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RPL6 (ribosomal protein L6)

Identity

Alias (NCBI)L6
SHUJUN-2
TAXREB107
TXREB1
HGNC (Hugo) RPL6
HGNC Alias symbTAXREB107
L6
HGNC Previous nameTXREB1
LocusID (NCBI) 6128
Atlas_Id 42158
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 112405181 and ends at 112411442 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATXN2 (12q24.12) / RPL6 (12q24.13)CTGF (6q23.2) / RPL6 (12q24.13)HTN3 (4q13.3) / RPL6 (12q24.13)
NEURL1B (5q35.1) / RPL6 (12q24.13)YLPM1 (14q24.3) / RPL6 (12q24.13)ZNF521 (18q11.2) / RPL6 (12q24.13)
ATXN2 12q24.12 / RPL6 12q24.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RPL6   10362
Cards
Entrez_Gene (NCBI)RPL6    ribosomal protein L6
AliasesL6; SHUJUN-2; TAXREB107; TXREB1
GeneCards (Weizmann)RPL6
Ensembl hg19 (Hinxton)ENSG00000089009 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089009 [Gene_View]  ENSG00000089009 [Sequence]  chr12:112405181-112411442 [Contig_View]  RPL6 [Vega]
ICGC DataPortalENSG00000089009
TCGA cBioPortalRPL6
AceView (NCBI)RPL6
Genatlas (Paris)RPL6
SOURCE (Princeton)RPL6
Genetics Home Reference (NIH)RPL6
Genomic and cartography
GoldenPath hg38 (UCSC)RPL6  -     chr12:112405181-112411442 -  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPL6  -     12q24.13   [Description]    (hg19-Feb_2009)
GoldenPathRPL6 - 12q24.13 [CytoView hg19]  RPL6 - 12q24.13 [CytoView hg38]
ImmunoBaseENSG00000089009
Genome Data Viewer NCBIRPL6 [Mapview hg19]  
OMIM603703   
Gene and transcription
Genbank (Entrez)AF261087 AI583261 AK298117 AK299470 AK308469
RefSeq transcript (Entrez)NM_000970 NM_001024662 NM_001320137 NM_001320138 NM_001320139 NM_001320140 NM_001320141 NM_001320142
Consensus coding sequences : CCDS (NCBI)RPL6
Gene ExpressionRPL6 [ NCBI-GEO ]   RPL6 [ EBI - ARRAY_EXPRESS ]   RPL6 [ SEEK ]   RPL6 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL6 [ Firebrowse - Broad ]
GenevisibleExpression of RPL6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6128
GTEX Portal (Tissue expression)RPL6
Human Protein AtlasENSG00000089009-RPL6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02878   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02878  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02878
PhosPhoSitePlusQ02878
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L6E (PS01170)   
Domains : Interpro (EBI)60S_ribosomal_L6E    KOW_RPL6    Rib_L2_dom2    Ribosomal_L6_N    Translation_prot_SH3-like_sf   
Domain families : Pfam (Sanger)Ribosomal_L6e (PF01159)    Ribosomal_L6e_N (PF03868)   
Domain families : Pfam (NCBI)pfam01159    pfam03868   
Conserved Domain (NCBI)RPL6
PDB (RSDB)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB Europe4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB (PDBSum)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
PDB (IMB)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
Structural Biology KnowledgeBase4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
CATH (Classification of proteins structures)4UG0    4V6X    5AJ0    5LKS    5T2C    6EK0    6IP5    6IP6    6IP8    6LQM    6LSR    6LSS    6LU8    6OLE    6OLF    6OLG    6OLI    6OLZ    6OM0    6OM7    6QZP    6W6L    6XA1    6Y0G    6Y2L    6Y57    6Y6X    6Z6L    6Z6M    6Z6N    6ZM7    6ZME    6ZMI    6ZMO   
SuperfamilyQ02878
AlphaFold pdb e-kbQ02878   
Human Protein Atlas [tissue]ENSG00000089009-RPL6 [tissue]
HPRD04745
Protein Interaction databases
DIP (DOE-UCLA)Q02878
IntAct (EBI)Q02878
BioGRIDRPL6
STRING (EMBL)RPL6
ZODIACRPL6
Ontologies - Pathways
QuickGOQ02878
Ontology : AmiGOribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  cytoplasmic translation  cytoplasmic translation  DNA binding  RNA binding  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  nucleus  rough endoplasmic reticulum  cytosol  focal adhesion  regulation of transcription, DNA-templated  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic ribosome  cytoplasmic ribonucleoprotein granule  polysomal ribosome  cadherin binding  
Ontology : EGO-EBIribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  cytoplasmic translation  cytoplasmic translation  DNA binding  RNA binding  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  nucleus  rough endoplasmic reticulum  cytosol  focal adhesion  regulation of transcription, DNA-templated  rRNA processing  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic ribosome  cytoplasmic ribonucleoprotein granule  polysomal ribosome  cadherin binding  
Pathways : KEGGRibosome   
NDEx NetworkRPL6
Atlas of Cancer Signalling NetworkRPL6
Wikipedia pathwaysRPL6
Orthology - Evolution
OrthoDB6128
GeneTree (enSembl)ENSG00000089009
Phylogenetic Trees/Animal Genes : TreeFamRPL6
Homologs : HomoloGeneRPL6
Homology/Alignments : Family Browser (UCSC)RPL6
Gene fusions - Rearrangements
Fusion : MitelmanATXN2/RPL6 [12q24.12/12q24.13]  
Fusion : QuiverRPL6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL6
dbVarRPL6
ClinVarRPL6
MonarchRPL6
1000_GenomesRPL6 
Exome Variant ServerRPL6
GNOMAD BrowserENSG00000089009
Varsome BrowserRPL6
ACMGRPL6 variants
VarityQ02878
Genomic Variants (DGV)RPL6 [DGVbeta]
DECIPHERRPL6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPL6 
Mutations
ICGC Data PortalRPL6 
TCGA Data PortalRPL6 
Broad Tumor PortalRPL6
OASIS PortalRPL6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRPL6
Mutations and Diseases : HGMDRPL6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRPL6
DgiDB (Drug Gene Interaction Database)RPL6
DoCM (Curated mutations)RPL6
CIViC (Clinical Interpretations of Variants in Cancer)RPL6
Cancer3DRPL6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603703   
Orphanet
DisGeNETRPL6
MedgenRPL6
Genetic Testing Registry RPL6
NextProtQ02878 [Medical]
GENETestsRPL6
Target ValidationRPL6
Huge Navigator RPL6 [HugePedia]
ClinGenRPL6
Clinical trials, drugs, therapy
MyCancerGenomeRPL6
Protein Interactions : CTDRPL6
Pharm GKB GenePA34758
PharosQ02878
Clinical trialRPL6
Miscellaneous
canSAR (ICR)RPL6
HarmonizomeRPL6
DataMed IndexRPL6
Probes
Litterature
PubMed173 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRPL6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:31 CEST 2021

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