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RPL7L1 (ribosomal protein L7 like 1)

Identity

Alias_namesribosomal protein L7-like 1
Alias_symbol (synonym)dJ475N16.4
Other alias
HGNC (Hugo) RPL7L1
LocusID (NCBI) 285855
Atlas_Id 54591
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 42879616 and ends at 42889896 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPL7L1 (6p21.1) / CDK8 (13q12.13)RPL7L1 (6p21.1) / CRYBB2P1 (22q11.23)RPL7L1 (6p21.1) / MXRA7 (17q25.1)
SEMA4A (1q22) / RPL7L1 (6p21.1)UGDH (4p14) / RPL7L1 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(6;13)(p21;q12) RPL7L1/CDK8


External links

Nomenclature
HGNC (Hugo)RPL7L1   21370
Cards
Entrez_Gene (NCBI)RPL7L1  285855  ribosomal protein L7 like 1
AliasesdJ475N16.4
GeneCards (Weizmann)RPL7L1
Ensembl hg19 (Hinxton)ENSG00000146223 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146223 [Gene_View]  ENSG00000146223 [Sequence]  chr6:42879616-42889896 [Contig_View]  RPL7L1 [Vega]
ICGC DataPortalENSG00000146223
TCGA cBioPortalRPL7L1
AceView (NCBI)RPL7L1
Genatlas (Paris)RPL7L1
WikiGenes285855
SOURCE (Princeton)RPL7L1
Genetics Home Reference (NIH)RPL7L1
Genomic and cartography
GoldenPath hg38 (UCSC)RPL7L1  -     chr6:42879616-42889896 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPL7L1  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblRPL7L1 - 6p21.1 [CytoView hg19]  RPL7L1 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIRPL7L1 [Mapview hg19]  RPL7L1 [Mapview hg38]
OMIM617417   
Gene and transcription
Genbank (Entrez)AK021904 AK074339 AK091341 AK098059 AK291310
RefSeq transcript (Entrez)NM_001366481 NM_198486
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPL7L1
Cluster EST : UnigeneHs.520133 [ NCBI ]
CGAP (NCI)Hs.520133
Alternative Splicing GalleryENSG00000146223
Gene ExpressionRPL7L1 [ NCBI-GEO ]   RPL7L1 [ EBI - ARRAY_EXPRESS ]   RPL7L1 [ SEEK ]   RPL7L1 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL7L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285855
GTEX Portal (Tissue expression)RPL7L1
Human Protein AtlasENSG00000146223-RPL7L1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6DKI1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6DKI1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6DKI1
Splice isoforms : SwissVarQ6DKI1
PhosPhoSitePlusQ6DKI1
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L30 (PS00634)   
Domains : Interpro (EBI)L30_ferredoxin-like_sf    Ribosomal_L30_central_dom_arc    Ribosomal_L30_CS    Ribosomal_L30_ferredoxin-like    Ribosomal_L30_N    Ribosomal_L7_euk    Ribosomal_L7_euk_arc   
Domain families : Pfam (Sanger)Ribosomal_L30 (PF00327)    Ribosomal_L30_N (PF08079)   
Domain families : Pfam (NCBI)pfam00327    pfam08079   
Conserved Domain (NCBI)RPL7L1
DMDM Disease mutations285855
Blocks (Seattle)RPL7L1
SuperfamilyQ6DKI1
Human Protein Atlas [tissue]ENSG00000146223-RPL7L1 [tissue]
Peptide AtlasQ6DKI1
HPRD18000
IPIIPI00456940   IPI01013442   
Protein Interaction databases
DIP (DOE-UCLA)Q6DKI1
IntAct (EBI)Q6DKI1
FunCoupENSG00000146223
BioGRIDRPL7L1
STRING (EMBL)RPL7L1
ZODIACRPL7L1
Ontologies - Pathways
QuickGOQ6DKI1
Ontology : AmiGOmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  blastocyst formation  RNA binding  structural constituent of ribosome  nucleolus  cytosolic large ribosomal subunit  
Ontology : EGO-EBImaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  blastocyst formation  RNA binding  structural constituent of ribosome  nucleolus  cytosolic large ribosomal subunit  
NDEx NetworkRPL7L1
Atlas of Cancer Signalling NetworkRPL7L1
Wikipedia pathwaysRPL7L1
Orthology - Evolution
OrthoDB285855
GeneTree (enSembl)ENSG00000146223
Phylogenetic Trees/Animal Genes : TreeFamRPL7L1
HOVERGENQ6DKI1
HOGENOMQ6DKI1
Homologs : HomoloGeneRPL7L1
Homology/Alignments : Family Browser (UCSC)RPL7L1
Gene fusions - Rearrangements
Fusion : MitelmanRPL7L1/CDK8 [6p21.1/13q12.13]  
Fusion : QuiverRPL7L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL7L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL7L1
dbVarRPL7L1
ClinVarRPL7L1
1000_GenomesRPL7L1 
Exome Variant ServerRPL7L1
ExAC (Exome Aggregation Consortium)ENSG00000146223
GNOMAD BrowserENSG00000146223
Varsome BrowserRPL7L1
Genetic variants : HAPMAP285855
Genomic Variants (DGV)RPL7L1 [DGVbeta]
DECIPHERRPL7L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPL7L1 
Mutations
ICGC Data PortalRPL7L1 
TCGA Data PortalRPL7L1 
Broad Tumor PortalRPL7L1
OASIS PortalRPL7L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL7L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPL7L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPL7L1
DgiDB (Drug Gene Interaction Database)RPL7L1
DoCM (Curated mutations)RPL7L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL7L1 (select a term)
intoGenRPL7L1
Cancer3DRPL7L1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617417   
Orphanet
DisGeNETRPL7L1
MedgenRPL7L1
Genetic Testing Registry RPL7L1
NextProtQ6DKI1 [Medical]
TSGene285855
GENETestsRPL7L1
Target ValidationRPL7L1
Huge Navigator RPL7L1 [HugePedia]
snp3D : Map Gene to Disease285855
BioCentury BCIQRPL7L1
ClinGenRPL7L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285855
Chemical/Pharm GKB GenePA134977157
Clinical trialRPL7L1
Miscellaneous
canSAR (ICR)RPL7L1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL7L1
EVEXRPL7L1
GoPubMedRPL7L1
iHOPRPL7L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:36:27 CET 2018

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