Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RPN1 (ribophorin I)

Identity

Other namesOST1
RBPH1
HGNC (Hugo) RPN1
LocusID (NCBI) 6184
Location 3q21.3
Location_base_pair Starts at 128338813 and ends at 128369719 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Breakpoints

 

Other Leukemias implicated (Data extracted from papers in the Atlas)

Leukemias 11q23ChildAMLID1615

Other Solid tumors implicated (Data extracted from papers in the Atlas)

Solid Tumors AmeloblastomID5945

External links

Nomenclature
HGNC (Hugo)RPN1   10381
Cards
Entrez_Gene (NCBI)RPN1  6184  ribophorin I
GeneCards (Weizmann)RPN1
Ensembl (Hinxton)ENSG00000163902 [Gene_View]  chr3:128338813-128369719 [Contig_View]  RPN1 [Vega]
ICGC DataPortalENSG00000163902
cBioPortalRPN1
AceView (NCBI)RPN1
Genatlas (Paris)RPN1
WikiGenes6184
SOURCE (Princeton)NM_002950
Genomic and cartography
GoldenPath (UCSC)RPN1  -  3q21.3   chr3:128338813-128369719 -  3q21.3   [Description]    (hg19-Feb_2009)
EnsemblRPN1 - 3q21.3 [CytoView]
Mapping of homologs : NCBIRPN1 [Mapview]
OMIM180470   
Gene and transcription
Genbank (Entrez)AK223595 AK296905 AK297513 AK297941 AK312369
RefSeq transcript (Entrez)NM_002950
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_005612 NW_001838883 NW_004929311
Consensus coding sequences : CCDS (NCBI)RPN1
Cluster EST : UnigeneHs.603636 [ NCBI ]
CGAP (NCI)Hs.603636
Alternative Splicing GalleryENSG00000163902
Gene ExpressionRPN1 [ NCBI-GEO ]     RPN1 [ SEEK ]   RPN1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04843 (Uniprot)
NextProtP04843  [Medical]
With graphics : InterProP04843
Splice isoforms : SwissVarP04843 (Swissvar)
Catalytic activity : Enzyme2.4.99.18 [ Enzyme-Expasy ]   2.4.99.182.4.99.18 [ IntEnz-EBI ]   2.4.99.18 [ BRENDA ]   2.4.99.18 [ KEGG ]   
Domains : Interpro (EBI)Ribophorin_I [organisation]  
Related proteins : CluSTrP04843
Domain families : Pfam (Sanger)Ribophorin_I (PF04597)   
Domain families : Pfam (NCBI)pfam04597   
DMDM Disease mutations6184
Blocks (Seattle)P04843
Human Protein AtlasENSG00000163902 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP04843
HPRD01598
IPIIPI00793589   IPI01015265   IPI00025874   IPI01011639   IPI00945851   
Protein Interaction databases
DIP (DOE-UCLA)P04843
IntAct (EBI)P04843
FunCoupENSG00000163902
BioGRIDRPN1
InParanoidP04843
Interologous Interaction database P04843
IntegromeDBRPN1
STRING (EMBL)RPN1
Ontologies - Pathways
Ontology : AmiGOdolichyl-diphosphooligosaccharide-protein glycotransferase activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  rough endoplasmic reticulum  translation  cellular protein modification process  SRP-dependent cotranslational protein targeting to membrane  oligosaccharyltransferase complex  gene expression  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  melanosome  post-translational protein modification  cellular protein metabolic process  poly(A) RNA binding  
Ontology : EGO-EBIdolichyl-diphosphooligosaccharide-protein glycotransferase activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum membrane  rough endoplasmic reticulum  translation  cellular protein modification process  SRP-dependent cotranslational protein targeting to membrane  oligosaccharyltransferase complex  gene expression  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  melanosome  post-translational protein modification  cellular protein metabolic process  poly(A) RNA binding  
Pathways : KEGGN-Glycan biosynthesis    Protein processing in endoplasmic reticulum   
Protein Interaction DatabaseRPN1
Wikipedia pathwaysRPN1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)RPN1
snp3D : Map Gene to Disease6184
SNP (GeneSNP Utah)RPN1
SNP : HGBaseRPN1
Genetic variants : HAPMAPRPN1
Exome VariantRPN1
1000_GenomesRPN1 
ICGC programENSG00000163902 
Cancer Gene: CensusRPN1 
Somatic Mutations in Cancer : COSMICRPN1 
CONAN: Copy Number AnalysisRPN1 
Mutations and Diseases : HGMDRPN1
Mutations and Diseases : intOGenRPN1
Genomic VariantsRPN1  RPN1 [DGVbeta]
dbVarRPN1
ClinVarRPN1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM180470   
MedgenRPN1
GENETestsRPN1
Disease Genetic AssociationRPN1
Huge Navigator RPN1 [HugePedia]  RPN1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneRPN1
Homology/Alignments : Family Browser (UCSC)RPN1
Phylogenetic Trees/Animal Genes : TreeFamRPN1
Chemical/Protein Interactions : CTD6184
Chemical/Pharm GKB GenePA34777
Clinical trialRPN1
Cancer Resource (Charite)ENSG00000163902
Other databases
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
CoreMineRPN1
iHOPRPN1
OncoSearchRPN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:15:54 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.