.1) / RPL4 (15q22.31)TMSB10 (2p11.2) / RPL4 (15q22.31)
TMTC3 (12q21.32) / RPL4 (15q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPL4   10353
Cards
Entrez_Gene (NCBI)RPL4  6124  ribosomal protein L4
AliasesL4
GeneCards (Weizmann)RPL4
Ensembl hg19 (Hinxton) [Gene_View]  chr15:66791653-66797193 [Contig_View]  RPL4 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr15:66791653-66797193 [Contig_View]  RPL4 [Vega]
TCGA cBioPortalRPL4
AceView (NCBI)RPL4
Genatlas (Paris)RPL4
WikiGenes6124
SOURCE (Princeton)RPL4
Genetics Home Reference (NIH)RPL4
Genomic and cartography
GoldenPath hg19 (UCSC)RPL4  -     chr15:66791653-66797193 -  15q22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RPL4  -     15q22.31   [Description]    (hg38-Dec_2013)
EnsemblRPL4 - 15q22.31 [CytoView hg19]  RPL4 - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIRPL4 [Mapview hg19]  RPL4 [Mapview hg38]
OMIM180479   
Gene and transcription
Genbank (Entrez)AB208977 AK125772 AK130784 AK223057 AK291117
RefSeq transcript (Entrez)NM_000968
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)RPL4
Cluster EST : UnigeneHs.644628 [ NCBI ]
CGAP (NCI)Hs.644628
Gene ExpressionRPL4 [ NCBI-GEO ]   RPL4 [ EBI - ARRAY_EXPRESS ]   RPL4 [ SEEK ]   RPL4 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6124
GTEX Portal (Tissue expression)RPL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36578   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36578  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36578
Splice isoforms : SwissVarP36578
PhosPhoSitePlusP36578
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L1E (PS00939)   
Domains : Interpro (EBI)Ribos_L4_C_dom    Ribosomal_L4/L1e    Ribosomal_L4/L1e_euk/arc_CS    Ribosomal_L4_dom   
Domain families : Pfam (Sanger)Ribos_L4_asso_C (PF14374)    Ribosomal_L4 (PF00573)   
Domain families : Pfam (NCBI)pfam14374    pfam00573   
Conserved Domain (NCBI)RPL4
DMDM Disease mutations6124
Blocks (Seattle)RPL4
PDB (SRS)4V6X   
PDB (PDBSum)4V6X   
PDB (IMB)4V6X   
PDB (RSDB)4V6X   
Structural Biology KnowledgeBase4V6X   
SCOP (Structural Classification of Proteins)4V6X   
CATH (Classification of proteins structures)4V6X   
SuperfamilyP36578
Peptide AtlasP36578
HPRD01607
IPIIPI00003918   IPI00908662   IPI00795303   IPI00908376   
Protein Interaction databases
DIP (DOE-UCLA)P36578
IntAct (EBI)P36578
BioGRIDRPL4
STRING (EMBL)RPL4
ZODIACRPL4
Ontologies - Pathways
QuickGOP36578
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  focal adhesion  translation  translation  translational initiation  translational elongation  translational termination  SRP-dependent cotranslational protein targeting to membrane  gene expression  membrane  viral process  viral life cycle  viral transcription  cytosolic large ribosomal subunit  ribonucleoprotein complex  cellular protein metabolic process  poly(A) RNA binding  extracellular exosome  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleus  nucleolus  cytoplasm  cytosol  focal adhesion  translation  translation  translational initiation  translational elongation  translational termination  SRP-dependent cotranslational protein targeting to membrane  gene expression  membrane  viral process  viral life cycle  viral transcription  cytosolic large ribosomal subunit  ribonucleoprotein complex  cellular protein metabolic process  poly(A) RNA binding  extracellular exosome  
Pathways : KEGGRibosome   
NDEx NetworkRPL4
Atlas of Cancer Signalling NetworkRPL4
Wikipedia pathwaysRPL4
Orthology - Evolution
OrthoDB6124
Phylogenetic Trees/Animal Genes : TreeFamRPL4
HOVERGENP36578
HOGENOMP36578
Homologs : HomoloGeneRPL4
Homology/Alignments : Family Browser (UCSC)RPL4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL4
dbVarRPL4
ClinVarRPL4
1000_GenomesRPL4 
Exome Variant ServerRPL4
ExAC (Exome Aggregation Consortium)RPL4 (select the gene name)
Genetic variants : HAPMAP6124
Genomic Variants (DGV)RPL4 [DGVbeta]
DECIPHER (Syndromes)15:66791653-66797193  
CONAN: Copy Number AnalysisRPL4 
Mutations
ICGC Data PortalRPL4 
TCGA Data PortalRPL4 
Broad Tumor PortalRPL4
OASIS PortalRPL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPL4
DgiDB (Drug Gene Interaction Database)RPL4
DoCM (Curated mutations)RPL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL4 (select a term)
intoGenRPL4
Cancer3DRPL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180479   
Orphanet
MedgenRPL4
Genetic Testing Registry RPL4
NextProtP36578 [Medical]
TSGene6124
GENETestsRPL4
Huge Navigator RPL4 [HugePedia]
snp3D : Map Gene to Disease6124
BioCentury BCIQRPL4
ClinGenRPL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6124
Chemical/Pharm GKB GenePA34749
Clinical trialRPL4
Miscellaneous
canSAR (ICR)RPL4 (select the gene name)
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL4
EVEXRPL4
GoPubMedRPL4
iHOPRPL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:41:47 CET 2017

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