RPP21 (ribonuclease P/MRP subunit p21)

2018-11-01 Affiliation

Identity

HGNC

RPP21

LOCATION

6p22.1

LOCUSID

79897

ALIAS

C6orf135,CAT60

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79897
MIM: 612524
HGNC: 21300
Ensembl: ENSG00000241370

Variants:

dbSNP: 79897
ClinVar: 79897
TCGA: ENSG00000241370
COSMIC: RPP21

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000241370	ENST00000428040	Q9H633
ENSG00000241370	ENST00000433076	Q9H633
ENSG00000241370	ENST00000433076	A0A1U9X8H3
ENSG00000241370	ENST00000436442	Q9H633
ENSG00000241370	ENST00000442966	Q9H633

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
RNA transport	KEGG	ko03013
RNA transport	KEGG	hsa03013
Gene Expression	REACTOME	R-HSA-74160
tRNA processing	REACTOME	R-HSA-72306
tRNA processing in the nucleus	REACTOME	R-HSA-6784531
rRNA processing	REACTOME	R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol	REACTOME	R-HSA-6791226
rRNA processing in the nucleus and cytosol	REACTOME	R-HSA-8868773

References

Pubmed ID	Year	Title	Citations
19851445	2009	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	51
28432356	2017	A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks.	5

Citation

Dessen P

RPP21 (ribonuclease P/MRP subunit p21)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57690/rpp21